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Health Care

SECTOR	industry1	INDUSTRY	EXCH	SYM	NAME	42s WEIGHT	42s RANK	PRICE	# OPINION	REC MEAN	1d %	1w %	12w %	52w %	52w LOW	52w HI	50d AVG	200d AVG	EX-DIV	DIV RATE	DIV YLD	$ TGT LOW	$ TGT AVG	$ TGT HI	MKT CAP	VOLUME	50d VOL	200d VOL	EPS	FW EPS	P/E	FW P/E	PE/G	BETA	SHARPE	QK RATIO	CUR RATIO	E/V	EBITDA	EV/EBITDA	EV/R	REVENUE	DEBT	DEBT/EQTY	INCOME	SHRS OSTDG	FLT SHRS	SHRS SHRT	SHRS SHRT PR MO	SHRT RATIO	SHORT %	CSH/SHR	SUM CASH	FREE CASH	OPTG CASH	BOOK	PR/BK	PROFIT	OP MRGN	EBITDA MRGN	PFT MRGN	GRS MRGN	MAX VLTY	AVG VLTY	EARN GRW	ROA	ROE	REV GRW	REV/SHARE	REV/QTR GRW	% INSDR	% INST
HEALTH CARE	--	--	--	--	2021-04-16 . sector average -->	413.91	1,339	186.20	15	2.0	0.76	2.66	1.83	5.07	124.93	203.36	176.86	166.59	3690-04-17	1.89	1.56	162.74	202.29	231.40	6,634,914,000,984	1,014,024,289	1,613,990,580	1,353,905,594	5.25	8.69	55.76	17.37	4.17	0.00	2.02	2.23	2.66	7,474,149,170,153	488,468,714,132	48.67	198.77	3,285,570,272,089	1,290,839,059,688	128.97	191,858,940,563	107,953,043,485	85,598,141,941	3,818,626,227	3,527,696,806	3.12	0.02	13.33	578,594,824,361	295,295,703,320	417,268,377,071	7,367.95	7.49	1,148,914,847,288	-827.37	17.09	4.61	51.63	12.07	1.56	-5.20	4.42	19.50	122.85	75.89	0.00	2.64	70.07
HEALTH CARE	Biotechnology	Biotechnology	--	--	2021-04-16 . industry average -->	344.33	1,590	143.58	17	2.1	0.69	2.75	-4.20	11.01	102.69	179.69	141.11	137.24		1.82	1.36	122.00	168.63	212.91	1,228,775,888,118	412,877,890	720,630,614	622,988,270	2.93	8.02	84.69	7.66	-1.76	0.00	1.95	5.00	5.38	1,267,146,018,265	37,371,605,929	8.06	331.25	166,517,072,984	193,166,491,807	181.49	-6,638,001,657	34,855,622,224	24,786,305,478	2,071,304,670	1,875,185,819	4.52	0.05	13.08	147,480,455,658	33,177,467,544	35,585,233,744	1,752.24	-0.61	106,336,402,278	-2,167.11	-7.73	-23.59	33.87	21.50	2.23	-19.10	-2.67	-78.90	517.74	20.73	0.00	4.43	70.77
HEALTH CARE	Biotechnology	Biotechnology	NYSE	ABBV	AbbVie Inc.	245.10	2,105	107.91	23	2.0	0.95	0.34	-3.01	33.92	79.11	113.41	106.55	99.38	2021-04-14	5.20	4.84	97.00	122.17	144.00	187,036,200,000	8,192,624	7,158,535	7,483,270	2.71	13.80	39.82	7.79	-0.40	0.56	1.15	0.60	0.84	268,534,923,264	22,169,999,360	12.11	5.86	45,803,999,232	87,096,999,936	665.02	4,556,000,256	1,764,825,805	1,737,804,171	16,201,312	14,278,312	2.44	0.01	4.81	8,486,000,128	16,861,124,608	17,588,000,768	7.41	14.57	31,747,000,000	34.27	48.40	10.08	69.31	7.32	1.17	-99.50	8.19	187.70	59.20	27.48	0.00	0.10	69.80
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ABEO	Abeona Therapeutics Inc.	189.95	2,599	1.49	3	1.7	-0.67	-9.15	-24.75	-38.40	0.99	3.79	2.19	2.01		0.00	0.00	1.80	2.55	4.00	177,820,100	1,577,376	4,120,268	2,501,305	-0.91	-0.73	-1.64	-2.19	0.08	0.51	0.04	2.27	2.33	65,831,956	-43,918,000	-1.50	6.58	10,000,000	8,731,000	8.51	-84,234,000	99,038,933	76,512,029	4,878,409	3,411,780	2.13	0.06	0.96	95,034,000	-14,909,375	-35,019,000	1.07	1.40	-20,139,000	-485.04	0.00	0.00	-201.39	41.26	4.25	0.00	-16.19	-59.96	0.00	0.11	0.00	14.91	34.35
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ABIO	ARCA biopharma Inc.	0.00	4,019	3.36	0	0.0	-1.18	-7.44	-27.74	7.08	3.20	22.00	4.19	4.74		0.00	0.00	0.00	0.00	0.00	53,029,330	432,636	1,067,969	823,641	-2.07	-8.80	-1.63	-0.41	-0.00	0.23	0.58	14.02	14.28	3,687,819	-9,758,000	-0.38	0.00	0	450,000	0.97	-9,738,000	14,410,143	14,372,965	324,708	119,719	0.24	0.02	3.41	49,071,000	-4,240,375	-7,725,000	4.87	0.69	0	0.00	0.00	0.00	0.00	386.44	4.65	0.00	-20.70	-35.98	0.00	0.00	0.00	0.26	5.70
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ABUS	Arbutus Biopharma Corporation	200.62	2,505	3.07	7	2.1	-4.06	-6.97	-22.48	190.65	1.02	9.02	3.71	3.45		0.00	0.00	3.18	3.75	6.11	320,733,300	1,989,236	2,290,876	4,757,961	-1.00	-0.67	-3.07	-4.73	0.09	0.62	1.18	13.06	13.39	344,549,920	-55,291,000	-6.23	49.83	6,914,000	2,983,000	2.93	-75,868,000	96,336,352	69,807,801	4,135,566	3,270,674	2.30	0.05	1.29	123,268,000	-30,169,000	-51,441,000	-0.53	-5.80	-40,567,000	-828.31	0.00	0.00	0.00	119.23	4.87	0.00	-29.51	-72.97	47.50	0.09	0.00	18.71	25.42
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ACAD	ACADIA Pharmaceuticals Inc.	177.53	2,720	21.15	18	2.5	-0.24	3.73	-59.34	0.00	20.12	58.72	35.50	44.30		0.00	0.00	18.00	22.28	29.44	4,138,828,000	4,776,170	2,754,434	1,597,734	-1.79	-1.23	-11.82	-16.58	0.38	0.56	-0.82	6.44	6.77	2,680,956,928	-230,854,000	-11.61	6.07	441,755,008	49,547,000	7.90	-281,584,000	160,047,470	117,750,125	6,515,115	6,132,529	2.00	0.07	3.95	631,958,016	-59,698,248	-136,166,000	3.93	5.38	154,875,000	-52.92	-52.26	-63.74	35.06	45.12	2.42	0.00	-18.66	-42.47	23.10	2.81	0.00	0.40	94.40
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ACHV	Achieve Life Sciences Inc.	188.02	2,621	9.93	5	1.7	-2.93	-12.90	-20.88	48.89	6.60	18.26	12.24	9.87		0.00	0.00	10.00	14.39	21.00	72,815,020	134,922	128,018	345,212	-5.42	-3.49	-1.83	-3.01	0.05	1.06	0.83	12.22	12.60	30,241,110	-14,495,000	-2.09	0.00	0	167,000	0.45	-14,730,000	6,149,917	6,088,725	458,921	427,562	3.91	0.07	5.83	35,853,000	-7,969,750	-13,474,000	6.10	1.63	0	0.00	0.00	0.00	0.00	25.42	4.01	0.00	-30.04	-53.24	0.00	0.00	0.00	0.45	18.84
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ACIU	AC Immune SA	422.76	978	6.73	4	1.7	-4.67	-2.04	11.61	0.00	4.42	13.00	7.59	6.49		0.00	0.00	8.80	13.89	17.09	554,714,100	131,042	1,091,420	781,714	-0.93	-0.07	-7.22	-98.14	0.08	1.05	0.26	16.25	16.53	241,440,784	-59,725,000	-4.04	15.65	15,431,000	2,223,000	1.03	-61,921,000	72,701,715	21,508,158	1,511,534	1,162,918	2.23	0.05	3.34	225,892,992	-38,581,500	-59,517,000	3.22	2.09	-44,056,000	-396.99	-46.53	-51.20	-285.50	44.90	3.12	0.00	-14.23	-25.38	9.80	0.22	0.00	51.34	28.87
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ACOR	Acorda Therapeutics Inc.	69.42	3,698	4.19	2	3.0	6.62	0.00	-41.97	0.00	2.52	9.84	5.75	4.79		0.00	0.00	3.00	5.00	5.57	46,974,870	173,495	251,920	804,156	-12.32	-4.59	-0.34	-0.91	0.01	0.87	0.16	0.67	1.61	228,319,344	-45,656,000	-5.00	1.49	152,967,008	259,948,992	109.24	-99,594,000	9,489,873	7,719,012	1,068,815	750,157	3.58	0.13	7.53	71,369,000	-103,826,000	-61,006,000	25.13	0.17	96,785,000	-56.58	-29.85	-65.11	63.27	44.48	4.39	0.00	-7.55	-36.30	-24.40	18.92	0.00	2.02	25.74
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADAP	Adaptimmune Therapeutics plc	210.71	2,425	4.93	6	2.4	-2.18	-2.38	-9.04	0.00	3.20	13.40	5.57	6.57		0.00	0.00	5.41	6.00	11.33	795,857,700	756,820	881,308	1,151,399	-0.91	-1.07	-5.40	-4.72	-0.31	1.49	0.76	9.95	10.19	438,940,608	-125,811,000	-3.49	110.90	3,958,000	23,711,000	6.95	-130,092,000	930,827,670	126,338,137	1,837,439	1,512,930	2.02	0.00	2.37	368,216,992	-62,812,124	-53,591,000	2.20	2.24	-87,610,000	-3,370.52	0.00	0.00	0.00	127.61	4.45	0.00	-26.36	-55.97	106.30	0.03	0.00	0.22	76.50
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADMA	ADMA Biologics Inc	139.63	3,101	1.65	6	1.8	-4.62	-6.25	-31.82	0.00	1.57	4.20	2.19	2.35		0.00	0.00	1.10	1.91	2.76	189,874,200	2,261,593	3,221,712	4,206,049	-0.88	-0.19	-1.88	-9.26	0.02	0.34	-0.24	3.47	7.71	255,192,176	-53,472,584	-4.77	6.04	42,219,784	97,668,696	110.67	-75,748,544	123,044,981	103,019,778	8,537,955	8,750,951	2.89	0.10	0.46	55,921,152	-80,490,048	-102,002,960	0.84	1.96	-11,571,643	-135.99	-126.65	-179.41	-27.41	31.84	3.48	0.00	-21.44	-132.38	15.90	0.49	0.00	1.92	41.79
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADMS	Adamas Pharmaceuticals Inc.	118.58	3,304	5.09	8	2.2	-0.20	12.61	12.86	48.26	2.43	9.15	5.25	4.47		0.00	0.00	3.00	10.44	6.37	211,798,800	1,135,360	610,708	470,916	-2.03	-0.88	-2.51	-5.78	0.04	0.97	0.85	2.66	3.21	210,805,952	-38,313,000	-5.50	2.83	74,461,000	138,272,000	0.00	-57,403,000	43,068,421	22,365,385	2,353,418	1,986,552	4.93	0.06	2.73	83,365,000	-30,478,376	-50,708,000	-1.73	-2.94	72,423,000	-52.60	-51.45	-77.09	97.26	44.64	3.58	0.00	-17.35	0.00	28.50	2.63	0.00	2.99	59.54
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADVM	Adverum Biotechnologies Inc.	158.38	2,928	8.86	9	2.1	-5.75	-2.42	-33.98	0.00	8.75	26.98	11.29	12.94		0.00	0.00	9.55	12.00	24.89	972,093,500	1,072,021	782,067	1,027,979	-1.38	-2.00	-6.42	-4.54	-0.14	1.67	-0.03	20.59	20.82	489,067,840	-113,792,000	-4.30	2,883.33	250,000	30,808,000	7.09	-117,507,000	97,796,128	61,921,574	10,221,928	9,463,621	13.44	0.11	4.39	429,728,992	-54,863,752	-79,291,000	4.45	1.99	-73,309,000	-36,120.80	0.00	0.00	0.00	38.51	3.74	0.00	-20.90	-38.57	0.00	0.00	0.00	0.74	98.88
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADXS	Advaxis Inc.	19.73	3,994	0.47	0	2.0	-9.62	-29.85	-40.51	-18.27	0.26	1.57	0.85	0.57		0.00	0.00	0.00	0.00	0.00	93,183,960	9,031,673	9,683,011	6,543,129	-0.33	-0.55	-1.44	-0.85	-0.02	1.34	0.29	9.32	9.93	34,496,068	-18,800,000	-1.84	18.50	1,865,000	5,787,000	15.40	-22,589,000	137,960,068	113,372,628	5,278,811	4,694,368	0.92	0.04	0.28	33,318,000	-9,525,125	-17,018,000	0.32	1.45	253,000	-1,070.94	0.00	0.00	100.00	32.36	4.65	0.00	-25.66	-57.10	53,733.30	0.03	0.00	0.06	12.80
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AEZS	Aeterna Zentaris Inc.	46.44	3,853	0.88	0	0.0	-3.30	-20.00	14.29	4.44	0.29	3.62	1.28	0.66		0.00	0.00	0.00	0.00	0.00	142,363,800	3,240,098	17,851,607	9,067,144	-0.13	1.78	-7.04	0.54	0.00	1.44	0.73	5.18	5.56	109,150,264	-5,896,000	-18.51	29.89	3,652,000	184,000	1.39	-5,118,000	121,153,785	121,072,701	7,725,613	3,641,480	0.55	0.06	0.20	24,271,000	-3,361,000	-4,129,000	0.21	4.17	1,335,000	-162.24	-161.45	-140.14	36.56	200.88	5.72	0.00	-12.94	-95.24	13,044.40	0.09	0.00	0.05	3.27
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AFMD	Affimed N.V.	648.65	361	9.51	6	1.7	0.32	-2.36	44.53	360.00	1.88	10.79	7.11	5.19		0.00	0.00	9.99	14.16	16.00	815,793,300	2,307,022	3,802,092	1,935,982	-0.61	-0.41	-15.69	-25.20	0.49	1.28	2.15	2.21	2.24	778,589,504	-34,816,000	-22.36	34.51	22,560,000	2,388,000	5.08	-39,486,000	117,286,342	82,395,830	7,580,304	7,470,027	3.60	0.07	1.10	97,343,000	-2,769,625	-33,573,000	0.53	17.88	21,410,000	-157.41	-154.33	-175.03	100.00	22.52	3.72	0.00	-22.94	-114.04	401.40	0.29	0.00	2.67	59.52
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AGEN	Agenus Inc.	273.60	1,866	2.62	2	1.3	-1.50	-6.09	-23.39	-0.74	2.28	5.95	3.54	3.75		0.00	0.00	2.55	7.00	7.50	583,353,500	2,868,395	4,118,068	2,848,342	-1.05	-1.25	-2.50	-2.17	-0.13	1.07	0.33	0.78	0.88	545,808,384	-108,835,000	-5.02	6.19	88,170,000	56,539,000	0.00	-181,123,008	204,685,422	161,566,391	27,024,481	24,228,469	6.07	0.15	0.49	99,871,000	-79,449,504	-139,096,000	-1.04	-2.52	-56,796,000	-131.58	-123.44	-205.19	-64.42	29.52	3.36	0.00	-39.21	0.00	-9.40	0.51	0.00	8.12	52.45
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AGIO	Agios Pharmaceuticals Inc.	215.62	2,385	54.69	9	2.0	-0.64	3.64	14.53	0.00	32.47	58.93	51.55	44.72		0.00	0.00	50.00	64.89	80.00	3,455,010,000	1,120,668	789,890	744,603	-4.75	-6.10	-11.53	-8.65	-0.40	0.92	0.60	6.34	6.75	3,466,401,280	-306,164,992	-11.32	17.06	203,196,000	366,468,000	91.73	-327,369,984	69,811,806	68,873,998	6,260,121	5,679,507	8.40	0.12	8.23	572,929,024	-154,449,120	-290,759,008	5.77	9.49	-167,079,000	-155.59	-150.68	-161.11	-82.23	28.25	2.58	0.00	-22.66	-62.95	24.30	2.95	0.00	1.04	94.41
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AGLE	Aeglea BioTherapeutics Inc.	203.81	2,481	8.17	7	2.1	2.77	5.97	9.81	0.00	5.10	11.38	7.69	7.79		0.00	0.00	8.28	9.00	15.86	366,841,400	182,213	195,257	241,404	-1.52	-1.10	-5.39	-7.01	0.20	1.44	0.86	8.90	9.11	229,449,520	-80,485,000	-2.85	0.00	0	5,520,000	3.95	-80,893,000	48,015,892	28,786,007	2,018,895	1,792,688	10.34	0.04	3.05	146,272,992	-50,796,624	-75,775,000	2.92	2.80	-59,638,000	-535.07	0.00	0.00	0.00	27.93	3.28	0.00	-41.61	-80.93	0.00	0.00	0.00	2.57	93.73
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AGTC	Applied Genetic Technologies Corporation	148.78	3,021	3.99	8	1.7	-1.24	-9.52	-14.74	3.32	3.56	9.67	5.34	5.14		0.00	0.00	3.50	5.09	8.00	217,128,600	2,508,484	3,675,393	1,248,225	-2.27	-1.73	-1.76	-2.34	0.07	0.80	0.40	3.73	3.87	134,364,400	-54,742,000	-2.46	0.00	2,453,000	14,697,000	35.40	-56,534,000	42,657,878	36,267,728	3,253,168	2,355,684	1.79	0.08	1.25	53,097,000	-33,649,752	-48,892,000	1.60	2.49	-13,933,000	-2,038.89	-83.02	-79.52	48.84	30.59	3.82	0.00	-45.55	-111.33	0.00	0.00	0.00	0.66	52.25
HEALTH CARE	Biotechnology	Biotechnology	AMEX	AIM	AIM ImmunoTech Inc.	113.48	3,350	2.10	3	2.0	-0.47	-6.67	-1.41	-15.60	1.60	4.30	2.35	2.25		0.00	0.00	5.00	2.04	2.47	88,289,670	521,811	2,916,375	3,364,255	-5.87	-1.00	-0.36	-2.10	0.00	0.76	0.25	36.41	36.58	64,919,284	-14,126,000	-4.60	398.28	163,000	2,285,000	3.73	-14,400,000	47,821,935	47,370,018	1,573,347	1,698,349	1.45	0.03	0.82	39,002,000	-8,110,875	-10,368,000	2.14	0.98	-643,000	-9,115.95	0.00	0.00	0.00	32.28	3.99	0.00	-21.77	-38.54	-16.00	0.01	0.00	0.97	6.44
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AKBA	Akebia Therapeutics Inc.	148.11	3,026	2.96	7	2.2	-3.27	-3.27	-6.03	0.00	2.09	13.71	3.65	5.01		0.00	0.00	3.00	3.18	6.71	485,067,700	3,995,657	5,898,723	5,866,878	-2.77	-0.69	-1.07	-4.43	0.01	2.45	-0.00	1.59	1.99	327,312,448	-139,012,992	-2.36	1.11	295,307,008	126,285,000	38.92	-383,456,992	153,502,435	151,764,787	25,126,126	26,352,568	3.92	0.19	1.75	268,689,984	-17,894,624	-110,388,000	1.67	1.77	12,859,000	-58.45	-47.07	-129.85	4.35	73.26	3.97	0.00	-15.24	-119.39	-18.50	2.13	0.00	1.36	68.45
