NASDAQ:GTHX - G1 Therapeutics, Inc.
$27.14
 $0.31
+1.16%
4:00PM EDT
2019-07-15
G1 Therapeutics, Inc., incorporated on May 19, 2008, is a clinical-stage biopharmaceutical company. The Company is engaged in developing small-molecule therapies for the treatment of cancer. Its two clinical-stage candidates are trilaciclib (G1T28) and G1T38, which are potent, selective inhibitors of the validated kinase targets CDK4/6. Trilaciclib and G1T38 are designed to be combined and enhance the anti-tumor activity of current therapies. It is also developing G1T48, an oral selective estrogen receptor degrader (SERD) for the treatment of breast cancer. The Company is evaluating trilaciclib in three Phase II clinical trials. G1T38 is being evaluated in combination with Faslodex in a Phase I b/II a trial for patients with estrogen receptor-positive, HER2-negative breast cancer.Trilaciclib Trilaciclib is a potential first-in-class, short-acting CDK4/6 inhibitor. In preclinical studies, administration of trilaciclib prior to chemotherapy has been shown to induce transient cell-cycle arrest of HSPCs, protect HSPCs from chemotherapy-induced damage, preserve bone marrow and immune system function, protect against bone marrow exhaustion, improve complete blood counts (CBC) recovery, prevent myeloid skewing and consequent lymphopenia, and enhance T-cell effector function in the tumor microenvironment. Read more at  reuters.com
sector:  health care
industry:  biotechnology
the data below are updated and published after 9pm EDT each trading day
  GTHX     avg for
industry  
  avg for
sector  
42 stocks weight:  41. 77   114. 77   204. 78  
42 stocks rank:  2. 50 K 1. 44 K 810. 33  
# analyst opinions:  6. 00   13. 59   13. 86  
mean recommendation:  1. 70   2. 12   2. 04  

quick ratio:  30. 11   5. 48   1. 89  
current ratio:  30. 21   5. 85   2. 40  

target price low:  25. 46   82. 72   115. 11  
target price avg:  55. 00   104. 42   138. 02  
target price high:  69. 00   130. 64   159. 47  
1-yr high:  67. 97   110. 27   142. 72  
last close:  26. 83   85. 12   126. 54  
50-day avg:  23. 65   86. 06   122. 35  
200-day avg:  26. 59   88. 76   121. 75  
1-yr low:  14. 40   69. 26   100. 63  
volume:  296. 47 K 3. 51 M 5. 53 M
50-day avg volume:  511. 13 K 3. 21 M 4. 22 M
200-day avg volume:  401. 16 K 3. 04 M 4. 75 M

1-day return:  1. 94 % -0. 30 % -1. 01 %
this week return:  -3. 80 % -2. 16 % -1. 35 %
12-wk return:  50. 65 % 3. 34 % 8. 69 %
52-wk return:  -37. 46 % -1. 76 % 12. 22 %

enterprise value (EV):  801. 74 M 46. 50 B 123. 99 B
market cap:  988. 56 M 40. 77 B 109. 11 B
EBITDA:  -94. 23 M 4. 33 B 8. 19 B
enterprise multiple (EV/EBITDA):  -8. 51   5. 45   12. 05  
total debt:  1. 55 M 11. 27 B 17. 58 B
debt/equity:  0. 46   57. 36   120. 25  
net income (common):  -88. 83 M 2. 13 B 4. 27 B

shares outstanding:  37. 47 M 551. 08 M 1. 24 B
shares:  27. 80 M 559. 41 M 1. 22 B
shares short:  3. 67 M 11. 15 M 11. 94 M
shares short prior month:  3. 51 M 9. 31 M 11. 96 M
short ratio:  9. 88   5. 72   3. 43  
short % of float:  15. 19 % 6. 40 % 2. 65 %
total cash/share:  9. 28   11. 00   9. 23  
total cash:  347. 80 M 6. 03 B 6. 01 B
free cash flow:  -48. 85 M 3. 02 B 4. 96 B
operating cash flow:  -77. 74 M 3. 92 B 5. 99 B

book value:  9. 05   13. 02   27. 49  
price/book:  2. 97   4. 21   8. 80  
gross profits:  -70. 68 M 7. 67 B 36. 29 B
operating margins:  0. 00 % -380. 20 % -38. 44 %
EBITDA margins:  0. 00 % 13. 59 % 23. 24 %
profit margins:  0. 00 % 10. 94 % 14. 00 %
gross margins:  0. 00 % 36. 11 % 55. 16 %

