NASDAQ:IONS - Ionis Pharmaceuticals, Inc.
$67.86
 $2.34
+3.57%
4:00PM EDT
2019-07-15
Ionis Pharmaceuticals, Inc. is engaged in discovering and developing ribonucleic acid (RNA)-targeted therapeutics. The Company, using its drug discovery platform, has developed a pipeline of drugs for patients with unmet medical needs. The Company's segments include Ionis Core and Akcea Therapeutics. In the Ionis Core segment, the Company is engaged in exploiting a drug discovery platform to generate a pipeline of drugs for the Company and its partners. The Akcea Therapeutics segment includes the operations of the Company's subsidiary, Akcea Therapeutics, Inc. (Akcea Therapeutics). Akcea Therapeutics is focused on developing and commercializing volanesorsen and other clinical-stage drugs for serious cardiometabolic diseases caused by lipid disorders. The Company is developing volanesorsen to treat two severe and rare, genetically defined diseases, familial chylomicronemia (FCS) and familial partial lipodystrophy (FPL). The Company offers SPINRAZA, a Generation 2.0+ antisense drug. Read more at  reuters.com
sector:  health care
industry:  biotechnology
the data below are updated and published after 9pm EDT each trading day
  IONS     avg for
industry  
  avg for
sector  
42 stocks weight:  107. 31   114. 77   204. 78  
42 stocks rank:  1. 38 K 1. 44 K 810. 33  
# analyst opinions:  14. 00   13. 59   13. 86  
mean recommendation:  2. 90   2. 12   2. 04  

quick ratio:  8. 98   5. 48   1. 89  
current ratio:  9. 40   5. 85   2. 40  

target price low:  19. 00   82. 72   115. 11  
target price avg:  69. 57   104. 42   138. 02  
target price high:  106. 00   130. 64   159. 47  
1-yr high:  86. 14   110. 27   142. 72  
last close:  65. 52   85. 12   126. 54  
50-day avg:  65. 93   86. 06   122. 35  
200-day avg:  61. 97   88. 76   121. 75  
1-yr low:  43. 09   69. 26   100. 63  
volume:  711. 71 K 3. 51 M 5. 53 M
50-day avg volume:  1. 39 M 3. 21 M 4. 22 M
200-day avg volume:  1. 15 M 3. 04 M 4. 75 M

1-day return:  0. 11 % -0. 30 % -1. 01 %
this week return:  1. 47 % -2. 16 % -1. 35 %
12-wk return:  -10. 23 % 3. 34 % 8. 69 %
52-wk return:  43. 01 % -1. 76 % 12. 22 %

enterprise value (EV):  7. 74 B 46. 50 B 123. 99 B
market cap:  9. 14 B 40. 77 B 109. 11 B
EBITDA:  77. 53 M 4. 33 B 8. 19 B
enterprise multiple (EV/EBITDA):  99. 85   5. 45   12. 05  
enterprise/revenue (EV/R):  10. 29   50. 46   9. 50  
total revenue:  752. 47 M 10. 21 B 40. 60 B
total debt:  668. 08 M 11. 27 B 17. 58 B
debt/equity:  48. 15   57. 36   120. 25  
net income (common):  365. 62 M 2. 13 B 4. 27 B

shares outstanding:  140. 32 M 551. 08 M 1. 24 B
shares:  127. 64 M 559. 41 M 1. 22 B
shares short:  15. 47 M 11. 15 M 11. 94 M
shares short prior month:  15. 29 M 9. 31 M 11. 96 M
short ratio:  11. 18   5. 72   3. 43  
short % of float:  13. 26 % 6. 40 % 2. 65 %
total cash/share:  16. 08   11. 00   9. 23  
total cash:  2. 26 B 6. 03 B 6. 01 B
free cash flow:  205. 75 M 3. 02 B 4. 96 B
operating cash flow:  697. 43 M 3. 92 B 5. 99 B

book value:  8. 65   13. 02   27. 49  
price/book:  7. 58   4. 21   8. 80  
gross profits:  184. 05 M 7. 67 B 36. 29 B
operating margins:  8. 54 % -380. 20 % -38. 44 %
EBITDA margins:  10. 30 % 13. 59 % 23. 24 %
profit margins:  47. 79 % 10. 94 % 14. 00 %
gross margins:  44. 31 % 36. 11 % 55. 16 %

1-yr max volatility:  16. 06 % --- ---
1-yr mean volatility:  1. 98 % 1. 50 % 1. 08 %