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AKRO	Akero Therapeutics Inc.	257.33	2,001	27.34	7	1.6	-0.94	-1.51	-8.53	21.34	18.36	41.16	30.49	30.85		0.00	0.00	25.78	46.00	60.71	1,018,423,000	155,253	245,629	276,397	-2.52	-4.48	-10.86	-5.90	-0.14	0.83	0.75	20.47	20.70	698,535,040	-80,137,000	-8.72	0.00	0	1,698,000	0.66	-79,207,000	34,770,319	17,114,994	2,870,517	2,225,478	9.28	0.15	7.72	268,387,008	-41,954,248	-70,804,000	7.45	3.67	0	0.00	0.00	0.00	0.00	33.78	2.72	0.00	-24.35	-40.89	0.00	0.00	0.00	7.26	96.59
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALBO	Albireo Pharma Inc.	676.44	316	32.60	7	1.5	-0.97	-0.85	-6.54	0.00	17.00	49.00	36.02	34.06		0.00	0.00	65.00	73.00	82.00	667,447,000	100,027	163,191	255,678	-6.73	-4.51	-4.84	-7.29	0.15	0.70	1.14	9.94	10.36	391,007,264	-96,079,000	-4.07	47.06	8,308,000	13,824,000	7.63	-107,633,000	19,113,603	16,643,934	1,670,481	1,447,299	9.64	0.10	13.15	251,272,000	-47,212,624	-101,029,000	9.49	3.44	8,308,000	-1,158.78	0.00	0.00	100.00	44.45	2.84	0.00	-26.70	-78.45	-57.80	0.52	0.00	0.95	94.83
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALDX	Aldeyra Therapeutics Inc.	441.48	908	11.28	12	1.5	-2.51	-6.31	-4.33	272.46	2.50	14.62	11.96	8.49		0.00	0.00	15.00	25.00	32.00	527,274,800	489,411	842,071	896,433	-1.11	-1.15	-10.20	-10.22	-2.56	0.87	1.93	4.26	6.69	499,193,408	-34,610,536	-14.42	0.00	0	15,327,542	25.76	-37,553,728	47,246,847	37,939,218	4,781,945	1,801,286	5.88	0.11	1.12	52,858,312	-20,278,344	-37,493,456	1.54	7.33	0	0.00	0.00	0.00	0.00	25.28	4.23	0.00	-27.28	-69.81	0.00	0.00	0.00	1.87	56.31
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALEC	Alector Inc.	356.30	1,326	17.80	8	1.6	-3.68	2.48	9.81	-21.88	9.12	34.89	18.62	15.64		0.00	0.00	28.00	31.88	41.00	1,301,206,000	754,786	699,610	782,301	-2.45	-2.61	-7.28	-7.08	-1.09	1.06	-0.00	6.07	6.19	1,036,246,656	-189,066,000	-5.48	49.12	21,098,000	51,256,000	19.16	-190,228,000	79,584,442	56,593,293	5,808,385	5,408,887	7.12	0.13	5.19	413,308,000	-87,748,000	-166,734,000	3.37	5.28	-135,771,000	-923.96	0.00	0.00	100.00	23.47	3.55	0.00	-26.77	-82.30	-19.10	0.27	0.00	12.76	75.71
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALKS	Alkermes plc	228.06	2,267	19.87	9	3.0	0.51	4.47	-7.45	0.00	13.03	23.92	19.74	18.96		0.00	0.00	15.00	21.89	28.00	3,108,323,000	1,318,699	1,220,418	1,279,405	-0.70	0.94	-28.47	20.23	0.12	0.91	0.67	2.11	2.54	2,803,834,624	-30,573,000	-91.71	2.70	1,038,755,968	410,156,992	38.44	-110,861,000	159,237,889	157,430,539	12,012,611	11,281,469	10.37	0.11	3.99	635,027,008	45,047,248	82,842,000	6.70	2.96	860,440,000	-10.82	-2.94	-10.67	82.83	12.78	1.98	0.00	-3.74	-10.30	-32.20	6.54	0.00	1.04	1.03
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALLK	Allakos Inc.	57.49	3,788	104.50	8	2.1	-3.37	-0.48	-18.76	69.96	55.51	157.98	120.84	103.74		0.00	0.00	36.00	135.88	218.00	6,115,939,000	130,646	239,111	248,913	-3.10	-4.55	-33.70	-23.65	-0.72	1.12	1.12	29.35	29.81	4,932,913,152	-155,512,000	-31.72	0.00	0	43,265,000	6.61	-153,480,000	53,117,414	33,579,236	3,205,177	3,142,516	12.07	0.14	12.41	658,996,992	-59,893,624	-113,924,000	12.33	8.48	0	0.00	0.00	0.00	0.00	19.16	2.90	0.00	-15.88	-26.69	0.00	0.00	0.00	6.88	95.94
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALLO	Allogene Therapeutics Inc.	228.99	2,253	32.51	13	1.7	-1.07	-0.95	3.73	0.00	24.85	55.00	34.62	34.58		0.00	0.00	34.00	50.62	71.00	4,751,083,000	593,148	815,635	764,651	-2.08	-2.61	-15.64	-12.57	-0.61	0.86	0.56	8.85	8.96	3,841,934,336	-250,808,000	-15.32	0.00	0	53,783,000	4.98	-250,220,992	140,647,818	73,150,930	10,285,342	11,082,294	10.51	0.12	5.89	827,910,016	-97,894,872	-115,093,000	7.69	4.23	0	0.00	0.00	0.00	0.00	35.89	2.98	0.00	-16.59	-29.29	0.00	0.00	0.00	34.97	64.33
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALNA	Allena Pharmaceuticals Inc.	47.65	3,846	1.12	5	1.8	-1.75	-13.85	-31.29	-10.94	1.07	3.39	1.61	1.47		0.00	0.00	1.00	1.85	1.00	81,337,940	1,298,318	1,188,246	1,627,183	-1.01	-0.95	-1.11	-1.18	0.19	1.54	0.35	5.72	6.08	40,331,836	-31,820,000	-1.27	0.00	0	10,531,000	46.66	-32,845,000	57,279,376	43,847,976	1,361,740	663,917	1.60	0.03	0.62	35,042,000	-16,509,000	-28,159,000	0.44	2.52	0	0.00	0.00	0.00	0.00	38.51	4.25	0.00	-54.74	-165.19	0.00	0.00	0.00	3.32	37.21
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALNY	Alnylam Pharmaceuticals Inc.	139.67	3,099	138.88	20	2.2	-0.10	0.47	-16.71	0.00	119.29	178.41	145.65	141.78		0.00	0.00	88.00	175.25	235.00	15,941,530,000	768,368	555,543	572,817	-7.46	-3.12	-18.61	-44.30	0.32	0.79	0.22	4.23	4.47	14,819,983,360	-793,665,984	-18.67	30.07	492,852,992	521,188,992	51.29	-858,281,024	117,320,127	116,312,877	3,716,221	3,522,894	6.41	0.04	16.02	1,874,395,008	-763,824,768	-614,961,024	8.73	15.91	414,801,000	-168.09	-161.04	-174.15	84.16	9.91	2.14	0.00	-17.85	-69.92	128.20	4.29	0.00	0.55	93.60
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALPN	Alpine Immune Sciences Inc.	760.83	219	11.00	5	1.5	-2.48	-2.91	-14.73	238.89	2.58	16.37	12.00	10.47		0.00	0.00	18.00	21.40	27.00	262,225,900	47,512	118,918	94,723	-1.34	-1.21	-8.20	-8.64	0.83	0.33	1.30	2.57	2.60	187,601,616	-28,171,000	-6.66	20.10	9,335,000	22,598,000	36.36	-27,940,000	23,882,138	8,734,176	644,291	385,513	4.92	0.06	4.42	105,581,000	15,448,500	30,084,000	2.61	4.21	-17,850,000	-307.97	0.00	-299.30	-191.22	134.02	3.99	0.00	-18.13	-60.98	538.30	0.45	0.00	28.16	55.64
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALRN	Aileron Therapeutics Inc.	103.77	3,451	1.21	2	1.7	1.68	-9.70	-41.26	118.35	0.46	2.47	1.60	1.37		0.00	0.00	2.00	3.50	1.59	135,315,800	1,170,932	2,029,032	2,001,251	-0.61	-0.39	-1.99	-3.10	0.06	1.33	1.22	3.49	4.12	93,932,560	-20,333,000	-4.62	0.00	0	387,000	3.18	-21,157,000	90,210,557	80,020,372	1,683,389	1,125,608	0.93	0.02	0.15	13,805,000	-13,609,000	-20,476,000	0.28	4.35	-11,166,000	0.00	0.00	0.00	0.00	41.75	5.31	0.00	-59.84	-150.00	0.00	0.00	0.00	5.80	29.57
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALT	Altimmune Inc.	180.65	2,696	12.27	6	1.7	-3.61	-4.88	-4.96	286.77	2.88	35.10	16.33	15.82		0.00	0.00	8.00	13.31	24.00	514,532,700	1,083,289	1,461,850	2,380,267	-1.91	0.70	-6.41	18.10	0.05	0.41	1.64	18.99	19.16	262,951,856	-38,235,672	-6.88	32.13	8,185,027	1,824,840	0.81	-49,044,476	37,142,946	29,204,359	5,416,115	2,414,375	3.38	0.17	5.84	215,923,360	-25,736,814	-34,436,636	6.11	2.01	-25,324,291	-470.78	-229.59	0.00	100.00	51.12	5.80	0.00	-16.10	-36.14	301.70	0.32	0.00	6.44	61.23
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALXN	Alexion Pharmaceuticals Inc.	224.94	2,298	163.68	15	2.9	3.90	5.59	3.69	0.00	94.82	162.60	153.74	131.36		0.00	0.00	155.00	172.00	190.00	34,048,949,999	7,289,624	2,461,427	2,337,068	2.69	14.39	60.76	10.77	-1.53	0.74	1.28	2.71	3.59	33,989,519,360	3,189,700,096	10.66	5.60	6,069,899,776	2,931,399,936	25.16	603,400,000	219,847,960	218,828,513	7,796,784	7,896,938	2.82	0.04	13.65	2,999,399,936	2,111,137,536	3,002,899,968	53.08	3.08	5,516,400,000	47.47	52.55	9.94	90.88	28.97	1.50	-39.40	10.10	5.26	15.00	27.58	0.00	0.46	91.30
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AMGN	Amgen Inc.	254.41	2,021	255.71	25	2.3	0.23	2.72	1.46	0.00	210.28	276.69	239.39	239.60	2021-05-14	7.04	2.83	185.00	255.77	301.00	146,043,400,000	2,716,196	2,615,453	2,600,416	12.31	18.22	20.76	13.66	-3.99	0.68	0.46	1.37	1.81	166,583,156,736	12,768,000,000	13.05	6.55	25,423,998,976	33,444,999,168	355.46	7,264,000,000	575,802,477	576,463,231	9,876,578	8,712,290	3.85	0.02	18.43	10,647,000,064	9,042,249,728	10,497,000,448	16.27	15.72	19,265,000,000	36.69	50.22	28.57	75.78	8.13	1.19	-3.30	9.51	76.14	7.10	43.39	0.00	0.19	77.65
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AMRN	Amarin Corporation plc	234.34	2,204	5.02	9	2.4	0.20	-15.35	-20.44	0.00	3.36	9.25	6.58	5.83		0.00	0.00	6.00	6.05	10.44	2,385,431,000	4,401,825	6,221,507	7,515,276	-0.05	0.16	-100.40	36.50	3.31	0.88	-0.03	2.13	2.86	1,843,953,280	-17,617,000	-104.67	3.00	614,060,032	10,628,000	1.69	-18,000,000	391,214,481	357,267,486	21,982,259	20,135,782	3.43	0.00	1.27	500,932,992	-19,711,500	-21,746,000	1.60	3.14	482,616,000	-3.20	-2.87	-2.93	78.59	30.49	2.97	-42.40	-1.33	-2.91	16.70	1.61	0.00	1.17	39.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ANAB	AnaptysBio Inc.	230.46	2,239	21.72	4	2.6	-1.59	4.07	-13.47	26.02	13.92	35.85	24.47	22.42		0.00	0.00	19.00	28.50	42.00	580,441,500	257,406	574,194	369,508	-0.73	-3.09	-29.75	-6.64	-0.09	0.64	0.72	19.86	20.01	177,825,872	-23,320,000	-7.63	2.37	75,000,000	342,000	0.09	-19,931,000	27,356,000	14,507,205	4,187,145	3,805,908	5.07	0.23	14.39	393,652,992	-10,647,375	-14,157,000	14.50	1.50	-5,025,000	-31.84	-31.09	-26.58	-6.70	33.91	3.17	0.00	-3.50	-4.97	1,900.00	2.75	0.00	0.77	1.25
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ANIK	Anika Therapeutics Inc.	291.38	1,734	40.21	2	1.0	-1.62	1.03	2.50	0.00	27.54	47.48	37.55	37.49		0.00	0.00	44.00	48.00	52.00	524,464,100	96,914	163,303	122,378	-1.69	0.91	-23.79	43.74	0.15	1.12	0.67	3.32	4.81	494,820,800	14,817,000	33.40	3.79	130,457,000	22,820,000	8.38	-23,982,000	14,329,618	12,669,962	1,336,129	1,399,157	9.20	0.11	6.86	98,318,000	8,322,875	13,065,000	19.01	2.12	80,108,000	1.04	11.36	-18.38	61.41	11.70	2.55	0.00	0.24	-8.55	9.80	9.17	0.00	1.40	97.51
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ANIX	Anixa Biosciences Inc.	463.29	838	4.70	3	2.0	-4.47	4.44	6.10	145.31	1.70	8.09	5.11	3.34		0.00	0.00	8.50	9.50	11.00	158,971,000	636,450	671,645	504,437	-0.41	-0.49	-11.38	-9.39	-0.61	1.07	1.37	9.17	9.55	111,319,864	-9,211,617	-12.09	217.21	512,500	40,836	0.31	-9,634,103	31,431,200	25,626,878	650,478	497,679	0.59	0.02	0.52	13,982,870	-1,590,593	-5,431,713	0.52	9.06	0	-1,803.80	0.00	0.00	24.88	29.85	4.41	0.00	-55.64	-107.41	0.00	0.02	0.00	8.87	5.76
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APLS	Apellis Pharmaceuticals Inc.	304.90	1,635	45.57	14	1.7	1.81	9.65	-5.12	35.69	25.49	58.47	45.08	39.88		0.00	0.00	37.00	64.14	104.00	3,334,774,000	803,822	617,370	654,862	-4.59	-5.31	-9.93	-7.95	-0.63	1.23	0.75	6.84	7.15	2,840,484,096	-213,088,992	-13.33	11.33	250,646,000	377,732,000	184.66	-344,873,984	80,375,365	59,701,214	7,688,392	8,107,904	11.27	0.14	10.92	877,648,000	-53,098,376	-160,488,000	2.69	16.96	-74,325,000	-85.27	-85.02	-137.59	-29.65	14.61	2.94	0.00	-19.79	-288.86	0.00	3.34	0.00	20.13	79.74
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APLT	Applied Therapeutics Inc.	110.31	3,382	16.39	6	1.7	-2.38	-2.15	-18.94	-59.48	13.58	51.99	20.20	22.49		0.00	0.00	27.06	35.00	15.76	516,286,600	49,951	133,650	160,246	-4.28	-4.34	-3.83	-3.83	-2.64	1.41	-0.75	4.58	4.83	333,837,600	0	0.00	0.00	0	2,812,000	3.43	-93,961,000	26,009,399	14,240,666	1,604,397	1,227,332	12.32	0.09	3.72	96,829,000	-43,086,248	-78,209,000	3.64	4.50	0	0.00	0.00	0.00	0.00	21.59	3.89	0.00	-77.23	-164.06	0.00	0.00	0.00	20.68	61.41
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APM	Aptorum Group Limited	0.00	4,019	2.64	0	2.0	3.53	-8.01	-23.48	0.00	1.16	14.23	3.21	2.85		0.00	0.00	0.00	0.00	0.00	99,315,110	119,375	342,005	821,994	-0.54	-0.64	-4.93	-4.38	-0.25	0.26	0.59	1.50	1.99	83,751,888	-16,862,956	-4.97	134.51	622,647	3,174,111	18.12	-15,802,856	11,574,270	7,432,174	216,620	253,830	0.47	0.03	0.14	4,322,373	-6,909,744	-13,073,569	0.65	4.04	-259,379	-2,935.77	0.00	0.00	-38.04	290.27	5.27	0.00	-47.55	-84.08	36.50	0.02	0.00	26.43	1.50
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APRE	Aprea Therapeutics Inc.	223.86	2,310	4.65	4	2.8	7.64	-6.44	-20.78	-86.91	4.26	41.12	5.78	18.61		0.00	0.00	6.00	7.50	10.00	108,052,800	805,564	1,245,717	775,480	-26.67	-1.99	-0.17	-2.23	0.00	0.86	-0.91	5.81	6.03	5,598,850	-52,782,376	-0.11	0.00	0	335,156	0.43	-53,478,812	21,186,827	14,210,640	1,501,997	1,431,182	2.30	0.25	4.20	89,017,688	-22,007,774	-41,802,672	-59.91	-0.08	0	0.00	0.00	0.00	0.00	77.74	3.83	0.00	-29.16	-53.04	0.00	0.00	0.00	23.34	57.50
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APTO	Aptose Biosciences Inc.	26.48	3,967	5.12	1	2.0	-6.57	-2.48	15.84	-31.41	3.39	9.00	4.62	5.08		0.00	0.00	4.72	4.72	4.72	520,200,700	1,298,684	5,177,659	2,204,743	-0.68	-0.54	-7.59	-9.48	0.38	0.87	-0.09	17.97	18.36	365,772,096	-55,616,000	-6.58	0.00	0	1,074,000	0.90	-55,238,000	88,885,238	69,051,386	4,800,280	2,239,853	0.49	0.05	1.38	122,393,000	-13,144,000	-33,891,000	1.34	3.83	0	0.00	0.00	0.00	0.00	66.36	3.25	0.00	-30.75	-51.91	0.00	0.00	0.00	4.61	54.22
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APTX	Aptinyx Inc.	176.20	2,734	2.68	7	1.9	-3.25	-5.97	-33.33	0.00	2.35	6.47	3.37	3.60		0.00	0.00	3.36	3.82	8.00	201,337,800	369,669	398,440	794,964	-1.02	-0.94	-2.62	-3.03	0.32	0.71	0.46	30.83	32.64	49,607,432	-50,344,000	-0.99	31.72	1,564,000	0	0.00	-50,053,000	66,889,600	41,092,303	1,993,931	1,948,764	4.66	0.04	2.11	141,028,000	-24,171,124	-42,356,000	2.31	1.16	-31,271,000	-3,245.84	0.00	0.00	0.00	18.92	3.49	0.00	-24.68	-40.49	-100.00	0.03	0.00	3.18	66.83