1-yr max volatility:  42. 42 % --- ---
1-yr mean volatility:  3. 28 % 1. 50 % 1. 08 %

1-yr EPS:  -2. 52   2. 12   4. 26  
forward EPS:  -3. 75   3. 47   7. 14  
P/E:  -10. 67   2. 15   33. 17  
forward P/E:  -7. 22   -4. 03   17. 60  
PE/G:  1. 62   0. 54   0. 34  
growth:  -6. 60 % 263. 03 % 78. 34 %
earnings high:  -0. 67   0. 91   1. 70  
earnings avg:  -0. 72   0. 71   1. 58  
earnings low:  -0. 85   0. 48   1. 46  
revenue high:  -0. 00   2. 64 B 11. 26 B
revenue avg:  -0. 00   2. 58 B 11. 09 B
revenue low:  -0. 00   2. 54 B 10. 90 B
return on assets:  -21. 57 % -2. 31 % 5. 31 %
return on equity:  -34. 03 % -82. 48 % 135. 30 %

beta (1yr vs S&P500):  2. 09   1. 26   0. 91  
sharpe (1yr):  -0. 12   0. 07   0. 77  

held % insiders:  17. 81 % 6. 08 % 3. 31 %
held % institutions:  89. 86 % 78. 36 % 69. 61 %

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the data below are updated and re-published at 8pm EDT after each trading day

2019-07-14 : GTHX
.    136.777 =       136.777 :: --> INITIAL WEIGHT <--
.    - 2.515 =       134.262 :: earnings per-share addition
.                               --> FUNDAMENTALS <--
.    x 2.221 =       298.204 :: P/E factor
.    x 0.959 =       285.963 :: PE/G factor
.     x 1.43 =       408.834 :: beta factor
.     x 0.68 =       277.915 :: sharpe factor
.    x 4.838 =      1344.684 :: current ratio factor
.    x 1.017 =      1367.582 :: quick ratio factor
.    x 1.049 =      1435.124 :: short ratio factor
.     x 1.03 =      1478.379 :: price-to-book factor
.    x 1.004 =      1484.244 :: debt-to-equity factor
.                               --> PERFORMANCE <--
.    x 2.114 =      3137.669 :: sector+industry 1-year gains factor
.    x 1.033 =      3242.461 :: industry 12-weeks return factor
.    x 1.305 =      4232.298 :: industry 2-weeks return factor
.    x 0.908 =      3843.022 :: company one-year gains+dividend factor
.    x 2.996 =     11514.678 :: company 13 weeks' performance factor
.    x 1.024 =     11789.197 :: 5-day avg > 200-day avg
.    x 1.578 =     18605.895 :: 5-day avg > 50-day avg
.    x 0.971 =     18060.396 :: "drift" penalty 1 days ago
.    / 2.099 =      8605.159 :: overall "drift" factor
.    x 0.569 =      4899.021 :: largest single-day jump factor
.    x 0.988 =      4840.683 :: volatility factor
.    x 0.987 =      4778.994 :: 42-day volatility factor
.     x 1.41 =      6738.087 :: notable returns + performance factor
.    x 2.511 =     16916.495 :: performance vs s&p500 factor
.    x 2.263 =      38288.31 :: inverse volume-to-price factor
.                               --> PROJECTIONS <--
.    x 0.657 =     25138.906 :: forward EPS factor
.    x 0.875 =     22001.667 :: forward P/E factor
.    x 1.182 =     26015.846 :: industry recommendation factor
.    x 2.565 =     66733.202 :: company recommendation factor
.    x 1.008 =       67243.6 :: factor historical industry gain for week 28
.    x 0.966 =     64928.601 :: target low factor
.    x 1.342 =      87105.35 :: target mean factor
.    x 1.053 =     91691.894 :: target high factor
.   x 10.977 =   1006467.053 :: spline projection factor
.                               --> FINAL ADJUSTMENTS <--
.  quad root =        31.674 :: reduced for readability
.    + 9.637 =         41.31 :: add/subtract for investor sentiment
.     + 0.46 =         41.77 :: earnings report in 22 days
.                               --> FINAL WEIGHT <--
.                      41.77 :: FINAL WEIGHT for NASDAQ:GTHX


 


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