1-yr EPS:  2. 65   2. 12   4. 26  
forward EPS:  0. 26   3. 47   7. 14  
P/E:  24. 69   2. 15   33. 17  
forward P/E:  251. 73   -4. 03   17. 60  
PE/G:  0. 23   0. 54   0. 34  
growth:  105. 80 % 263. 03 % 78. 34 %
earnings high:  -0. 05   0. 91   1. 70  
earnings avg:  -0. 27   0. 71   1. 58  
earnings low:  -0. 50   0. 48   1. 46  
revenue high:  193. 10 M 2. 64 B 11. 26 B
revenue avg:  146. 03 M 2. 58 B 11. 09 B
revenue low:  126. 00 M 2. 54 B 10. 90 B
return on assets:  1. 94 % -2. 31 % 5. 31 %
return on equity:  35. 69 % -82. 48 % 135. 30 %
revenue growth:  105. 80 % 262. 60 % 72. 94 %
revenue/share:  5. 55   12. 77   61. 38  

beta (1yr vs S&P500):  1. 29   1. 26   0. 91  
sharpe (1yr):  1. 05   0. 07   0. 77  

held % insiders:  9. 13 % 6. 08 % 3. 31 %
held % institutions:  85. 90 % 78. 36 % 69. 61 %

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the data below are updated and re-published at 8pm EDT after each trading day

2019-07-14 : IONS
.    145.585 =       145.585 :: --> INITIAL WEIGHT <--
.    + 2.654 =       148.239 :: earnings per-share addition
.                               --> FUNDAMENTALS <--
.    x 2.885 =       427.732 :: P/E factor
.    x 1.439 =       615.425 :: PE/G factor
.     x 1.57 =       965.965 :: beta factor
.    x 1.048 =      1011.856 :: sharpe factor
.    x 2.394 =      2422.065 :: current ratio factor
.    x 1.061 =      2569.399 :: quick ratio factor
.    x 1.044 =      2681.849 :: short ratio factor
.    x 1.019 =       2733.93 :: return on assets factor
.    x 1.531 =      4185.112 :: return on equity factor
.    x 2.115 =      8852.424 :: revenue growth factor
.    x 1.204 =     10657.107 :: EV/R factor
.    x 1.088 =     11593.576 :: price-to-book factor
.    x 2.251 =     26102.718 :: EBITDA vs industry factor
.    x 1.126 =     29399.901 :: debt-to-revenue factor
.    x 1.356 =     39874.785 :: debt-to-equity factor
.                               --> PERFORMANCE <--
.    x 2.114 =     84294.675 :: sector+industry 1-year gains factor
.    x 1.033 =     87109.951 :: industry 12-weeks return factor
.    x 1.305 =    113702.326 :: industry 2-weeks return factor
.    x 1.437 =    163408.124 :: company one-year gains+dividend factor
.    x 3.414 =    557881.288 :: company 13 weeks' performance factor
.    x 1.103 =     615212.63 :: 5-day avg > 200-day avg
.    x 1.064 =    654511.896 :: 50-day avg > 200-day avg
.    x 0.996 =    651591.098 :: "drift" penalty 2 days ago
.    / 1.801 =    361882.603 :: overall "drift" factor
.    x 0.923 =    334194.209 :: largest single-day jump factor
.    x 0.993 =    331790.007 :: volatility factor
.    x 0.995 =    330215.765 :: 42-day volatility factor
.    x 2.434 =    803678.867 :: notable returns + performance factor
.    x 3.278 =   2634555.175 :: inverse volume-to-price factor
.                               --> PROJECTIONS <--
.    x 0.764 =   2013987.506 :: forward EPS factor
.    x 0.914 =   1841602.332 :: forward P/E factor
.    x 1.182 =   2177600.571 :: industry recommendation factor
.    x 1.638 =   3567795.052 :: company recommendation factor
.    x 1.008 =   3595082.767 :: factor historical industry gain for week 28
.    x 0.871 =   3132752.437 :: target low factor
.    x 1.083 =   3392376.767 :: target mean factor
.    x 1.033 =   3504368.684 :: target high factor
.    x 9.805 =  34361172.764 :: spline projection factor
.                               --> FINAL ADJUSTMENTS <--
.  quad root =        76.563 :: reduced for readability
.   + 29.089 =       105.652 :: add/subtract for investor sentiment
.     + 1.66 =       107.311 :: earnings report in 19 days
.                               --> FINAL WEIGHT <--
.                    107.311 :: FINAL WEIGHT for NASDAQ:IONS


 


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