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APVO	Aptevo Therapeutics Inc.	626.46	414	25.32	3	1.7	-2.09	-1.29	-23.55	0.00	3.66	60.00	32.25	23.33		0.00	0.00	64.00	65.67	69.00	122,277,800	24,880	50,609	615,216	-5.24	-5.25	-4.84	-4.89	-16.88	2.37	1.85	2.91	3.25	102,530,672	-26,188,000	-3.92	23.80	4,309,000	28,382,000	171.04	-30,923,000	4,449,420	1,895,810	183,582	165,682	3.09	0.04	8.99	39,979,000	-14,253,750	-29,318,000	3.76	6.73	-13,543,000	-638.06	-83.38	-54.92	-23.02	76.11	5.47	0.00	-32.13	-217.49	-93.60	1.27	0.00	5.52	66.59
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARAV	Aravive Inc.	168.79	2,807	5.18	4	1.6	-4.78	-5.65	-8.16	0.00	4.27	14.94	6.80	6.34		0.00	0.00	5.73	7.16	8.28	129,165,300	122,432	261,979	199,223	-1.93	-2.06	-2.68	-2.59	-0.41	1.17	-0.59	6.43	6.52	55,908,632	-23,271,000	-2.40	9.83	5,685,000	8,517,000	17.72	-30,543,000	19,659,860	10,612,786	509,485	560,403	2.26	0.04	3.08	60,541,000	-5,199,000	-12,169,000	2.92	1.78	-11,935,000	-439.75	0.00	0.00	-209.94	22.02	3.73	0.00	-20.86	-52.16	0.00	0.36	0.00	51.85	31.34
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARCT	Arcturus Therapeutics Holdings Inc.	175.76	2,736	40.33	13	2.4	2.05	9.00	-36.76	123.66	17.20	129.71	52.35	57.90		0.00	0.00	31.00	86.15	50.93	1,073,023,999	512,352	783,255	1,128,507	-3.55	7.69	-11.35	5.24	0.04	0.68	1.37	9.39	9.45	596,451,456	-70,642,000	-8.44	62.53	9,539,000	20,750,000	5.23	-72,148,000	26,280,275	21,505,149	3,765,287	3,191,061	4.97	0.18	17.61	462,895,008	-15,130,875	-42,861,000	15.14	2.66	-48,307,000	-749.81	0.00	0.00	0.00	54.68	6.05	0.00	-16.01	-34.17	-24.60	0.47	0.00	18.02	74.89
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARDS	Aridis Pharmaceuticals Inc.	141.70	3,086	5.64	5	2.0	-0.53	0.71	-19.54	-8.75	4.70	10.18	6.52	6.84		0.00	0.00	5.47	7.00	11.00	72,170,360	7,549	37,022	18,679	-2.44	-1.15	-2.32	-4.92	0.04	0.60	0.34	0.38	0.57	58,054,060	-22,064,000	-2.63	58.05	1,000,000	715,000	0.00	-22,333,000	11,227,921	6,844,541	22,370	8,468	0.56	0.00	0.73	8,232,000	-8,815,625	-20,476,000	-0.86	-6.54	-15,956,000	-2,240.10	0.00	0.00	100.00	23.41	3.81	0.00	-64.99	0.00	0.00	0.11	0.00	33.06	12.06
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARDX	Ardelyx Inc.	246.80	2,081	8.69	7	1.4	0.35	16.80	23.26	0.00	4.96	9.23	7.00	6.34		0.00	0.00	11.00	13.86	15.00	616,751,600	3,719,723	1,642,165	845,277	-1.05	-0.67	-8.25	-11.10	0.23	1.37	0.65	6.56	6.85	601,015,168	-88,956,000	-6.76	79.38	7,571,000	53,318,000	42.28	-94,313,000	98,680,264	67,041,398	5,736,878	4,837,039	6.55	0.07	1.89	186,484,000	-46,881,376	-81,435,000	1.35	6.45	-57,627,000	-1,199.05	0.00	0.00	0.00	14.19	2.65	0.00	-24.60	-60.31	-19.60	0.09	0.00	1.32	80.64
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARGX	argenx SE	114.76	3,340	281.72	15	2.1	1.53	1.35	-10.65	93.33	141.26	382.15	315.66	276.57		0.00	0.00	265.12	338.35	430.19	0	148,722	189,191	182,732	-13.96	-15.49	-20.18	-18.19	-1.84	0.81	1.52	6.10	6.26	12,616,667,136	-419,464,992	-30.08	231.35	54,534,000	7,868,000	0.58	-528,923,008	50,935,679	49,528,897	1,066,614	981,521	5.20	0.00	31.71	1,626,968,064	-74,803,000	-346,348,992	28.68	9.82	-270,945,000	-770.73	0.00	0.00	0.00	33.91	2.09	0.00	-15.96	-43.80	-44.20	1.20	0.00	0.00	50.73
HEALTH CARE	Biotechnology	Biotechnology	AMEX	ARMP	Armata Pharmaceuticals Inc.	468.83	817	4.10	4	1.7	-0.73	-11.26	21.66	0.00	2.56	10.48	5.30	3.89		0.00	0.00	7.00	7.75	9.00	121,958,800	9,671	29,072	29,788	-1.35	-1.15	-3.03	-3.75	0.20	0.13	0.76	1.52	1.62	118,725,840	-20,473,000	-5.80	144.26	823,000	13,150,000	69.74	-22,181,000	24,940,442	9,282,583	53,880	55,676	1.91	0.01	0.39	9,649,000	-9,833,375	-18,270,000	1.01	4.06	-11,721,000	-2,622.97	0.00	0.00	0.00	37.63	3.00	0.00	-41.54	-132.62	0.00	0.05	0.00	75.38	8.60
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARNA	Arena Pharmaceuticals Inc.	207.94	2,448	65.90	13	1.7	-3.07	-0.59	-14.04	40.77	44.79	90.19	74.48	72.47		0.00	0.00	76.00	97.23	120.00	4,217,392,000	682,393	505,862	589,278	-7.39	-7.37	-8.92	-9.18	32.95	0.99	0.82	19.01	19.62	2,959,691,520	-422,780,992	-7.00	9,278.03	319,000	57,512,000	5.32	-404,734,016	60,334,648	55,996,587	3,783,767	3,479,987	6.39	0.06	18.30	1,104,040,960	-210,402,256	-353,094,016	18.44	3.57	-323,421,000	-133,742.64	62.07	49.30	100.00	19.77	2.15	0.00	-22.55	-37.62	-98.80	0.01	0.00	0.31	91.82
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARWR	Arrowhead Pharmaceuticals Inc.	141.79	3,085	67.65	12	2.0	-0.49	8.85	-15.46	92.85	30.83	92.60	73.95	61.53		0.00	0.00	34.00	91.17	106.00	6,533,732,000	632,069	807,074	1,115,948	-1.01	-0.54	-67.31	-125.89	1.45	1.25	1.20	12.53	12.90	6,687,277,056	-105,829,536	-63.19	83.76	79,840,064	20,868,000	4.59	-102,612,224	103,792,410	100,461,712	4,869,150	5,143,235	5.36	0.06	2.94	305,327,008	-90,661,632	-110,783,568	4.40	15.36	87,992,066	-140.73	-132.55	-128.52	100.00	39.99	2.98	0.00	-12.92	-21.51	-27.70	0.78	0.00	3.20	67.40
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ASLN	ASLAN Pharmaceuticals Limited	349.15	1,354	3.01	2	2.3	-2.59	-10.15	40.65	61.58	1.26	6.75	3.64	2.27		0.00	0.00	8.00	8.50	9.00	201,077,200	296,242	2,647,623	887,358	-1.16	-0.59	-2.59	-5.17	0.05	0.56	1.20	1.94	2.00	134,410,640	-17,967,856	-7.48	708.51	189,710	18,710,968	0.00	-42,901,896	264,954,970	37,990,614	1,318,009	8,711	0.30	0.00	0.32	12,060,285	-9,711,812	-16,768,068	-0.32	-9.50	79,821,000	-9,498.70	0.00	0.00	95.78	26.34	3.69	0.00	-49.34	-5,313.82	0.00	0.01	0.00	0.00	11.39
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ASMB	Assembly Biosciences Inc.	222.85	2,320	4.28	5	2.0	-1.16	-1.84	-27.95	-73.63	4.11	27.84	5.08	11.77		0.00	0.00	4.77	6.00	11.40	170,960,000	518,171	1,382,480	909,838	-1.75	-2.96	-2.44	-1.46	-0.04	1.22	-0.90	8.91	9.19	-36,853,812	-60,101,000	0.61	-0.47	79,105,000	10,129,000	4.21	-62,152,000	40,059,122	33,873,416	4,228,194	3,866,813	3.07	0.11	5.66	216,412,992	-12,025,000	-62,957,000	7.07	0.61	-22,232,000	-76.85	-75.98	-78.57	-28.10	69.07	2.75	0.00	-12.19	-24.19	-78.20	2.23	0.00	1.68	68.70
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ASND	Ascendis Pharma A/S	248.68	2,061	121.95	12	1.6	-1.80	-2.91	-21.25	0.00	120.02	183.98	143.07	152.26		0.00	0.00	167.42	194.58	216.54	7,031,088,000	307,219	225,484	191,593	-9.85	-7.26	-12.38	-16.99	0.47	0.40	0.03	13.75	14.02	6,124,766,208	-328,028,992	-18.67	880.88	6,953,000	91,975,000	10.97	-418,955,008	53,750,386	43,772,164	2,853,637	2,212,085	13.69	0.00	13.37	718,795,008	-171,163,248	-271,548,000	15.60	7.82	6,953,000	-4,755.07	0.00	0.00	100.00	8.17	1.76	0.00	-24.95	-58.36	-78.70	0.14	0.00	0.03	1.03
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ATHX	Athersys Inc.	129.98	3,191	1.69	4	1.7	-1.74	-5.06	-7.65	-16.91	1.53	3.39	2.05	2.09		0.00	0.00	4.00	1.67	2.23	359,458,300	1,672,303	3,053,000	2,514,898	-0.42	-0.10	-4.02	-16.90	0.05	1.17	0.24	2.25	2.38	319,352,544	-77,442,000	-4.12	221.77	1,440,000	678,000	2.16	-78,765,000	215,244,507	196,408,460	26,040,188	22,003,237	8.57	0.13	0.24	51,546,000	-33,099,500	-61,810,000	0.16	10.90	-61,554,000	-5,439.72	0.00	0.00	0.00	31.29	4.08	0.00	-96.58	-288.34	342.50	0.01	0.00	8.73	25.48
HEALTH CARE	Biotechnology	Biotechnology	AMEX	ATNM	Actinium Pharmaceuticals Inc. (Delaware)	114.08	3,346	7.46	4	1.8	-1.45	-8.24	-10.55	17.36	4.71	19.47	8.45	10.03		0.00	0.00	7.96	11.70	5.70	114,262,700	185,298	338,209	474,267	-1.83	-1.02	-4.07	-7.31	0.09	0.87	0.63	13.33	13.62	82,867,480	-21,946,000	-3.78	0.00	0	738,000	1.20	-22,216,000	19,245,638	18,904,413	937,651	803,265	3.01	0.05	3.30	63,560,000	-13,336,625	-21,617,000	3.50	2.13	0	0.00	0.00	0.00	0.00	39.63	3.80	0.00	-35.86	-66.35	0.00	0.00	0.00	1.61	17.11
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ATNX	Athenex Inc.	260.88	1,973	3.97	6	2.4	-3.64	-3.17	-65.48	0.00	3.76	15.24	7.23	10.93		0.00	0.00	5.00	5.73	10.50	424,284,300	1,616,389	3,681,312	1,485,499	-1.72	-1.23	-2.31	-3.33	0.08	0.85	-0.40	3.81	4.70	318,641,280	-119,231,000	-2.67	2.21	144,391,008	158,127,008	95.63	-146,179,008	93,454,700	62,444,561	6,300,792	6,266,201	1.07	0.09	2.23	208,223,008	-105,002,752	-131,243,000	1.93	2.06	49,036,000	-85.69	-82.58	-101.24	33.96	54.66	3.37	0.00	-22.28	-87.01	-36.50	1.70	0.00	19.45	55.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ATOS	Atossa Therapeutics Inc.	83.67	3,601	1.63	2	2.0	-5.78	-19.31	-2.40	-16.43	0.81	5.08	2.65	2.37		0.00	0.00	1.59	2.03	2.47	260,980,599	5,431,074	14,441,040	8,975,126	-1.98	-0.21	-0.83	-7.76	0.01	1.39	0.45	2.56	2.73	170,111,536	-14,560,872	-11.68	0.00	0	18,053	0.07	-22,330,752	120,824,368	120,796,578	10,037,034	7,055,498	0.82	0.08	0.33	39,553,672	6,818,665	-11,570,282	0.56	2.92	0	0.00	0.00	0.00	0.00	59.44	5.44	0.00	-31.85	-88.42	0.00	0.00	0.00	0.04	7.59
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ATRA	Atara Biotherapeutics Inc.	192.61	2,579	13.28	7	1.9	-4.74	-3.56	-27.55	68.49	7.45	28.20	16.24	16.43		0.00	0.00	10.00	24.83	35.57	1,237,500,000	629,675	819,406	879,668	-4.15	-3.62	-3.20	-3.85	0.25	1.21	0.94	6.05	6.31	672,581,696	-300,641,984	-2.24	0.00	0	15,175,000	3.28	-306,620,000	83,614,853	59,497,821	13,115,910	11,103,813	13.52	0.18	5.99	500,659,008	-100,886,496	-180,759,008	5.55	2.39	0	0.00	0.00	0.00	0.00	28.70	3.21	0.00	-41.49	-81.43	0.00	0.00	0.00	1.25	1.06
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AUPH	Aurinia Pharmaceuticals Inc	160.14	2,912	12.35	7	1.7	-1.98	-3.52	-18.70	-21.15	12.01	20.50	13.92	14.42		0.00	0.00	9.00	11.50	14.00	0	1,438,933	3,217,314	2,499,267	-0.87	-0.55	-14.24	-22.45	0.39	0.80	-0.14	12.48	13.11	1,215,958,272	-102,919,000	-11.82	24.26	50,118,000	8,407,000	2.06	-102,680,000	127,450,815	116,019,751	8,141,978	5,953,855	2.23	0.00	3.13	398,328,992	-45,765,248	-69,858,000	3.22	3.84	-209,000	-208.09	-205.35	-204.88	-0.42	26.13	2.52	0.00	-16.54	-29.07	172,417.20	0.42	0.00	7.24	50.64
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AUTL	Autolus Therapeutics plc	242.92	2,128	5.29	9	2.2	-4.51	-5.54	-37.02	-33.74	5.10	17.19	6.50	10.62		0.00	0.00	7.00	8.91	15.78	423,748,900	418,733	970,493	361,744	-1.40	-1.85	-3.78	-3.00	-0.12	1.14	-0.49	10.32	11.05	3,003,150	-68,942,608	-0.04	2.79	1,078,500	0	0.00	-53,279,500	66,584,591	33,904,120	3,844,819	3,508,974	5.34	0.00	5.52	217,450,000	0	0	5.91	0.90	-133,173,000	-6,570.75	0.00	0.00	0.00	13.98	3.23	0.00	-22.28	-29.62	0.00	0.03	0.00	25.58	18.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AVEO	AVEO Pharmaceuticals Inc.	408.72	1,054	6.21	4	1.2	-1.43	-8.94	-25.45	0.00	3.60	18.24	8.58	6.42		0.00	0.00	7.24	8.59	18.00	243,660,800	1,145,615	3,042,776	1,067,691	-1.66	-0.17	-3.73	-40.12	0.04	0.69	0.85	3.72	3.87	137,743,200	-38,856,000	-3.55	22.89	6,019,000	14,477,000	41.02	-35,584,000	34,360,800	23,911,373	2,203,336	911,893	0.39	0.09	2.28	61,761,000	-20,275,500	-37,983,000	1.31	4.73	-16,660,000	-645.91	0.00	-13.28	-276.79	88.89	3.87	0.00	-41.35	-141.94	16.00	0.28	0.00	0.13	33.49
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AVRO	AVROBIO Inc.	52.25	3,821	10.35	7	2.1	-10.00	-8.57	-26.28	-10.39	10.25	23.50	12.58	14.88		0.00	0.00	14.00	18.46	10.46	498,632,300	386,457	800,803	393,336	-3.31	-3.09	-3.13	-3.72	0.48	1.17	0.07	15.79	16.09	206,887,856	-119,021,000	-1.74	0.00	0	0	0.00	-119,712,000	41,622,060	33,496,054	4,025,924	3,313,236	5.50	0.11	6.24	259,682,000	-55,789,500	-98,803,000	6.12	1.69	0	0.00	0.00	0.00	0.00	27.87	3.51	0.00	-31.86	-54.37	0.00	0.00	0.00	3.08	98.40
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AVXL	Anavex Life Sciences Corp.	163.92	2,880	11.80	5	1.7	-2.64	-19.12	105.22	0.00	3.01	28.70	13.72	7.17		0.00	0.00	10.00	15.20	20.00	1,039,538,000	1,172,016	4,574,989	2,014,988	-0.46	-0.55	-25.93	-26.53	-1.24	1.24	1.75	6.71	6.76	966,470,144	0	0.00	0.00	0	0	0.00	-27,543,610	69,487,904	67,157,229	3,603,186	4,006,149	1.86	0.05	0.68	47,357,600	-13,442,241	-23,433,264	0.69	17.08	0	0.00	0.00	0.00	0.00	42.59	4.21	0.00	-40.93	-76.23	0.00	0.00	0.00	3.50	20.53
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AXLA	Axcella Health Inc.	73.10	3,666	4.25	9	1.8	-0.24	-2.07	-25.83	21.71	3.34	7.73	5.44	5.19		0.00	0.00	8.00	4.84	2.80	183,552,400	102,226	80,983	138,005	-1.78	-2.28	-2.39	-1.86	-0.09	1.07	0.65	13.79	14.01	78,454,256	-53,417,000	-1.47	0.00	0	25,222,000	33.46	-56,527,000	37,690,435	17,094,497	401,269	376,560	5.18	0.03	2.85	107,329,000	-29,836,876	-49,771,000	2.01	2.12	0	0.00	0.00	0.00	0.00	24.92	3.71	0.00	-33.00	-83.37	0.00	0.00	0.00	17.33	67.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AZRX	AzurRx BioPharma Inc.	67.29	3,713	0.79	3	2.2	-2.47	-15.05	-36.29	0.00	0.57	2.63	1.35	1.00		0.00	0.00	0.80	1.11	1.59	93,018,980	1,592,017	4,235,726	3,331,803	-1.47	-0.18	-0.54	-5.17	0.01	0.69	0.67	0.43	0.51	63,795,424	-25,867,424	-2.47	0.00	0	628,945	0.75	-41,732,336	74,439,377	72,999,719	669,092	2,273,741	0.21	0.01	0.08	6,062,141	-633,837	-11,221,538	-0.09	-9.29	0	0.00	0.00	0.00	0.00	48.31	4.20	0.00	-151.38	-3,305.91	0.00	0.00	0.00	1.03	2.61
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BBIO	BridgeBio Pharma Inc.	360.07	1,304	55.12	9	1.8	0.31	1.16	-17.04	0.00	26.17	73.50	63.85	48.56		0.00	0.00	75.00	84.22	91.00	9,059,524,000	507,717	951,228	765,235	-4.73	-2.36	-11.66	-23.09	0.23	0.87	1.48	6.35	6.72	7,925,429,248	0	0.00	960.78	8,249,000	497,488,000	461.12	-448,724,000	148,956,329	77,904,471	11,489,113	11,334,727	10.66	0.15	4.14	607,092,992	-248,651,632	-399,713,984	3.92	14.07	8,249,000	-5,751.99	0.00	0.00	100.00	16.86	2.78	0.00	-44.42	-173.15	-99.10	0.07	0.00	5.47	79.57
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCDA	BioCardia Inc.	124.10	3,253	3.98	4	2.0	-3.40	-8.30	-9.34	29.97	1.91	8.60	4.27	3.13		0.00	0.00	5.00	10.63	6.05	59,461,960	150,478	207,115	1,312,922	-1.48	-0.91	-2.68	-4.37	0.07	0.32	0.73	5.24	5.33	46,523,932	-15,461,000	-3.01	320.86	145,000	614,000	3.20	-15,004,000	16,339,061	10,665,812	458,311	217,287	3.03	0.04	1.31	21,407,000	-6,520,500	-12,357,000	1.18	3.38	-9,668,000	-10,709.66	0.00	0.00	0.00	58.76	4.28	0.00	-62.41	-139.27	-78.60	0.01	0.00	38.32	11.11
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCEL	Atreca Inc.	327.76	1,493	11.81	9	1.5	-3.51	-3.91	-20.74	-32.54	11.01	25.03	16.04	15.22		0.00	0.00	25.00	30.22	35.00	451,133,400	168,063	280,788	253,392	-6.36	-2.60	-1.86	-4.78	0.03	1.10	0.01	14.05	14.30	188,314,352	-86,502,000	-2.18	0.00	0	53,000	0.02	-86,335,000	30,173,414	18,508,024	4,834,326	3,413,169	18.85	0.22	6.52	240,084,992	-41,837,876	-66,671,000	7.33	1.61	0	0.00	0.00	0.00	0.00	20.19	3.50	0.00	-23.75	-40.25	0.00	0.00	0.00	3.63	92.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCLI	Brainstorm Cell Therapeutics Inc.	51.80	3,824	3.13	2	2.5	-2.49	-14.25	-42.46	0.00	3.10	17.95	4.59	9.01		0.00	0.00	3.50	3.66	3.82	137,527,500	624,947	1,108,609	1,001,810	-1.07	-0.92	-2.94	-3.97	0.21	1.35	0.17	3.76	3.85	95,664,216	-31,465,000	-3.04	0.00	0	7,217,000	20.35	-31,811,000	35,721,429	31,544,522	4,218,074	4,224,050	3.77	0.14	1.17	41,936,000	-23,808,876	-35,193,000	1.01	3.10	0	0.00	0.00	0.00	0.00	66.14	4.37	0.00	-68.53	-273.75	0.00	0.00	0.00	18.19	23.13
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCRX	BioCryst Pharmaceuticals Inc.	177.25	2,723	11.24	9	2.0	-0.88	10.09	22.84	0.00	2.75	14.24	10.99	6.73		0.00	0.00	9.00	14.56	19.00	1,833,841,000	3,297,322	6,299,076	6,564,196	-1.09	-0.74	-10.28	-13.80	0.32	1.34	1.75	2.93	3.07	1,788,171,904	-174,008,992	-10.28	100.39	17,812,000	279,502,016	240.14	-182,814,000	177,182,751	162,861,069	26,681,807	28,863,457	3.96	0.16	1.70	300,366,016	-74,047,248	-137,216,000	-0.11	-103.12	-106,828,000	-981.12	-227.40	-233.45	-121.50	38.15	4.23	0.00	-42.83	-1,925.37	-89.90	0.11	0.00	0.93	69.76
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCYC	Bicycle Therapeutics plc	439.54	914	29.45	8	1.6	-1.74	3.77	8.51	104.92	12.54	33.20	27.23	21.34		0.00	0.00	30.00	36.75	58.00	557,529,100	75,730	173,810	108,050	-4.99	-2.06	-5.90	-14.55	0.10	0.61	1.31	6.51	6.73	571,572,864	-50,683,000	-11.28	55.01	10,390,000	15,775,000	16.53	-51,010,000	23,090,382	13,524,037	430,990	400,080	3.20	0.00	5.89	135,990,000	-19,769,624	-17,789,000	5.33	5.53	-22,759,000	-500.10	0.00	0.00	-219.05	28.06	3.14	0.00	-23.94	-54.08	-27.10	0.54	0.00	12.67	50.19
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BFRA	Biofrontera AG	0.00	4,019	5.37	2	2.0	-2.72	-4.11	-34.27	-12.38	4.67	55.00	6.37	7.77		0.00	0.00	7.00	8.00	9.00	0	39,910	72,379	285,537	-0.58	-0.94	-9.32	-5.76	-0.15	1.12	0.69	2.48	3.15	190,924,496	-2,278,000	-83.81	6.29	30,346,000	23,875,000	323.73	-13,023,000	56,717,385	20,573,134	2,714	14,460	0.04	0.00	0.51	17,077,000	-3,436,875	-2,849,000	0.22	24.19	26,810,000	-25.08	-7.51	-42.92	88.35	378.63	5.21	0.00	-8.29	-150.29	-22.00	1.12	0.00	0.00	0.06
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BGNE	BeiGene Ltd.	157.98	2,935	305.54	15	2.3	-0.74	-0.89	-14.41	0.00	136.48	388.97	331.11	281.59		0.00	0.00	170.18	346.22	509.20	31,045,740,000	165,197	271,399	329,092	-19.13	-14.36	-15.97	-21.47	0.64	0.68	1.56	4.40	4.61	24,149,342,208	-1,625,892,992	-14.85	78.19	308,873,984	561,964,032	14.52	-1,596,905,984	1,192,115,784	47,522,956	2,570,203	2,203,406	7.81	0.00	50.77	4,650,675,200	-752,288,128	-1,283,460,992	42.24	7.23	-1,056,660,000	-536.69	-282.51	-284.45	-179.14	10.94	2.31	0.00	-28.73	-66.03	75.90	3.70	0.00	20.48	63.48
HEALTH CARE	Biotechnology	Biotechnology	NYSE	BHVN	Biohaven Pharmaceutical Holding Company Ltd.	335.32	1,456	74.40	11	1.7	-1.89	7.22	-4.42	97.42	34.78	100.77	77.03	76.66		0.00	0.00	73.00	101.91	125.00	4,200,854,000	319,287	642,691	572,385	-13.06	-5.73	-5.70	-12.98	0.10	1.14	1.47	1.72	2.18	4,857,048,576	-635,940,992	-7.64	76.34	63,627,000	459,153,984	0.00	-766,796,032	64,619,077	54,308,509	5,910,618	5,756,718	7.54	0.10	5.74	355,334,016	-530,157,120	-702,878,976	-6.46	-11.52	45,933,000	-1,014.33	0.00	0.00	72.19	11.45	2.65	0.00	-78.23	0.00	0.00	1.08	0.00	13.27	91.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BIIB	Biogen Inc.	236.92	2,184	270.31	29	2.7	-0.05	0.80	0.07	-18.58	223.25	363.92	271.06	269.24		0.00	0.00	166.00	290.28	458.00	42,140,630,000	1,000,008	1,155,227	1,366,837	24.45	20.15	11.05	13.19	-0.15	0.79	-0.10	1.32	1.84	45,837,348,864	5,112,500,224	8.97	3.41	13,444,599,808	7,911,399,936	74.03	4,000,600,064	150,554,556	151,278,521	3,648,377	3,571,963	2.84	0.02	17.13	2,610,099,968	2,880,375,040	4,229,799,936	70.21	3.85	11,639,400,000	34.63	38.03	29.76	86.57	44.06	1.69	-71.20	11.22	33.80	-22.30	83.56	0.00	0.64	86.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BIOC	Biocept Inc.	233.83	2,211	4.36	1	2.0	-0.68	-5.22	-30.46	0.00	3.46	13.00	5.88	5.77		0.00	0.00	6.37	6.37	6.37	114,191,700	137,468	536,834	950,856	-1.50	-0.80	-2.90	-5.75	0.06	0.86	0.49	2.28	2.61	59,511,588	-14,383,021	-4.14	2.17	27,461,398	12,228,637	51.61	-17,809,678	13,402,400	13,400,090	574,308	376,845	1.49	0.04	1.07	14,367,942	-14,752,468	-19,787,100	1.77	2.47	6,124,607	-56.33	-52.38	-64.84	22.30	46.18	4.77	0.00	-29.66	-102.07	937.80	2.32	0.00	0.02	9.57
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BLCM	Bellicum Pharmaceuticals Inc.	44.56	3,870	3.20	1	3.0	-5.88	-10.86	-25.75	0.00	2.62	9.56	4.33	5.04		0.00	0.00	4.50	4.50	4.50	20,036,720	137,475	550,153	396,739	-1.34	-2.93	-2.39	-1.23	-0.02	1.30	-0.14	1.44	1.60	13,572,600	-52,611,000	-0.26	27.15	500,000	1,169,000	7.52	-7,722,000	8,318,273	7,360,174	862,982	603,899	1.72	0.14	4.27	35,495,000	-70,843,752	-56,650,000	-0.30	-10.67	-38,552,000	-10,816.60	0.00	0.00	100.00	36.92	4.80	0.00	-43.11	-143.13	-90.30	0.09	0.00	0.20	27.58
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BLRX	BioLineRx Ltd.	94.83	3,523	2.63	3	1.7	-1.50	-8.36	3.95	53.45	1.40	4.23	3.10	2.38		0.00	0.00	5.00	3.61	1.90	0	451,241	1,055,740	2,571,862	-1.79	-0.80	-1.47	-3.29	0.03	0.58	0.91	2.14	2.15	47,249,180	-22,348,000	-2.11	0.00	0	7,684,000	34.88	-30,021,000	641,884,092	23,018,653	413,394	675,359	0.71	0.00	0.97	22,587,000	-13,736,125	-23,206,000	0.95	2.78	0	0.00	0.00	0.00	0.00	33.58	3.82	0.00	-28.42	-108.36	0.00	0.00	0.00	0.00	15.16
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BLUE	bluebird bio Inc.	137.51	3,121	28.28	17	2.4	-4.85	0.43	-39.62	0.00	24.24	72.51	31.90	48.13		0.00	0.00	27.00	27.37	48.06	2,012,889,000	2,440,943	2,629,996	1,363,862	-9.95	-9.67	-2.84	-2.91	1.01	0.74	-0.64	5.78	5.97	932,461,824	-610,158,016	-1.53	3.72	250,734,000	193,020,992	14.25	-618,694,976	67,141,044	66,450,834	5,409,009	6,086,312	1.28	0.12	17.15	1,151,250,944	-289,858,240	-470,351,008	20.40	1.39	-342,618,000	-251.07	-243.35	-246.75	-136.65	37.65	2.69	0.00	-22.43	-46.87	7.10	4.03	0.00	0.93	85.37
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BMRN	BioMarin Pharmaceutical Inc.	650.27	356	79.40	18	2.0	0.80	3.02	-8.61	-11.61	71.35	131.95	79.43	86.96		0.00	0.00	84.00	108.56	183.00	13,724,500,000	867,973	1,177,243	1,666,641	4.53	1.01	17.55	78.61	0.37	0.79	0.04	3.07	4.76	14,388,725,760	13,412,000	1,072.83	7.73	1,860,455,040	1,131,388,032	27.55	859,100,032	181,829,680	180,467,776	11,205,928	11,409,128	8.49	0.07	5.86	1,065,385,984	-85,928,128	85,365,000	22.59	3.51	708,067,000	-4.93	0.72	46.18	38.06	35.24	1.73	-21.80	-1.09	23.77	-0.50	10.29	0.00	0.62	1.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BNTC	Benitec Biopharma Inc.	23.19	3,978	4.64	0	3.0	-2.11	-6.64	16.58	0.00	2.30	17.39	4.29	4.70		0.00	0.00	0.00	0.00	0.00	23,247,200	254,550	3,332,304	1,046,161	-5.80	-3.44	-0.80	-1.44	0.02	0.30	0.66	18.01	18.46	8,867,131	-10,752,000	-0.83	184.73	48,000	311,000	2.13	-11,007,000	4,540,469	3,510,464	44,353	35,186	0.11	0.01	3.09	14,010,000	-5,338,510	-9,600,000	3.22	1.44	287,000	-22,816.67	22.53	23.99	162.10	190.36	5.70	0.00	-42.95	-73.62	-98.70	0.03	0.00	21.02	14.75
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BPMC	Blueprint Medicines Corporation	308.69	1,609	95.20	13	2.0	-0.78	1.11	-4.67	38.95	56.00	125.61	98.07	94.06		0.00	0.00	81.00	116.31	152.00	5,602,765,000	236,234	414,808	463,916	5.25	-5.26	18.13	-17.70	-0.09	1.11	0.87	6.86	7.09	4,675,046,400	315,265,984	14.83	5.89	793,734,976	89,604,000	6.10	313,881,984	57,957,641	57,568,166	3,133,547	3,004,457	6.60	0.06	15.04	871,849,024	272,397,888	387,035,008	25.44	3.74	466,450,000	38.89	39.72	39.55	58.77	17.45	2.27	0.00	15.91	32.45	-33.80	14.56	0.00	0.99	1.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BPTH	Bio-Path Holdings Inc.	262.63	1,962	5.58	2	2.0	-5.26	-18.42	28.87	16.86	3.12	24.34	6.89	4.88		0.00	0.00	12.00	12.50	13.00	48,010,070	294,910	2,999,452	1,161,308	-2.83	-1.97	-1.97	-2.99	0.06	0.80	0.58	11.77	13.65	29,443,618	-10,836,000	-2.72	0.00	0	330,000	2.19	-10,882,000	6,947,912	6,901,500	75,517	111,802	0.18	0.01	1.98	13,755,000	-6,810,500	-10,960,000	3.32	1.68	0	0.00	0.00	0.00	0.00	126.31	4.12	0.00	-34.84	-60.20	0.00	0.00	0.00	0.67	7.09
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BTAI	BioXcel Therapeutics Inc.	195.29	2,551	34.95	11	1.6	-0.14	-2.57	-27.29	0.00	25.92	71.50	46.95	47.88		0.00	0.00	33.48	55.70	63.00	1,021,007,000	261,868	524,939	566,863	-3.79	-3.25	-9.22	-11.04	0.65	1.47	0.62	18.00	18.33	669,948,160	-80,956,000	-8.28	0.00	0	1,635,000	0.79	-82,169,000	24,572,962	15,270,376	3,707,133	3,568,899	7.63	0.25	8.67	213,119,008	-35,376,876	-66,350,000	8.47	4.13	0	0.00	0.00	0.00	0.00	16.16	3.93	0.00	-39.57	-70.35	0.00	0.00	0.00	38.70	55.42
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BYSI	BeyondSpring Inc.	242.34	2,136	9.80	4	1.6	-2.58	-4.76	-25.31	-18.57	9.62	21.50	12.40	12.87		0.00	0.00	10.58	13.69	25.00	436,040,900	180,996	236,795	261,697	-2.03	-2.39	-4.82	-4.21	-0.27	0.84	0.09	2.41	2.78	278,740,672	-60,811,000	-4.58	0.00	0	4,351,000	18.98	-57,450,000	39,141,913	16,066,580	1,252,725	1,199,470	5.72	0.05	1.01	30,874,000	-26,588,500	-49,465,000	0.79	12.44	0	0.00	0.00	0.00	0.00	24.32	3.41	0.00	-103.49	-267.71	0.00	0.00	0.00	71.55	16.86
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CABA	Cabaletta Bio Inc.	329.39	1,483	10.70	4	2.0	-0.47	-0.56	-16.14	0.00	6.15	16.38	11.48	12.16		0.00	0.00	20.00	22.25	28.00	260,599,900	68,987	103,588	98,132	-10.97	-1.94	-0.98	-5.55	0.01	1.26	0.96	20.98	21.92	150,253,456	-33,479,000	-4.49	0.00	0	0	0.00	-33,339,000	24,062,775	7,915,450	1,715,182	1,608,540	13.85	0.09	4.52	108,662,000	-15,530,625	-26,770,000	-6.78	-1.58	0	0.00	0.00	0.00	0.00	19.19	3.50	0.00	-16.51	-26.90	0.00	0.00	0.00	5.08	66.36
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CALA	Calithera Biosciences Inc.	121.04	3,281	2.15	5	1.7	-2.27	-8.51	-26.62	0.00	2.08	7.42	2.75	3.81		0.00	0.00	2.00	3.18	5.00	181,093,100	612,009	1,030,282	969,498	-1.31	-0.95	-1.64	-2.47	0.06	0.90	-1.09	6.34	6.45	63,862,068	-91,023,000	-0.70	0.00	0	6,718,000	6.56	-90,137,000	73,317,051	64,260,196	1,816,623	3,002,450	1.52	0.04	1.57	115,151,000	-51,518,876	-84,312,000	1.45	1.48	-71,015,000	-146.77	-145.01	-141.02	65.46	44.34	2.86	0.00	-38.81	-73.64	0.00	0.00	0.00	0.98	79.01
HEALTH CARE	Biotechnology	Biotechnology	AMEX	CANF	Can-Fite Biopharma Ltd	53.30	3,814	2.09	0	2.0	-4.13	-12.19	5.56	17.84	1.51	4.39	2.30	2.04		0.00	0.00	0.00	0.00	0.00	0	404,911	4,839,495	1,830,779	-1.20	-0.63	-1.74	-3.32	0.04	0.51	0.56	6.59	7.41	30,748,802	-14,127,000	-2.18	40.30	763,000	67,000	1.10	-14,443,000	515,746,293	16,534,482	895,239	335,651	0.10	0.00	0.49	8,343,000	-7,405,750	-12,063,000	0.39	5.36	763,000	-1,853.08	0.00	0.00	100.00	43.09	3.60	0.00	-99.87	-339.20	-21.90	0.06	0.00	1.07	11.25
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CAPR	Capricor Therapeutics Inc.	0.00	4,019	4.01	1	2.0	-0.25	-8.66	-25.60	176.87	1.40	12.32	5.63	5.25		0.00	0.00	12.00	12.00	12.00	116,041,500	316,886	438,737	1,329,881	-0.88	-1.06	-4.56	-3.79	-0.22	0.90	1.02	11.01	11.33	60,550,496	-13,546,081	-4.47	195.17	310,250	428,795	1.52	-13,657,028	22,797,930	20,281,267	939,459	345,150	2.44	0.04	1.43	32,665,874	-5,643,157	-10,054,810	1.37	2.93	-8,146,750	-4,412.56	0.00	0.00	0.00	252.08	5.99	0.00	-37.42	-77.95	-74.00	0.02	0.00	2.27	15.31
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CASI	CASI Pharmaceuticals Inc.	605.36	462	1.79	2	1.5	-1.11	-11.82	-44.92	-2.08	1.46	3.90	2.44	2.26		0.00	0.00	3.50	4.25	5.00	287,982,800	921,229	1,437,180	719,042	-0.44	-0.28	-4.10	-6.79	0.11	0.93	0.41	8.90	9.28	242,644,896	-31,354,000	-7.74	16.03	15,141,000	3,196,000	3.09	-48,287,000	139,797,487	95,655,033	2,086,033	1,755,385	1.07	0.02	0.48	66,373,000	-25,866,188	-25,886,000	0.66	2.72	5,633,000	-220.02	-207.08	0.00	37.20	21.75	3.34	0.00	-18.08	-48.18	258.80	0.14	0.00	31.02	29.85
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CATB	Catabasis Pharmaceuticals Inc.	70.75	3,689	2.24	1	2.0	-5.49	-17.34	-18.25	0.00	1.25	8.59	3.06	4.13		0.00	0.00	5.00	5.00	5.00	67,440,980	771,663	1,225,303	3,632,199	-2.03	-0.64	-1.10	-4.23	0.02	0.45	0.07	7.03	7.25	19,576,086	-37,009,000	-0.53	0.00	0	1,046,000	2.57	-37,300,000	23,417,006	20,370,454	2,726,339	2,386,081	1.80	0.13	1.92	44,930,000	-18,537,876	-32,485,000	2.03	1.11	0	-12,122.00	0.00	0.00	100.00	71.02	4.01	0.00	-51.88	-97.66	0.00	0.00	0.00	0.11	48.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CBIO	Catalyst Biosciences Inc.	243.35	2,125	4.74	5	2.0	-1.46	-7.24	-28.83	0.00	4.05	8.22	5.79	5.65		0.00	0.00	4.77	5.67	7.96	161,354,800	239,057	520,663	328,514	-2.93	-3.03	-1.62	-1.59	-0.48	0.84	0.24	4.65	5.03	78,945,136	-56,432,000	-1.40	3.77	20,948,000	1,644,000	2.16	-56,241,000	31,331,027	26,271,379	1,000,603	733,330	2.66	0.03	2.53	79,354,000	-34,096,248	-55,048,000	3.44	1.38	-40,390,000	-270.05	-269.39	-268.48	-192.81	23.68	2.95	0.00	-36.56	-77.89	0.00	1.09	0.00	3.24	56.15
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CBPO	China Biologic Products Holdings Inc.	47.18	3,851	118.00	4	3.0	-0.05	0.00	-0.42	0.00	99.74	120.01	118.27	114.09		0.00	0.00	77.00	102.78	119.00	4,585,141,000	59,019	143,554	125,272	3.88	5.70	30.42	20.70	0.34	0.01	0.83	9.40	11.77	3,482,739,200	222,573,312	15.65	6.64	524,367,616	0	0.00	152,285,328	38,788,096	13,045,212	902,696	978,972	4.90	0.04	30.76	1,193,098,752	119,514,576	258,477,920	51.12	2.31	344,426,027	37.26	42.45	29.04	65.68	3.59	0.47	1.09	5.82	9.25	9.80	13.58	0.00	45.08	51.03
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CCXI	ChemoCentryx Inc.	366.33	1,262	46.54	8	1.6	-1.29	-5.81	-26.45	0.00	44.68	70.29	57.30	56.55		0.00	0.00	70.00	88.88	120.00	3,541,227,000	311,530	462,771	541,040	-0.84	-0.37	-55.21	-133.54	0.98	1.46	0.15	8.47	8.57	3,066,938,624	-54,380,000	-56.40	47.26	64,891,000	63,917,000	16.58	-55,356,000	69,742,493	48,637,397	3,747,617	3,228,258	7.90	0.08	6.27	436,569,984	-44,427,500	-81,143,000	5.55	8.38	-12,991,000	-85.03	-83.80	-85.31	-20.02	12.14	2.52	0.00	-9.47	-24.52	-56.60	0.99	0.00	23.67	82.08
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CDMO	Avid Bioservices Inc.	374.08	1,223	19.16	4	1.7	-1.64	-1.19	40.68	310.11	4.35	22.13	18.32	11.48		0.00	0.00	21.00	21.50	22.00	1,024,962,000	285,326	831,405	543,894	-0.00	0.18	-4,790.00	106.44	1.04	1.10	2.49	1.66	1.86	1,135,615,872	7,683,000	147.81	14.05	80,812,000	21,567,000	25.26	-233,000	60,828,589	55,742,102	3,629,889	2,090,729	3.11	0.06	1.17	70,894,000	9,992,000	16,369,000	1.40	13.66	3,932,000	5.36	9.51	5.51	24.58	22.85	2.98	0.00	1.98	6.72	60.50	1.41	0.00	1.60	71.76
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CDNA	CareDx Inc.	400.42	1,094	74.27	5	1.7	-3.77	3.51	-15.28	0.00	21.75	99.83	74.78	57.06		0.00	0.00	93.00	98.00	105.00	3,187,612,000	383,355	770,982	645,083	-0.40	0.67	-184.29	107.09	0.69	1.48	2.21	3.75	3.95	3,511,746,048	-15,522,000	-226.24	18.27	192,194,000	18,173,000	6.55	-18,714,000	51,822,662	51,200,790	5,159,907	4,586,070	5.16	0.11	4.34	224,703,008	29,112,000	33,431,000	5.62	13.22	80,136,000	-11.72	-8.08	-9.74	41.70	14.30	3.11	0.00	-5.41	-9.94	63.70	4.14	0.00	1.22	1.00
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CDTX	Cidara Therapeutics Inc.	322.07	1,527	2.14	6	1.7	-1.84	-6.96	-10.08	-22.22	1.82	4.45	2.46	2.81		0.00	0.00	2.23	3.18	5.00	110,018,800	647,170	1,187,197	523,533	-1.80	-1.53	-1.19	-1.41	0.08	0.67	-0.06	1.22	1.48	82,549,232	-71,563,000	-1.15	6.84	12,067,000	7,962,000	74.31	-74,873,000	48,043,143	35,235,802	1,622,546	1,598,364	2.50	0.04	0.75	35,912,000	-35,421,376	-54,411,000	0.24	8.95	-55,950,000	-595.42	-162.18	-173.61	100.00	23.63	3.19	0.00	-69.41	-297.06	105.50	0.29	0.00	18.75	54.76
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CELC	Celcuity Inc.	217.34	2,365	25.88	2	2.0	-2.52	19.82	76.54	0.00	4.13	28.10	16.18	9.86		0.00	0.00	19.00	21.50	24.00	174,836,300	92,603	477,460	126,573	-0.92	-1.07	-28.04	-20.19	-1.76	0.77	2.00	10.00	10.27	211,170,896	-9,170,573	-23.03	0.00	0	262,488	2.24	-9,474,175	12,287,896	6,750,312	10,008	18,073	0.22	0.00	1.13	11,659,920	-3,661,379	-7,145,689	1.14	22.78	0	0.00	0.00	0.00	0.00	49.33	4.59	0.00	-35.94	-61.12	0.00	0.00	0.00	42.82	15.79
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CFRX	ContraFect Corporation	160.19	2,911	4.11	6	2.0	2.24	-1.91	-22.16	0.00	3.89	8.00	5.23	5.43		0.00	0.00	5.09	6.50	7.96	180,433,300	578,894	1,308,168	485,231	-1.24	-0.99	-3.32	-4.23	0.17	1.13	-0.39	7.01	7.80	74,034,040	-34,071,400	-2.17	0.00	0	3,679,305	20.00	-28,155,672	39,332,721	25,083,321	3,320,534	2,420,521	2.34	0.13	1.53	42,490,288	0	-33,309,668	0.45	9.05	-22,613,968	0.00	0.00	0.00	0.00	25.16	3.01	0.00	-49.70	-199.94	0.00	0.00	0.00	7.91	46.39
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CHRS	Coherus BioSciences Inc.	793.81	183	14.39	8	2.0	1.05	3.15	-20.01	0.00	13.53	22.22	15.83	17.61		0.00	0.00	18.00	27.63	35.00	1,057,692,000	1,367,677	1,182,820	1,060,675	1.61	0.83	8.93	16.81	-0.12	1.07	0.08	4.79	5.27	891,417,536	159,207,008	5.60	1.87	475,824,000	417,104,000	148.45	132,244,000	72,793,660	59,942,667	13,579,161	13,080,966	9.31	0.23	7.43	541,158,016	83,035,624	154,144,992	3.88	3.71	295,398,000	32.85	33.46	27.79	62.08	12.94	2.26	-75.50	15.63	68.49	-10.80	6.66	0.00	1.70	1.25
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CKPT	Checkpoint Therapeutics Inc.	175.28	2,743	2.85	4	1.7	-4.04	-3.39	-23.59	0.00	1.44	5.38	3.34	2.76		0.00	0.00	2.00	4.85	8.00	237,671,000	653,160	1,496,077	1,087,324	-0.41	-0.62	-6.90	-4.76	-0.14	1.33	1.08	5.65	5.90	181,104,448	0	0.00	169.42	1,069,000	0	0.00	-23,081,000	68,212,354	59,957,784	2,590,659	2,372,815	1.54	0.04	0.54	40,772,000	-13,557,625	-16,551,000	0.51	5.59	-15,283,000	-2,170.35	0.00	0.00	0.00	33.21	4.12	0.00	-41.69	-85.13	8.00	0.02	0.00	11.45	18.98
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLBS	Caladrius Biosciences Inc.	76.78	3,637	1.53	2	2.3	-1.29	-13.07	-38.80	0.00	1.25	4.89	2.00	1.89		0.00	0.00	3.18	3.18	3.18	112,194,700	1,417,974	5,213,024	2,395,658	-0.53	-0.32	-2.90	-5.50	0.07	1.33	0.16	9.86	10.08	70,526,256	-19,082,000	-3.70	0.00	0	624,000	1.94	-8,150,000	59,505,261	46,054,692	1,790,815	1,452,405	0.25	0.03	0.58	34,573,000	-13,086,625	-8,823,000	1.68	0.91	0	0.00	0.00	0.00	0.00	77.44	4.16	0.00	-37.89	-30.84	0.00	0.00	0.00	4.67	24.10
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLDX	Celldex Therapeutics Inc.	648.97	359	23.55	3	2.0	-0.04	13.71	31.34	0.00	1.87	30.17	24.53	17.71		0.00	0.00	32.00	34.33	36.00	939,717,800	310,327	728,317	696,395	-2.02	-1.69	-11.68	-13.94	0.72	-1.08	2.37	13.81	13.93	691,276,992	-45,643,000	-15.15	93.19	7,418,000	3,481,000	1.66	-59,780,000	39,614,638	28,901,255	3,556,174	2,874,990	3.71	0.09	4.91	194,422,000	-22,616,500	-40,404,000	5.29	4.46	-35,116,000	-668.27	0.00	0.00	0.00	78.25	5.59	0.00	-17.27	-39.41	326.70	0.25	0.00	5.25	94.74
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLLS	Cellectis S.A.	343.22	1,405	19.40	10	1.5	0.52	-2.61	-38.65	0.00	11.67	34.71	21.67	21.48		0.00	0.00	11.00	34.60	50.00	811,744,600	249,602	413,617	304,749	-1.91	-2.96	-10.16	-6.73	-0.18	1.63	0.91	5.23	6.06	739,294,336	-82,096,000	-9.01	8.97	82,456,000	106,679,000	34.54	-81,074,000	42,489,133	28,021,022	1,109,168	397,982	2.40	0.00	5.91	252,839,008	-102,892,128	-80,262,000	6.44	3.01	46,181,000	-103.37	-99.56	-98.32	56.01	26.88	4.09	0.00	-11.37	-29.35	150.70	1.94	0.00	0.00	36.48
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLRB	Cellectar Biosciences Inc.	106.62	3,425	1.42	6	1.6	1.43	-4.05	-26.80	0.00	1.01	2.98	1.88	1.60		0.00	0.00	1.00	1.90	3.00	84,341,790	427,212	1,702,966	1,438,912	-0.76	-0.48	-1.86	-3.08	0.05	0.65	0.35	16.04	16.26	38,038,132	-15,148,896	-2.51	0.00	0	421,644	0.77	-15,094,172	50,504,064	40,701,225	2,150,579	2,306,970	1.04	0.04	1.13	57,165,376	-8,233,984	-13,932,743	0.77	1.86	0	0.00	0.00	0.00	0.00	28.33	3.95	0.00	-26.95	-47.28	0.00	0.00	0.00	9.96	45.71
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLSN	Celsion Corporation	92.60	3,537	1.06	2	2.0	-10.92	-21.48	-39.08	0.00	0.43	6.50	1.87	1.21		0.00	0.00	1.27	1.43	1.59	129,020,199	4,254,562	16,794,447	7,644,048	-0.67	-0.26	-1.58	-5.19	0.03	0.95	0.76	2.54	2.79	90,296,144	-17,744,888	-5.09	180.59	500,000	6,194,878	33.29	-21,483,560	86,557,736	64,799,383	3,588,559	2,076,574	0.14	0.05	0.23	17,164,176	-9,996,779	-15,618,676	0.46	2.32	-10,844,819	-3,697.28	0.00	0.00	100.00	63.92	5.97	0.00	-30.48	-129.54	0.00	0.02	0.00	0.54	21.55
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLVS	Clovis Oncology Inc.	62.78	3,750	5.98	6	3.3	-1.97	-4.01	-6.27	0.00	4.08	11.10	6.72	5.93		0.00	0.00	3.00	7.13	13.00	673,171,000	3,297,219	14,343,537	7,575,947	-4.38	-1.66	-1.37	-3.75	0.02	1.15	0.16	1.46	1.68	1,057,921,728	-293,990,016	-3.60	6.43	164,522,000	646,931,008	0.00	-369,212,000	104,529,652	101,313,275	34,492,178	33,023,032	4.33	0.34	2.30	240,228,992	-162,250,000	-252,728,000	-1.53	-3.91	128,394,000	-183.68	-178.69	-224.42	78.04	47.85	4.20	0.00	-29.62	0.00	10.20	1.95	0.00	1.81	54.84
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLXT	Calyxt Inc.	427.54	958	5.58	4	2.0	-0.54	-6.53	-27.72	42.03	3.16	12.43	8.25	5.88		0.00	0.00	7.50	10.63	16.00	246,715,100	260,553	242,281	198,705	-1.32	-0.87	-4.22	-6.41	0.12	1.63	0.84	4.88	5.70	210,723,856	-41,278,000	-5.11	8.84	23,851,000	19,758,000	53.58	-44,836,000	37,155,887	12,920,960	509,867	388,953	2.22	0.04	0.78	28,997,000	-28,749,750	-43,672,000	1.00	5.61	-11,276,000	-180.90	-173.07	-187.98	-47.28	33.44	4.72	0.00	-35.62	-90.23	270.10	0.70	0.00	65.11	23.56
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CMRX	Chimerix Inc.	542.48	602	8.18	5	1.8	-1.56	-3.20	-12.42	0.00	1.37	11.57	9.58	5.38		0.00	0.00	10.00	15.00	21.00	764,258,700	348,956	732,921	720,532	-0.70	-0.43	-11.69	-19.65	0.30	1.33	1.93	9.31	9.57	647,953,472	-44,114,000	-14.69	120.62	5,372,000	2,926,000	3.99	-43,522,000	85,679,225	74,231,624	1,029,258	794,294	1.55	0.01	0.92	78,962,000	-20,795,500	-36,038,000	1.17	7.00	-30,860,000	-828.67	0.00	0.00	-217.98	67.43	4.42	0.00	-27.26	-47.48	-83.40	0.09	0.00	13.42	42.65
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CNCE	Concert Pharmaceuticals Inc.	198.38	2,522	4.41	6	1.8	-4.55	-3.50	-58.04	0.00	4.44	13.50	6.06	9.53		0.00	0.00	4.77	7.00	11.00	157,329,800	312,647	414,896	261,328	-2.40	-2.75	-1.84	-1.68	-0.12	0.97	-0.87	13.28	14.02	35,294,968	-71,042,000	-0.50	4.47	7,902,000	15,996,000	12.20	-74,766,000	32,173,778	24,876,239	779,525	698,720	2.14	0.03	4.13	131,937,000	-46,394,376	-69,037,000	4.12	1.07	-53,722,000	-919.35	0.00	0.00	100.00	28.14	3.13	0.00	-30.60	-64.28	-46.20	0.25	0.00	10.16	74.89
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CNST	Constellation Pharmaceuticals Inc.	138.60	3,110	22.29	8	2.0	-4.29	-0.93	-35.39	0.00	17.00	50.90	28.09	26.37		0.00	0.00	23.87	24.00	47.75	1,158,129,000	395,066	438,367	553,211	-2.82	-3.72	-7.92	-6.26	-0.25	0.67	-0.15	13.80	14.03	687,307,200	-124,203,000	-5.53	0.00	0	4,226,000	1.03	-126,348,000	47,856,552	32,528,577	6,581,214	6,106,271	15.83	0.20	8.81	421,448,000	-62,729,124	-111,424,000	8.60	2.59	0	0.00	0.00	0.00	0.00	34.24	3.51	0.00	-18.56	-33.77	0.00	0.00	0.00	1.67	1.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CPRX	Catalyst Pharmaceuticals Inc.	1,179.57	37	4.44	5	2.0	-0.67	2.54	20.98	0.00	2.88	5.19	4.22	3.78		0.00	0.00	5.50	7.50	9.00	454,753,400	1,156,810	1,655,050	1,761,876	0.71	0.46	6.30	9.72	0.14	1.21	0.23	6.45	7.00	322,809,984	41,395,240	7.80	2.71	119,072,800	28,772	0.02	74,983,000	103,824,973	86,586,913	12,367,735	8,399,684	6.63	0.13	1.35	140,278,176	28,964,432	45,034,864	1.63	2.72	87,122,133	34.69	34.77	62.97	73.17	21.58	2.58	56.40	16.94	58.30	3.00	1.15	0.00	6.97	66.09
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRBP	Corbus Pharmaceuticals Holdings Inc.	54.12	3,809	1.72	4	2.8	-2.27	-6.52	-27.12	0.00	0.91	9.78	2.28	3.10		0.00	0.00	1.79	2.23	3.00	243,626,300	2,944,980	11,736,065	7,722,780	-1.42	-0.47	-1.21	-3.74	0.02	2.26	-0.08	2.76	2.89	158,960,384	-121,686,376	-1.31	40.37	3,937,230	26,836,392	59.27	-111,269,376	125,033,006	123,758,920	10,843,785	13,576,196	1.76	0.09	0.68	85,433,440	-67,091,916	-99,685,704	0.46	3.76	-94,329,983	-3,119.20	-220.88	-207.87	-154.77	75.61	4.39	0.00	-101.37	-432.68	-74.40	0.05	0.00	1.16	33.74
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRIS	Curis Inc.	0.00	4,019	11.49	5	2.0	-5.90	-0.09	3.61	0.00	0.69	13.44	10.77	5.17		0.00	0.00	15.00	17.20	19.00	1,044,101,000	2,985,219	1,985,168	3,793,240	-0.62	-0.43	-18.68	-26.74	0.62	1.05	1.41	17.02	17.14	891,504,256	-24,754,000	-36.02	82.28	10,835,000	7,662,000	5.86	-29,908,000	91,519,060	63,001,082	6,427,212	2,099,274	4.51	0.07	1.84	168,494,000	-14,962,625	-25,739,000	1.43	8.05	-12,767,000	-229.79	-228.46	-276.03	-117.83	349.49	7.78	0.00	-13.00	-61.82	-8.00	0.22	0.00	6.20	75.98
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRNX	Crinetics Pharmaceuticals Inc.	308.62	1,610	16.73	5	2.0	-3.41	-1.99	11.53	0.00	11.61	23.70	16.15	14.99		0.00	0.00	23.00	33.60	42.00	521,160,499	139,499	147,758	139,933	-2.42	-3.16	-6.90	-5.40	-0.23	1.48	0.48	16.47	16.92	397,771,904	-74,005,000	-5.38	5,602.42	71,000	4,849,000	2.87	-73,812,000	33,028,876	22,281,610	1,547,594	1,383,581	13.83	0.06	5.17	170,880,000	-35,283,624	-62,027,000	5.12	3.27	-56,927,000	-105,567.61	0.00	0.00	0.00	17.13	3.49	0.00	-29.86	-51.61	-100.00	0.00	0.00	3.85	84.24
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRSP	CRISPR Therapeutics AG	48.56	3,840	118.56	17	2.3	-4.27	2.44	-35.95	0.00	46.84	220.20	131.35	118.86		0.00	0.00	45.00	157.12	210.00	8,390,714,000	1,318,906	2,036,120	1,547,593	-5.29	-6.41	-22.41	-18.06	-1.06	1.23	1.60	18.05	18.21	7,101,239,808	-345,251,008	-20.57	9,876.55	719,000	61,429,000	3.69	-348,864,992	75,612,582	65,443,646	4,220,651	3,050,951	1.64	0.06	22.41	1,690,333,056	-112,908,872	-238,366,000	22.52	5.27	-266,227,000	-49,295.55	-294.24	-273.10	-201.61	18.15	3.08	0.00	-15.31	-26.80	-99.50	0.01	0.00	12.98	64.47
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRTX	Cortexyme Inc.	108.48	3,400	38.70	8	2.7	0.10	15.21	21.85	0.00	26.66	58.99	37.01	41.66		0.00	0.00	14.00	60.48	66.63	993,837,900	277,046	333,835	204,602	0.33	-4.06	116.01	-8.27	2.14	0.58	0.36	7.87	8.11	859,281,792	-78,561,000	-10.94	0.00	0	446,000	0.26	-76,849,000	29,497,999	17,775,306	3,222,931	2,717,714	8.14	0.21	4.53	133,820,000	-24,542,124	-50,818,000	5.83	6.64	0	0.00	0.00	0.00	0.00	35.26	3.47	0.00	-31.42	-53.42	0.00	0.00	0.00	34.04	61.40
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRVS	Corvus Pharmaceuticals Inc.	214.92	2,387	2.71	3	2.3	-2.52	-6.55	-30.33	0.00	2.12	6.88	3.33	3.83		0.00	0.00	3.02	4.00	6.50	117,610,300	239,479	1,094,137	1,253,448	-0.20	-1.27	-13.35	-2.23	-0.03	0.77	0.57	3.65	3.73	63,019,168	-43,128,000	-1.46	0.00	0	2,310,000	3.20	-5,995,000	38,309,551	23,558,841	1,453,320	1,273,424	2.15	0.06	1.16	44,259,000	-19,038,000	-34,778,000	2.54	1.07	0	0.00	0.00	0.00	0.00	80.98	4.09	0.00	-32.33	-8.37	0.00	0.00	0.00	3.65	47.65
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CTIC	CTI BioPharma Corp.	339.41	1,430	2.46	4	2.0	1.24	-4.65	-24.77	0.00	0.86	4.13	3.06	2.61		0.00	0.00	2.45	4.00	4.14	213,957,700	850,309	1,116,243	1,701,114	-0.74	-0.60	-3.34	-4.30	0.18	0.23	1.24	3.08	3.19	152,837,424	-43,037,000	-3.55	83.67	2,289,000	7,448,000	18.61	-52,451,000	93,087,252	56,913,627	401,319	377,635	0.79	0.01	0.68	52,451,000	-26,289,624	-42,205,000	0.53	4.67	3,345,000	-1,612.63	-166.26	-177.54	100.00	104.09	3.71	0.00	-52.11	-180.99	0.00	0.04	0.00	0.21	50.69
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CTMX	CytomX Therapeutics Inc.	453.42	865	7.51	8	2.1	-1.83	-2.72	13.79	0.00	6.25	15.44	8.10	7.49		0.00	0.00	8.50	13.19	18.00	493,656,800	938,174	919,552	651,413	-0.71	-1.87	-10.53	-4.13	-0.06	0.93	0.08	3.14	3.21	208,886,224	-46,032,000	-4.54	2.08	100,362,000	24,870,000	49.94	-32,885,000	64,784,355	49,464,799	3,922,070	3,325,250	5.31	0.06	4.88	316,119,008	-1,083,125	5,259,000	1.03	7.28	100,362,000	-48.43	-45.87	-32.77	100.00	36.00	3.00	0.00	-8.68	-65.17	97.80	2.18	0.00	2.06	74.58
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CUE	Cue Biopharma Inc.	443.26	901	12.84	6	1.3	-0.85	4.56	-6.41	0.00	10.75	31.69	13.52	15.27		0.00	0.00	27.00	30.00	33.00	355,436,100	246,911	311,166	286,064	-1.56	-1.66	-8.23	-7.80	-1.30	1.26	-0.21	5.29	5.37	302,079,424	-43,985,128	-6.87	95.77	3,154,325	7,146,214	9.06	-44,784,920	30,457,250	22,002,317	3,136,457	2,778,520	8.72	0.11	2.79	84,868,680	-13,576,423	-32,494,034	2.60	4.94	-30,391,380	-1,427.96	0.00	0.00	0.00	16.46	3.44	0.00	-32.90	-67.10	-54.70	0.11	0.00	10.69	65.53
HEALTH CARE	Biotechnology	Biotechnology	AMEX	CVM	Cel-Sci Corporation	71.17	3,681	17.47	1	2.0	6.07	8.31	23.12	0.00	10.37	40.91	18.64	14.88		0.00	0.00	19.00	19.00	19.00	666,301,300	868,783	815,432	740,489	-0.88	-0.64	-19.97	-26.23	0.74	-0.33	0.90	2.99	3.23	645,571,392	-28,651,896	-22.53	1,233.99	523,158	13,694,647	47.49	-32,768,260	40,529,278	38,734,642	9,805,780	7,575,831	13.84	0.25	0.54	21,860,482	-8,601,347	-15,002,384	0.73	24.10	-17,281,626	-5,898.75	0.00	0.00	0.00	72.30	4.27	0.00	-48.75	-183.04	-62.70	0.01	0.00	4.12	31.48
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CWBR	CohBar Inc.	31.31	3,947	1.13	5	2.0	-0.88	-17.52	-31.52	0.00	0.85	4.25	1.53	1.34		0.00	0.00	1.11	2.04	1.00	78,830,240	428,643	606,575	593,966	-0.33	-0.43	-3.39	-2.65	-0.12	1.32	0.23	6.84	6.98	55,682,984	-13,042,851	-4.27	0.00	0	698,185	3.78	-16,264,961	61,788,325	48,272,129	2,671,875	2,759,829	5.12	0.06	0.34	21,014,840	-5,277,003	-9,778,473	0.30	3.74	0	0.00	0.00	0.00	0.00	32.54	4.37	0.00	-46.56	-122.18	0.00	0.00	0.00	23.45	13.35
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CYAD	Celyad Oncology SA	379.50	1,195	6.81	2	2.0	-2.30	-2.16	-19.69	0.00	6.57	13.01	7.50	8.75		0.00	0.00	18.01	19.01	20.01	0	29,129	16,726	13,086	-1.48	-4.12	-4.60	-1.69	-0.03	0.45	-0.17	1.53	1.67	85,413,936	-25,599,000	-3.34	17,082.79	5,000	3,638,000	11.74	-17,204,000	14,705,156	11,782,040	209,905	210,938	16.66	0.00	1.21	17,234,000	-11,105,625	-27,665,000	2.22	3.06	5,000	-524,800.00	0.00	0.00	100.00	11.88	2.71	0.00	-21.04	-44.91	-100.00	0.00	0.00	0.00	7.47
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CYCC	Cyclacel Pharmaceuticals Inc.	151.54	2,994	6.52	3	1.7	-4.40	-11.89	-11.41	0.00	3.12	19.25	7.66	5.46		0.00	0.00	6.79	7.64	18.00	59,599,890	99,140	774,006	430,394	-3.42	-2.46	-1.91	-3.01	0.07	1.14	0.63	13.97	14.27	20,220,010	-10,616,000	-1.91	0.00	0	1,057,000	3.18	-12,421,000	8,054,039	5,744,153	967,883	1,025,815	1.54	0.14	4.70	33,406,000	-6,158,500	-7,934,000	5.32	1.22	-4,759,000	-6,235.33	0.00	0.00	0.00	52.33	4.01	0.00	-25.51	-37.57	0.00	0.00	0.00	1.87	40.35
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CYCN	Cyclerion Therapeutics Inc.	70.64	3,690	2.58	1	3.0	3.20	-9.47	-22.52	0.00	2.18	8.96	3.75	4.22		0.00	0.00	4.00	4.00	4.00	104,888,500	473,467	809,643	507,404	-2.56	-1.00	-1.01	-2.85	0.02	1.88	0.41	3.22	3.45	88,395,904	-76,237,000	-1.16	38.50	2,296,000	45,735,000	76.87	-77,802,000	34,054,704	22,680,433	626,114	688,746	2.17	0.02	1.60	54,395,000	-35,801,752	-72,490,000	1.75	1.48	2,296,000	-3,420.47	0.00	0.00	100.00	52.85	4.92	0.00	-32.52	-98.97	-91.00	0.08	0.00	15.12	67.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CYTK	Cytokinetics Incorporated	261.80	1,968	24.70	11	2.0	-0.68	2.24	22.95	0.00	13.76	30.14	22.43	21.18		0.00	0.00	21.00	30.36	50.00	1,697,409,000	573,796	930,795	1,188,113	-1.97	-3.15	-12.52	-7.67	-0.21	1.02	1.02	15.10	15.20	1,392,909,568	-92,112,000	-15.12	24.95	55,828,000	138,938,000	122.54	-127,290,000	71,536,632	70,636,980	9,730,774	9,198,071	8.19	0.16	6.53	464,060,000	-69,001,872	8,943,000	1.60	15.47	-41,123,000	-168.27	-164.99	-228.00	-73.66	42.40	3.26	0.00	-14.26	-248.50	29.00	0.87	0.00	5.54	1.03
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DBVT	DBV Technologies S.A.	91.04	3,548	6.04	6	2.2	-3.36	5.23	-6.79	0.00	1.35	7.38	5.60	3.56		0.00	0.00	2.00	9.67	17.00	0	67,607	158,906	1,019,782	-1.48	-2.44	-4.09	-2.56	-0.06	1.37	0.81	3.87	3.93	504,455,072	-117,799,000	-4.28	44.74	11,276,000	15,471,000	7.53	-159,555,008	54,927,187	62,430,277	1,928,744	1,388,411	14.03	0.00	1.79	196,352,000	-72,520,376	-165,607,008	1.87	3.22	11,276,000	-1,199.81	0.00	0.00	100.00	51.20	3.86	0.00	-31.09	-80.04	32.60	0.10	0.00	0.06	31.10
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DCPH	Deciphera Pharmaceuticals Inc.	430.16	946	47.00	11	1.7	-0.49	7.28	-0.51	0.00	39.42	68.40	44.79	51.33		0.00	0.00	70.00	75.73	84.00	2,522,864,000	411,140	434,253	385,076	-4.78	-2.70	-9.84	-16.23	0.23	1.27	0.28	8.08	8.34	2,003,883,520	-268,884,992	-7.45	47.61	42,087,000	31,221,000	5.74	-266,488,992	57,625,943	36,225,397	3,437,214	2,711,373	7.69	0.08	9.58	551,929,984	-144,392,752	-239,683,008	9.44	4.98	-157,108,000	-644.36	0.00	0.00	-58.43	16.12	2.68	0.00	-26.80	-48.89	-71.60	0.76	0.00	28.94	76.96
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DFFN	Diffusion Pharmaceuticals Inc.	48.68	3,838	0.71	1	3.0	2.90	-15.48	-38.79	0.00	0.40	1.85	1.05	0.96		0.00	0.00	2.00	2.00	2.00	93,751,660	2,957,435	8,651,412	3,669,239	-0.30	-0.18	-2.37	-4.68	0.06	0.80	0.92	7.60	7.71	67,538,624	-15,871,776	-4.26	0.00	0	149,162	0.60	-16,135,684	101,903,979	101,715,457	2,229,367	517,864	0.17	0.02	0.18	18,515,596	-8,221,044	-13,552,629	0.39	1.83	0	0.00	0.00	0.00	0.00	36.88	4.99	0.00	-38.52	-63.12	0.00	0.00	0.00	0.13	6.56
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DMAC	DiaMedica Therapeutics Inc.	130.56	3,184	9.48	7	1.7	-3.66	-4.34	7.73	0.00	3.00	10.88	9.47	6.82		0.00	0.00	8.00	22.86	12.10	182,504,300	139,313	127,937	126,396	-0.78	-1.48	-12.09	-6.65	-0.14	0.80	1.67	13.73	13.77	151,735,536	-12,678,000	-11.97	0.00	0	118,000	0.45	-12,292,000	18,776,157	16,409,235	172,490	116,640	1.52	0.01	1.47	27,507,000	-4,870,875	-9,185,000	1.39	6.83	0	0.00	0.00	0.00	0.00	24.79	3.58	0.00	-42.73	-73.10	0.00	0.00	0.00	7.90	34.86
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DMTK	DermTech Inc.	281.68	1,813	43.46	4	1.6	6.00	-10.58	1.83	0.00	9.64	84.49	56.85	26.80		0.00	0.00	50.00	64.25	79.00	1,321,323,000	1,168,413	1,599,678	695,473	-3.34	-1.89	-13.00	-25.71	0.30	0.85	1.73	12.03	12.33	1,334,083,456	-33,803,000	-39.47	226.69	5,885,000	335,000	0.53	-35,249,000	28,755,668	20,895,306	2,517,958	892,249	1.37	0.11	2.22	63,777,000	-19,544,624	-28,684,000	1.58	27.52	-96,000	-582.65	0.00	0.00	-1.63	26.49	4.47	0.00	-48.71	-92.79	33.50	0.35	0.00	16.47	47.62
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DNLI	Denali Therapeutics Inc.	251.77	2,040	54.01	9	2.2	-3.62	3.35	-28.18	0.00	19.33	93.94	61.08	52.37		0.00	0.00	18.00	81.00	106.00	6,684,371,000	297,040	569,892	649,091	0.16	-2.00	337.33	-26.13	-0.81	1.14	1.64	20.58	20.86	4,921,796,096	71,249,000	69.08	14.66	335,659,008	68,865,000	5.99	71,136,000	120,984,085	79,762,388	6,668,750	6,974,175	9.76	0.09	12.15	1,469,697,024	109,032,752	416,152,000	9.55	5.66	123,044,000	18.69	21.23	21.19	36.66	35.58	3.36	0.00	3.63	9.21	6,681.10	3.08	0.00	17.37	77.45
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DRNA	Dicerna Pharmaceuticals Inc.	574.58	526	28.96	8	1.7	1.51	11.00	25.75	0.00	16.50	29.90	26.70	22.94		0.00	0.00	34.00	37.25	44.00	1,838,570,000	761,984	806,024	676,984	-1.52	-1.41	-19.05	-19.74	2.63	1.00	0.77	3.40	3.48	1,474,552,064	-110,991,000	-13.29	8.97	164,307,008	52,183,000	37.88	-112,747,000	76,320,893	63,515,774	5,325,524	4,967,839	5.71	0.07	7.45	568,843,008	52,163,500	175,112,000	1.82	15.93	-41,077,000	-68.90	-67.55	-68.62	-25.00	16.71	3.03	0.00	-10.84	-77.77	478.50	2.22	0.00	7.21	83.29
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DTIL	Precision BioSciences Inc.	173.95	2,759	8.77	8	1.8	-1.90	1.98	-35.42	0.00	4.46	16.60	11.14	8.79		0.00	0.00	8.00	18.13	8.59	568,152,300	806,255	843,747	872,117	-2.10	-1.90	-4.19	-4.71	0.45	1.38	0.66	2.33	2.47	417,070,688	-101,051,000	-4.13	17.17	24,285,000	10,519,000	23.68	-109,006,000	57,141,526	47,000,498	6,012,796	3,387,824	7.49	0.12	1.58	89,798,000	-39,090,500	-87,386,000	0.84	10.40	24,285,000	-452.25	0.00	0.00	100.00	29.47	4.22	0.00	-35.62	-119.30	35.60	0.47	0.00	11.29	49.49
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DVAX	Dynavax Technologies Corporation	648.66	360	10.99	3	1.7	1.20	9.14	118.06	0.00	3.16	12.44	9.69	6.80		0.00	0.00	16.00	18.00	20.00	1,150,682,000	2,380,475	3,755,212	4,615,872	-0.78	0.20	-14.05	54.30	0.11	1.17	1.51	2.43	3.75	1,201,227,904	-60,743,000	-19.78	25.81	46,551,000	217,847,008	371.16	-75,240,000	113,256,101	101,552,216	18,391,195	20,355,229	5.60	0.22	1.46	165,036,000	-85,589,248	-92,251,000	0.53	20.62	6,534,000	-145.04	-130.49	-161.63	14.04	61.87	5.09	0.00	-13.35	-224.65	85.00	0.46	0.00	0.72	74.99
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DYAI	Dyadic International Inc.	283.22	1,802	5.01	2	2.0	-1.57	-3.10	-11.33	0.00	4.56	10.98	5.48	6.73		0.00	0.00	10.00	11.00	12.00	147,029,500	98,014	740,090	307,356	-0.34	0.28	-14.78	18.46	0.08	0.81	0.19	18.15	18.32	113,360,496	0	0.00	70.77	1,601,921	0	0.00	-9,325,273	27,554,157	17,995,069	653,809	749,039	4.27	0.03	1.06	29,094,496	-3,807,788	-6,574,392	1.04	4.84	176,990	-621.96	0.00	0.00	11.05	33.11	2.93	0.00	-18.44	-29.00	-20.10	0.06	0.00	30.16	22.02
HEALTH CARE	Biotechnology	Biotechnology	NYSE	EBS	Emergent Biosolutions Inc.	477.52	786	77.64	7	2.0	4.26	0.38	-29.46	0.00	64.04	137.61	95.34	99.35		0.00	0.00	86.00	119.57	150.00	5,038,449,000	491,777	763,413	720,965	5.63	5.42	13.80	14.27	4.67	0.96	0.55	2.22	3.11	4,424,455,168	604,499,968	7.32	2.85	1,555,399,936	923,000,000	63.79	305,100,000	53,300,000	47,632,611	2,619,078	2,394,625	3.56	0.07	11.66	621,299,968	391,100,000	536,000,000	27.25	2.85	857,600,000	31.79	38.87	19.62	55.14	21.03	2.74	2.86	11.86	24.07	61.80	29.51	0.00	14.70	84.51
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EDIT	Editas Medicine Inc.	115.39	3,331	34.67	7	2.8	-15.40	-12.14	-45.65	0.00	21.41	99.95	47.25	43.18		0.00	0.00	30.00	53.57	81.00	2,726,846,000	6,774,223	2,212,054	1,773,648	-1.98	-3.49	-17.52	-11.31	-0.23	1.67	0.84	7.01	7.20	2,277,188,864	-130,881,000	-17.40	25.10	90,732,000	26,135,000	6.64	-115,976,000	67,362,791	66,372,798	10,613,348	9,842,867	4.11	0.16	5.98	402,110,016	-77,357,000	-179,843,008	6.29	5.51	-67,264,000	-148.61	-144.25	-127.82	-74.14	31.97	3.94	0.00	-15.59	-35.36	-7.00	1.55	0.00	1.33	73.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EGRX	Eagle Pharmaceuticals Inc.	478.20	782	44.27	3	2.2	-0.09	6.52	-7.92	0.00	36.48	56.16	44.31	45.43		0.00	0.00	46.00	48.00	52.00	551,821,600	111,628	125,254	144,288	0.89	4.02	49.88	10.34	7.11	0.63	-0.26	4.05	4.36	484,372,320	36,492,000	13.27	2.58	187,802,000	38,217,000	20.55	11,989,000	13,030,130	10,860,774	1,402,280	1,295,122	10.66	0.17	7.81	103,155,000	50,082,624	49,497,000	14.25	3.11	142,337,000	17.55	19.43	6.38	75.79	10.91	1.75	7.73	8.11	6.57	3.40	13.93	0.00	14.63	95.38
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EIGR	Eiger BioPharmaceuticals Inc.	334.68	1,459	8.30	6	1.0	-1.19	-1.19	-21.33	0.00	6.76	13.99	9.84	10.05		0.00	0.00	10.08	15.60	22.00	301,383,300	134,773	218,407	431,809	-2.31	-1.79	-3.59	-4.69	0.16	1.21	0.39	7.75	8.29	188,445,648	-61,982,000	-3.04	0.00	0	32,514,000	34.21	-65,051,000	33,901,386	28,992,465	1,531,095	1,583,898	7.48	0.05	3.80	128,840,000	-38,458,376	-63,185,000	2.81	2.96	0	0.00	0.00	0.00	0.00	23.48	3.27	0.00	-31.23	-85.87	0.00	0.00	0.00	1.28	71.65
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ENLV	Enlivex Therapeutics Ltd.	39.23	3,906	10.97	1	0.0	-2.32	-6.40	-8.58	0.00	4.49	29.40	14.33	9.92		0.00	0.00	10.50	10.50	10.50	173,831,500	85,397	509,349	562,935	-0.74	-1.07	-14.76	-10.95	-0.34	1.03	1.17	6.61	7.23	130,301,400	-8,679,000	-15.01	0.00	0	682,000	2.39	-9,025,000	15,759,878	9,240,051	100,128	57,868	0.25	0.01	2.09	28,176,000	-4,035,375	-6,900,000	2.12	5.18	0	0.00	0.00	0.00	0.00	47.54	4.32	0.00	-21.22	-41.75	0.00	0.00	0.00	28.63	12.03
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ENTA	Enanta Pharmaceuticals Inc.	184.90	2,650	50.68	7	2.5	-2.09	3.96	8.27	0.00	40.32	58.59	50.99	47.54		0.00	0.00	35.00	68.14	107.00	1,010,408,000	103,235	145,357	160,414	-2.89	-4.79	-17.52	-10.18	-0.27	0.65	-0.02	18.14	19.35	607,377,792	-63,198,000	-9.61	5.98	101,646,000	10,196,000	2.26	-57,939,000	20,171,852	13,830,225	2,168,583	2,131,716	13.03	0.14	19.15	386,196,000	-11,112,625	-20,165,000	22.44	2.26	122,473,000	-65.73	-62.18	-57.00	100.00	7.70	1.87	0.00	-8.42	-12.40	-39.60	5.08	0.00	11.47	96.91
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ENTX	Entera Bio Ltd.	145.90	3,047	3.00	2	2.0	-9.09	-14.29	70.46	0.00	1.00	10.16	2.95	1.73		0.00	0.00	3.18	3.50	3.82	84,984,340	481,788	10,355,419	3,004,860	-0.55	-0.65	-5.49	-5.38	-0.29	0.90	0.85	2.70	2.78	74,924,248	-11,366,000	-6.59	205.27	365,000	432,000	6.48	-9,983,000	23,738,642	16,678,058	1,537,266	156,528	0.06	0.08	0.36	8,593,000	-7,519,250	-10,423,000	0.32	9.46	156,000	-3,136.16	0.00	0.00	42.74	152.30	5.12	0.00	-53.06	-107.44	116.70	0.02	0.00	29.77	7.77
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EPZM	Epizyme Inc.	344.99	1,392	8.10	9	2.1	-1.58	-3.23	-28.89	0.00	7.44	22.00	9.36	11.85		0.00	0.00	10.00	11.46	18.89	803,084,900	1,161,014	1,221,425	1,014,889	-2.30	-1.79	-3.53	-4.68	0.16	1.28	-0.92	8.69	9.33	764,382,784	-218,434,000	-3.50	48.50	15,762,000	249,920,000	135.17	-231,694,000	101,785,162	81,407,773	12,087,972	11,862,813	11.68	0.16	3.67	373,606,016	-168,391,376	-206,336,000	1.46	5.53	-100,238,000	-1,430.12	0.00	0.00	-297.94	23.48	2.77	0.00	-31.37	-89.80	95.00	0.16	0.00	4.17	99.11
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ERYP	Erytech Pharma S.A.	145.74	3,049	6.91	2	1.7	-3.49	1.77	-41.04	0.00	5.00	13.95	8.06	7.96		0.00	0.00	13.00	17.76	7.16	0	1,274	16,065	10,974	-4.78	-3.38	-1.45	-2.08	0.05	0.71	0.77	1.66	1.69	126,514,040	-65,375,000	-1.94	34.03	3,718,000	27,448,000	103.43	-73,300,000	21,619,894	14,101,316	4,488	4,359	0.66	0.00	2.22	44,454,000	-27,320,250	-51,720,000	1.32	5.22	3,718,000	-1,851.32	0.00	0.00	100.00	41.11	4.12	0.00	-43.25	-130.78	-40.90	0.20	0.00	0.00	23.53
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ESPR	Esperion Therapeutics Inc.	183.05	2,671	27.02	11	2.4	-0.07	0.26	6.17	0.00	23.90	53.73	29.03	32.77		0.00	0.00	19.10	24.00	65.55	765,348,100	315,911	607,169	684,151	-5.23	-3.37	-5.17	-8.00	0.15	0.97	-0.18	3.24	3.68	810,103,424	-120,849,000	-6.70	3.56	227,547,008	362,012,000	1,985.59	-143,551,008	27,942,612	26,105,944	9,763,682	9,546,229	15.10	0.41	10.91	304,961,984	-77,038,248	-85,177,000	-3.71	-7.28	78,219,000	-53.35	-53.11	-63.09	34.38	16.41	3.15	0.00	-26.73	-260.79	881.50	8.28	0.00	0.98	1.15
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ETTX	Entasis Therapeutics Holdings Inc.	222.32	2,322	1.90	7	1.9	-4.04	-7.77	-38.71	0.00	1.58	4.25	2.64	2.52		0.00	0.00	2.00	2.86	5.00	76,486,020	191,643	291,480	440,740	-2.10	-1.43	-0.91	-1.44	0.03	0.85	-0.17	6.44	7.02	24,933,124	-54,090,000	-0.46	0.00	0	1,321,000	2.53	-50,496,000	37,310,254	16,110,941	274,780	193,165	0.90	0.01	1.43	53,247,000	-28,797,376	-45,426,000	1.43	1.33	7,000,000	0.00	0.00	0.00	0.00	20.96	3.35	0.00	-60.21	-106.93	0.00	0.00	0.00	56.58	17.38
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EVGN	Evogene Ltd.	99.04	3,484	4.37	1	2.0	2.58	-6.02	-29.97	0.00	0.94	10.24	6.00	3.84		0.00	0.00	4.77	4.77	4.77	0	800,725	1,428,724	1,199,858	-0.83	-0.58	-5.27	-7.34	0.17	1.92	1.76	5.21	5.36	152,165,888	-22,845,000	-6.66	146.31	1,040,000	2,440,000	4.29	-23,374,000	40,414,229	38,890,613	861,989	1,392,148	0.71	0.03	1.19	48,229,000	-6,909,875	-19,514,000	1.29	3.38	466,000	-2,385.96	0.00	0.00	44.81	31.11	5.47	0.00	-21.65	-44.76	202.60	0.04	0.00	10.64	23.91
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EVLO	Evelo Biosciences Inc.	133.73	3,154	11.56	5	2.5	3.68	15.14	-17.55	0.00	3.55	19.93	12.76	8.25		0.00	0.00	11.00	11.46	20.20	603,218,300	175,606	262,099	249,595	-2.37	-2.02	-4.87	-4.97	0.33	1.63	1.51	3.47	3.58	508,336,864	-89,860,000	-5.66	0.00	0	41,711,000	136.83	-93,666,000	53,334,947	27,001,350	2,936,514	2,630,810	12.57	0.09	1.29	68,857,000	-40,411,752	-73,063,000	0.64	18.01	0	0.00	0.00	0.00	0.00	24.82	4.81	0.00	-63.26	-206.58	0.00	0.00	0.00	0.45	80.60
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EXAS	Exact Sciences Corporation	325.58	1,504	130.04	16	1.6	-0.37	3.59	-12.18	0.00	70.75	159.54	133.58	115.22		0.00	0.00	154.00	170.63	226.00	21,305,740,000	760,553	1,677,622	1,761,563	-5.61	-2.57	-23.16	-48.85	0.43	0.78	1.23	3.60	3.82	21,139,111,936	-418,656,000	-50.49	14.17	1,491,390,976	1,751,143,040	62.02	-848,532,992	169,093,162	167,523,977	8,850,288	8,417,126	4.43	0.06	10.88	1,839,986,944	-148,540,624	136,482,000	17.71	7.34	1,137,067,000	-39.03	-28.07	-56.90	76.24	26.55	2.54	0.00	-8.63	-33.20	57.80	9.87	0.00	0.89	94.27
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EXEL	Exelixis Inc.	663.62	339	23.59	14	1.9	-1.50	2.03	10.65	0.00	18.18	27.80	22.72	22.35		0.00	0.00	26.00	31.36	37.00	7,079,045,000	1,717,714	1,880,503	2,095,222	0.35	1.04	67.57	23.03	-1.15	0.80	0.64	6.70	7.06	6,348,926,464	121,901,000	52.08	6.43	987,537,984	52,111,000	2.77	111,781,000	311,989,661	284,812,242	13,022,178	12,633,058	7.09	0.05	3.87	1,206,535,936	136,044,000	208,982,000	6.03	3.91	953,966,000	11.42	12.34	11.32	96.60	21.21	2.11	-59.10	3.50	6.27	12.40	3.20	0.00	1.90	84.16
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FATE	Fate Therapeutics Inc.	251.47	2,045	81.17	17	1.9	-3.83	4.08	-18.56	0.00	25.60	121.16	89.71	64.68		0.00	0.00	88.00	113.65	135.00	6,767,408,000	536,840	997,936	974,305	-2.11	-2.17	-38.56	-39.05	-12.49	1.50	1.56	5.73	5.78	6,928,550,400	-124,998,000	-55.43	220.42	31,434,000	97,298,000	25.31	-173,387,008	93,892,256	79,653,971	12,057,806	10,301,406	10.74	0.17	5.15	482,916,000	2,314,875	-39,229,000	4.38	18.52	-94,189,000	-407.47	0.00	0.00	-299.64	37.17	3.62	0.00	-17.31	-55.11	467.30	0.38	0.00	1.69	96.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FBIO	Fortress Biotech Inc.	226.67	2,278	4.12	6	2.0	-7.21	-24.27	19.42	0.00	1.89	6.10	4.10	3.41		0.00	0.00	4.50	7.64	10.25	347,637,600	1,950,460	2,168,629	1,398,128	-0.65	0.36	-6.38	15.11	0.04	1.30	1.14	5.29	5.45	468,685,504	-90,470,000	-5.18	10.28	45,599,000	89,076,000	45.22	-46,526,000	94,907,448	58,033,057	1,446,102	1,198,492	0.98	0.02	2.46	233,351,008	-55,765,000	-83,682,000	1.06	3.89	31,005,000	-206.52	-198.40	-102.03	68.00	25.70	3.97	0.00	-21.20	-76.42	23.50	0.63	0.00	28.85	34.48
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FENC	Fennec Pharmaceuticals Inc.	285.99	1,780	6.27	3	1.5	-2.49	-0.16	-19.72	0.00	4.80	10.67	7.26	7.34		0.00	0.00	11.00	13.00	15.00	160,536,200	88,977	106,444	210,646	-0.76	0.30	-8.21	20.37	0.06	1.05	0.22	12.93	13.39	132,953,920	0	0.00	782.08	170,000	0	0.00	-18,109,000	26,002,853	19,843,297	1,001,356	911,337	15.48	0.06	1.17	30,344,000	-8,915,375	-15,595,000	1.12	5.61	170,000	-10,520.59	0.00	0.00	100.00	34.47	3.03	0.00	-49.07	-88.46	0.00	0.01	0.00	16.95	56.53
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FGEN	FibroGen Inc	249.28	2,055	19.91	7	2.5	3.16	7.22	-55.38	0.00	18.12	57.21	37.79	41.52		0.00	0.00	17.83	25.00	40.57	2,921,695,000	3,882,822	1,817,170	970,129	-2.11	-2.22	-9.45	-8.36	-1.76	1.25	-0.55	4.46	4.63	1,092,611,840	-169,832,992	-6.43	6.20	176,319,008	59,600,000	13.50	-189,291,008	91,010,718	84,972,692	8,505,210	6,296,668	6.18	0.11	7.50	686,537,024	129,764,752	81,602,000	4.62	4.31	-85,474,000	-108.82	-96.32	-107.36	-48.48	42.82	2.64	0.00	-14.24	-38.76	715.10	1.96	0.00	8.03	79.98
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FIXX	Homology Medicines Inc.	343.19	1,407	6.81	10	1.6	-3.13	-6.97	-46.67	0.00	6.76	17.34	10.42	11.42		0.00	0.00	8.59	11.78	14.00	481,652,200	906,246	652,114	558,749	-2.80	-2.60	-2.43	-2.82	0.34	1.00	-0.61	9.61	9.69	167,557,968	-122,298,000	-1.37	62.01	2,702,000	15,442,000	7.88	-128,694,000	56,864,972	29,560,728	2,234,517	2,085,762	4.96	0.04	4.31	217,431,008	-54,095,376	-94,332,000	3.90	1.75	-97,690,000	-4,820.98	0.00	0.00	0.00	22.60	3.10	0.00	-28.35	-56.63	74.10	0.06	0.00	13.05	65.12
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FLXN	Flexion Therapeutics Inc.	365.65	1,269	9.41	13	1.8	-2.69	15.89	-17.60	0.00	7.80	14.39	10.55	11.62		0.00	0.00	11.14	15.00	20.38	451,812,200	568,794	910,336	634,488	-2.53	-0.60	-3.73	-13.53	0.05	1.40	0.44	3.72	4.09	461,345,920	-91,323,000	-5.05	5.39	85,552,000	231,355,008	1,372.51	-113,706,000	49,924,004	45,466,789	7,746,811	8,189,963	11.90	0.21	3.51	175,392,000	-38,827,752	-70,561,000	-0.34	-27.92	66,533,000	-108.73	-106.75	-132.91	77.77	15.11	3.10	0.00	-24.77	-6,256.74	11.20	1.90	0.00	4.89	97.69
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FOLD	Amicus Therapeutics Inc.	406.43	1,064	9.94	11	2.6	-3.78	8.16	-50.84	0.00	8.83	25.39	11.63	16.46		0.00	0.00	12.50	18.14	29.00	2,534,791,000	2,258,581	4,508,969	2,819,762	-1.07	-0.40	-9.30	-25.83	0.15	1.11	0.10	4.09	4.47	2,596,335,360	-235,008,000	-11.05	9.95	260,886,000	441,729,984	154.25	-276,852,000	260,587,610	215,695,132	33,145,540	32,063,988	8.63	0.13	1.83	483,268,992	-137,546,368	-233,290,000	1.09	9.09	229,842,000	-93.47	-90.08	-106.12	88.10	32.84	2.61	0.00	-17.55	-72.59	27.60	1.01	0.00	0.43	1.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FPRX	Five Prime Therapeutics Inc.	90.46	3,553	38.00	6	2.6	0.03	0.16	175.16	0.00	2.64	38.90	31.66	15.33		0.00	0.00	33.00	37.17	38.00	1,765,080,000	0	2,325,515	1,592,226	-2.29	-1.89	-16.60	-20.11	0.95	0.78	1.65	12.95	13.18	1,500,221,056	-73,230,000	-20.49	113.84	13,178,000	47,434,000	17.89	-84,328,000	46,572,029	26,053,057	2,973,047	2,848,578	0.76	0.07	6.27	287,259,008	-28,428,250	-64,654,000	5.78	6.57	-43,243,000	-579.95	0.00	0.00	0.00	232.09	7.17	0.00	-17.19	-40.58	0.00	0.36	0.00	2.89	1.08
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FREQ	Frequency Therapeutics Inc.	127.56	3,220	9.59	3	2.2	-2.14	-11.53	-73.21	0.00	7.33	58.37	32.83	27.72		0.00	0.00	11.14	14.00	23.00	292,817,100	1,016,468	1,667,585	565,511	-10.29	-0.43	-0.93	-23.33	0.01	1.24	0.49	8.38	8.45	196,140,032	-26,404,000	-7.43	5.30	36,984,000	45,994,000	23.89	-26,511,000	34,177,771	26,253,313	7,956,233	5,315,388	3.43	0.26	6.45	220,340,992	-40,026,752	-45,188,000	-25.04	-0.38	36,984,000	-74.49	-71.39	-71.68	100.00	77.82	4.15	0.00	-7.06	-14.74	111.30	1.15	0.00	12.36	63.37
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FWP	Forward Pharma A/S	40.76	3,899	7.09	0	0.0	1.14	-3.14	7.75	0.00	5.65	12.72	7.29	6.79		0.00	0.00	0.00	0.00	0.00	46,891,790	28,628	62,487	48,833	-0.49	-0.09	-14.53	-75.67	0.18	0.49	0.35	118.37	118.57	-20,119,144	-4,078,500	4.93	0.00	0	0	0.00	-3,630,000	95,073,864	1,426,881	2,754	2,651	0.06	0.00	9.37	75,626,000	0	0	9.36	0.76	0	0.00	0.00	0.00	0.00	20.83	2.27	0.00	-3.25	-4.67	0.00	0.00	0.00	0.00	13.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GALT	Galectin Therapeutics Inc.	92.52	3,538	2.19	1	2.0	-1.79	-16.41	0.46	0.00	1.70	3.85	2.30	2.55		0.00	0.00	3.82	3.82	3.82	122,715,700	1,323,577	2,027,992	705,583	-0.41	-0.87	-5.29	-3.01	-0.05	0.90	0.63	5.03	5.46	124,908,800	0	0.00	0.00	0	52,000	0.22	-23,602,000	57,156,030	41,312,950	4,662,465	4,671,091	18.01	0.21	0.48	27,142,000	-11,891,875	-20,601,000	0.38	5.70	0	0.00	0.00	0.00	0.00	35.74	3.24	0.00	-37.54	-67.25	0.00	0.00	0.00	29.12	17.81
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GBT	Global Blood Therapeutics Inc.	164.49	2,869	40.81	20	2.0	-1.26	0.10	-14.78	-41.42	36.49	83.69	44.00	52.41		0.00	0.00	45.00	80.70	43.93	2,488,761,000	636,782	915,309	1,050,684	-4.04	-2.25	-10.11	-18.14	0.23	0.82	-0.51	7.32	8.00	2,240,878,080	-239,632,992	-9.35	18.10	123,803,000	232,827,008	55.95	-247,552,992	62,156,860	54,962,825	11,478,074	11,858,508	13.47	0.21	9.02	560,892,032	-137,616,128	-211,862,000	6.72	6.07	121,817,000	-197.21	-193.56	-199.96	98.40	36.49	2.51	0.00	-20.08	-49.77	1,859.00	2.02	0.00	1.87	1.06
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GERN	Geron Corporation	268.31	1,913	1.47	6	1.7	-2.65	-0.68	-11.98	0.00	1.10	2.40	1.75	1.80		0.00	0.00	2.23	3.00	4.00	506,463,900	1,666,615	3,623,722	3,054,176	-0.28	-0.35	-5.27	-4.23	-0.21	1.10	0.63	6.37	6.46	304,864,768	-76,755,000	-3.97	1,205.00	253,000	29,719,000	14.09	-75,617,000	318,530,740	259,303,714	35,947,820	36,386,350	8.48	0.11	0.62	196,275,008	-39,897,624	-66,652,000	0.68	2.16	-49,799,000	-30,400.39	0.00	0.00	-94.10	24.02	3.09	0.00	-22.04	-43.70	-70.80	0.00	0.00	0.17	55.83
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GILD	Gilead Sciences Inc.	506.44	706	66.87	25	2.3	1.67	2.70	-0.16	0.00	56.56	85.79	64.84	64.78	2021-03-12	2.84	4.35	60.00	74.68	100.00	81,980,140,000	7,610,602	7,893,353	8,835,038	0.06	6.78	1,173.98	9.70	-27.62	0.51	-0.73	1.19	1.40	105,579,536,384	12,696,999,936	8.32	4.28	24,689,000,448	32,117,000,192	176.26	123,000,000	1,256,603,612	1,255,437,090	23,435,889	23,826,782	2.71	0.02	6.85	8,611,999,744	7,914,625,024	8,168,000,000	14.52	4.61	20,998,000,000	45.43	51.43	0.50	85.05	5.99	1.22	-41.80	10.78	0.44	26.20	19.64	0.00	0.09	79.43
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GLMD	Galmed Pharmaceuticals Ltd.	109.39	3,390	3.07	5	1.8	-3.46	-8.90	-16.35	0.00	2.96	6.29	3.81	3.91		0.00	0.00	2.50	3.18	5.22	85,034,470	279,099	460,893	198,623	-1.35	-1.31	-2.27	-2.57	0.73	0.63	-0.21	6.36	6.47	34,065,792	-30,171,000	-1.13	0.00	0	419,000	0.95	-28,771,000	25,083,914	16,319,344	221,459	39,442	0.48	0.01	2.03	50,886,000	-15,931,250	-26,287,000	2.07	1.48	0	0.00	0.00	0.00	0.00	22.59	3.29	0.00	-29.16	-50.47	0.00	0.00	0.00	14.14	26.22
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GLPG	Galapagos NV	160.35	2,909	79.15	7	2.8	-0.30	1.72	-29.29	0.00	74.51	233.14	83.61	124.91		0.00	0.00	75.03	93.61	117.05	0	422,085	344,860	230,833	-5.63	-4.54	-14.07	-17.49	0.73	0.80	-1.61	8.40	8.45	61,011,184	-170,674,000	-0.36	0.12	530,260,000	29,436,000	1.10	-311,000,992	65,511,581	43,103,738	1,138,046	936,943	4.57	0.00	78.91	5,161,464,832	-170,068,128	-427,336,000	40.82	1.94	6,593,000	-33.69	-32.19	-57.60	1.24	24.78	2.10	0.00	-1.89	-11.22	0.00	8.15	0.00	0.00	8.64
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GLYC	GlycoMimetics Inc.	336.60	1,442	2.61	4	2.0	2.35	-9.69	-32.03	0.00	2.37	5.19	3.33	3.59		0.00	0.00	3.00	3.26	4.77	156,540,500	544,780	924,310	633,562	-1.12	-1.40	-2.34	-1.82	-0.09	1.26	0.35	11.03	11.13	-3,937,718	-51,238,636	0.08	-0.39	10,162,935	2,818,564	2.20	-51,026,904	51,539,010	31,848,259	1,317,597	1,071,328	1.48	0.03	2.66	137,035,024	-20,618,000	-39,241,932	2.62	1.00	10,162,935	-506.84	0.00	0.00	100.00	14.94	3.18	0.00	-20.72	-36.14	0.00	0.22	0.00	2.16	78.43
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GMDA	Gamida Cell Ltd.	289.78	1,744	7.65	6	1.9	-2.17	-2.30	-14.53	0.00	3.86	15.00	9.09	6.77		0.00	0.00	8.59	14.00	19.00	464,331,200	272,248	953,043	589,365	-1.66	-1.97	-4.60	-3.97	-0.25	0.42	1.08	5.91	6.03	344,277,184	-61,943,000	-5.56	0.00	0	7,910,000	8.01	-72,704,000	59,200,153	41,100,298	1,967,580	1,330,157	2.71	0.04	2.15	127,170,000	-37,934,376	-48,627,000	1.67	4.57	0	0.00	0.00	0.00	0.00	55.89	3.54	0.00	-34.73	-108.74	0.00	0.00	0.00	27.99	53.42
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GNCA	Genocea Biosciences Inc.	88.47	3,568	2.21	5	1.4	-4.33	-16.92	-31.79	0.00	1.74	5.75	2.93	2.61		0.00	0.00	2.86	4.40	2.13	142,894,300	216,933	471,970	676,700	-1.11	-0.80	-1.99	-3.33	0.07	1.21	0.60	3.19	3.29	86,464,168	-46,451,000	-1.86	63.62	1,359,000	23,874,000	265.80	-43,714,000	53,518,483	26,445,623	1,669,056	1,687,245	3.42	0.04	1.49	79,769,000	-26,424,624	-41,651,000	0.17	13.08	1,359,000	-3,457.62	0.00	0.00	100.00	30.62	4.73	0.00	-38.87	-256.96	0.00	0.03	0.00	7.78	62.54
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GNPX	Genprex Inc.	157.98	2,934	3.96	3	2.0	-0.75	-11.21	5.60	0.00	1.95	7.72	5.19	4.03		0.00	0.00	5.00	6.67	8.00	213,218,200	514,256	1,346,776	1,274,168	-0.51	0.60	-7.84	7.43	0.04	1.46	1.09	60.61	68.15	165,694,688	-17,938,804	-9.24	0.00	0	0	0.83	-17,942,770	43,276,764	33,725,582	3,491,165	3,269,400	3.08	0.09	0.63	27,319,684	-11,775,806	-13,935,086	0.72	5.52	0	0.00	0.00	0.00	0.00	51.16	4.32	0.00	-64.33	-105.73	0.00	0.00	0.00	17.46	18.67
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GOSS	Gossamer Bio Inc.	186.47	2,635	8.49	8	1.9	-4.07	-2.86	-16.44	0.00	7.92	16.79	9.73	10.96		0.00	0.00	9.23	12.00	21.25	692,589,100	446,474	696,411	694,028	-3.55	-3.02	-2.39	-2.89	0.16	1.49	-0.14	13.27	13.51	302,104,768	-209,172,992	-1.44	0.00	0	183,732,000	57.29	-243,360,000	75,527,707	48,435,447	8,372,728	7,652,456	10.71	0.14	7.10	512,628,000	-119,235,000	-176,360,000	4.55	1.87	0	0.00	0.00	0.00	0.00	25.65	3.00	0.00	-27.25	-72.30	0.00	0.00	0.00	11.04	82.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GRFS	Grifols S.A.	433.70	933	17.98	2	1.7	-1.59	-0.11	-6.98	0.00	14.81	21.88	16.67	17.82	2020-10-30	0.42	2.32	19.51	27.32	35.12	0	933,335	961,241	1,092,714	0.54	1.57	33.36	11.64	-0.98	0.49	-0.28	0.82	2.37	32,945,584,128	1,191,277,952	27.66	6.17	5,340,038,144	6,911,398,912	102.85	618,545,984	261,425,110	1,105,413,314	3,757,724	3,798,070	3.54	0.00	0.43	590,670,016	715,559,488	1,110,336,000	3.73	4.82	2,255,165,000	18.27	22.31	11.58	42.23	7.03	1.64	-34.20	3.96	10.45	-3.80	3.90	0.00	0.00	44.61
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GRTS	Gritstone Oncology Inc.	0.00	4,019	8.64	3	2.0	-2.37	-5.06	-66.18	0.00	2.54	35.20	12.76	6.86		0.00	0.00	11.14	17.00	25.33	537,977,700	746,077	1,004,742	1,456,123	-2.79	-2.77	-3.10	-3.29	5.08	1.71	0.71	6.34	6.50	299,500,192	-99,373,000	-3.01	74.19	4,037,000	25,099,000	15.05	-105,314,000	48,951,561	30,330,877	3,076,419	2,841,430	4.72	0.09	3.49	171,058,000	-52,737,624	-89,102,000	3.51	2.46	-84,606,000	-2,626.13	0.00	0.00	0.00	248.46	4.72	0.00	-32.64	-69.96	52.60	0.11	0.00	8.29	73.17
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GTHX	G1 Therapeutics Inc.	269.23	1,906	23.51	6	1.7	-6.37	-8.06	9.86	0.00	10.81	37.07	24.49	18.52		0.00	0.00	24.83	41.00	59.00	922,267,200	871,290	1,592,695	1,147,313	-2.62	-3.48	-8.97	-7.10	-0.27	1.32	1.16	8.85	9.23	894,341,312	-95,894,000	-9.33	19.75	45,285,000	28,746,000	16.21	-99,254,000	41,959,379	35,037,340	7,436,433	6,331,722	5.46	0.27	4.94	207,306,000	-45,364,752	-83,742,000	4.65	5.05	45,285,000	-213.04	-211.76	-219.18	100.00	27.36	3.57	0.00	-23.49	-45.86	0.00	1.20	0.00	10.09	72.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HALO	Halozyme Therapeutics Inc.	443.45	900	46.41	10	2.3	0.46	8.51	-2.30	137.35	18.58	56.40	44.93	36.74		0.00	0.00	17.00	48.10	64.00	5,601,795,000	719,542	1,462,126	1,445,616	0.90	2.66	51.64	16.15	0.27	0.89	2.26	1.11	1.32	5,817,210,368	145,839,008	39.89	21.74	267,594,000	402,096,000	266.21	129,085,000	143,301,550	133,902,996	8,280,551	14,431,992	4.10	0.07	2.72	368,012,992	2,754,125	55,454,000	1.12	41.47	189,991,000	53.91	54.50	48.24	71.00	13.92	2.07	0.00	15.74	106.33	126.80	1.97	0.00	1.22	98.41
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HARP	Harpoon Therapeutics Inc.	544.98	596	20.00	9	1.4	-1.28	-11.78	-9.95	0.00	10.55	25.24	19.95	16.83		0.00	0.00	25.00	31.22	35.00	640,113,100	70,112	249,761	258,678	-1.99	-2.04	-10.03	-11.11	-4.35	0.91	0.95	2.63	2.71	622,193,600	-49,249,000	-12.63	35.67	17,444,000	13,515,000	25.10	-49,908,000	32,410,789	17,414,895	792,522	678,029	3.01	0.03	3.89	126,030,000	-1,182,875	-8,616,000	2.11	9.49	-35,121,000	-294.26	-282.33	-286.10	-201.34	30.40	3.75	0.00	-18.43	-67.42	235.40	0.70	0.00	8.65	60.03
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HGEN	Humanigen Inc.	249.08	2,057	14.73	6	1.9	-5.33	-14.61	-21.52	0.00	3.85	33.95	17.85	15.99		0.00	0.00	25.00	34.33	40.00	748,218,300	991,737	3,248,927	1,260,494	-2.42	3.77	-6.08	4.13	0.02	0.91	1.31	3.32	3.34	754,821,760	0	0.00	2,419.30	312,000	0	0.00	-89,535,000	58,482,364	33,975,207	7,960,839	2,322,152	1.37	0.52	1.27	67,737,000	-41,593,752	-69,853,000	0.88	16.70	312,000	-28,268.59	0.00	0.00	100.00	126.07	7.33	0.00	-160.19	-573.45	0.00	0.01	0.00	36.64	25.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HOOK	HOOKIPA Pharma Inc.	620.58	425	12.54	8	1.6	-0.87	-8.53	2.70	0.00	7.28	15.52	12.58	11.12		0.00	0.00	16.00	22.00	28.00	412,880,300	100,935	201,064	112,138	-1.69	-2.55	-7.41	-5.38	-0.15	1.19	0.99	7.73	8.11	276,435,904	-49,135,000	-5.63	14.12	19,584,000	10,767,000	6.90	-44,082,000	25,969,612	14,647,718	1,290,454	1,297,854	6.65	0.07	4.79	142,743,008	-29,821,376	-39,339,000	5.25	2.39	-35,203,000	-272.08	-250.89	-225.09	-179.75	18.75	3.05	0.00	-20.09	-32.17	42.70	0.75	0.00	13.68	61.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HRTX	Heron Therapeutics Inc.	581.76	513	17.87	9	1.6	0.79	7.65	1.48	15.04	12.52	22.40	17.28	16.93		0.00	0.00	22.28	25.00	34.00	1,391,969,000	1,001,649	963,682	957,729	-2.50	-1.08	-7.14	-15.37	0.13	1.02	0.61	2.44	3.07	1,333,302,016	-219,716,000	-6.07	15.04	88,638,000	24,611,000	10.41	-227,278,000	91,396,509	79,791,894	20,546,545	19,710,516	23.77	0.27	2.28	208,491,008	-106,924,000	-184,820,000	2.59	6.90	-120,884,000	-251.09	-247.88	-256.41	-136.38	28.13	2.56	0.00	-32.11	-70.99	-41.30	0.98	0.00	0.15	1.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HTBX	Heat Biologics Inc.	397.98	1,108	6.47	6	2.0	-1.67	-12.80	-8.75	0.00	3.50	30.10	8.32	8.76		0.00	0.00	8.38	12.73	19.00	187,780,600	377,158	2,477,043	2,559,452	-1.63	-1.12	-3.97	-5.98	0.13	0.41	0.92	30.61	31.12	77,871,952	-24,592,210	-3.17	26.42	2,947,969	1,848,756	1.60	-26,049,736	25,410,098	24,275,283	2,371,530	2,022,832	2.58	0.10	4.40	111,774,328	-15,669,306	-22,021,360	5.15	1.26	-9,990,926	-845.51	0.00	0.00	-177.03	49.61	5.18	0.00	-20.75	-41.01	-69.80	0.18	0.00	4.15	11.32
HEALTH CARE	Biotechnology	Biotechnology	AMEX	IBIO	iBio Inc.	221.98	2,326	1.23	2	2.0	-4.65	-15.75	-15.75	0.00	0.86	7.45	1.77	2.06		0.00	0.00	2.00	2.50	3.00	349,936,100	4,667,246	9,440,474	17,979,851	-0.18	-0.21	-6.91	-6.14	-0.38	0.84	0.85	17.68	18.17	225,352,800	-19,155,000	-11.77	96.68	2,331,000	32,760,000	30.53	-24,137,000	216,009,931	215,407,263	13,542,334	10,234,416	2.39	0.06	0.50	107,647,000	-16,319,250	-23,142,000	0.51	2.43	1,638,000	-920.72	0.00	0.00	100.00	63.80	5.70	0.00	-14.76	-44.72	124.50	0.02	0.00	0.99	14.18
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ICCC	ImmuCell Corporation	189.12	2,608	9.01	1	2.0	-3.01	-7.40	26.19	0.00	3.80	13.20	10.32	7.02		0.00	0.00	14.00	14.00	14.00	70,395,200	12,407	32,565	24,122	-0.14	-0.11	-63.45	-88.64	2.82	0.52	1.54	4.44	5.50	73,009,368	966,930	75.51	4.76	15,342,204	10,733,167	37.97	-1,022,117	7,220,836	5,165,136	5,581	6,579	0.15	0.00	1.10	7,946,432	-2,155,975	1,315,578	3.92	2.30	6,862,826	-9.00	6.30	-6.66	44.73	25.21	2.75	0.00	-2.18	-3.57	3.10	2.13	0.00	28.83	10.16
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ICPT	Intercept Pharmaceuticals Inc.	205.09	2,471	20.28	22	2.7	-1.31	-8.53	-27.78	0.00	18.15	95.98	24.99	35.04		0.00	0.00	21.00	28.01	41.64	763,651,100	5,353,347	1,166,073	980,429	-8.34	-5.50	-2.43	-3.89	0.07	0.89	-1.22	2.87	3.05	837,803,136	-213,492,000	-3.92	2.68	312,689,984	575,513,984	411.20	-274,880,000	33,015,614	28,140,528	7,508,044	6,405,328	6.49	0.36	14.23	469,667,008	-61,794,000	-170,026,000	-5.05	-4.01	307,368,000	-69.27	-68.28	-87.91	98.30	39.44	3.35	0.00	-20.28	-143,254.91	16.50	9.48	0.00	16.26	82.50
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IDRA	Idera Pharmaceuticals Inc.	44.41	3,872	1.10	2	3.0	1.85	-17.91	-81.48	0.00	1.07	6.14	3.47	3.16		0.00	0.00	1.00	1.50	2.00	60,850,740	2,280,535	3,606,626	1,173,736	-3.33	-0.59	-0.33	-2.27	0.00	0.81	0.24	5.37	5.89	20,280,992	-36,626,000	-0.55	0.00	0	1,384,000	0.00	-112,662,000	42,257,456	26,205,539	2,172,838	481,550	2.79	0.06	0.89	37,728,000	-67,099,248	-33,772,000	-2.38	-0.46	-16,707,000	0.00	0.00	0.00	0.00	61.84	4.52	0.00	-51.02	0.00	0.00	0.00	0.00	26.45	22.60
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IDYA	IDEAYA Biosciences Inc.	600.99	474	18.61	9	1.4	-0.48	-6.29	6.10	0.00	4.36	24.92	20.78	15.32		0.00	0.00	23.00	29.11	33.00	729,075,700	584,366	188,479	198,805	-1.40	-1.73	-13.34	-10.86	-0.56	1.41	1.86	7.39	7.47	307,101,536	-33,963,000	-9.04	15.72	19,538,000	6,723,000	3.39	-34,495,000	32,259,988	17,861,351	604,558	708,988	2.89	0.03	8.80	283,584,992	11,390,000	55,463,000	6.72	2.77	-20,160,000	-180.90	-173.83	-176.55	-103.18	43.38	4.19	0.00	-10.74	-23.10	0.00	0.79	0.00	7.94	63.61
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IGMS	IGM Biosciences Inc.	255.40	2,012	59.69	8	1.6	-4.36	-12.85	-35.60	0.00	41.41	133.00	86.25	73.12		0.00	0.00	77.00	101.63	119.00	2,499,811,000	158,951	203,893	215,148	-26.20	-1.96	-2.28	-31.84	0.02	1.06	0.44	21.25	21.65	1,692,130,560	-82,255,000	-20.57	0.00	0	12,244,000	3.21	-81,355,000	25,574,983	7,887,925	3,564,585	2,142,265	15.12	0.42	11.44	366,268,992	-52,429,000	-67,303,000	8.35	7.15	-39,161,000	0.00	0.00	0.00	0.00	57.75	3.96	0.00	-15.54	-26.16	0.00	0.00	0.00	43.20	68.85
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IMGN	ImmunoGen Inc.	441.77	907	7.52	7	2.1	-2.34	-0.53	-1.70	110.38	3.34	10.88	8.46	6.08		0.00	0.00	6.00	10.21	17.00	1,653,780,000	858,686	2,495,047	2,504,416	-0.25	-0.78	-29.84	-9.64	-0.05	1.45	1.32	2.59	2.65	1,267,969,152	-18,792,000	-67.47	9.58	132,299,000	23,890,000	26.67	-44,372,000	199,731,834	169,837,970	22,350,365	22,893,009	10.90	0.12	1.47	293,856,000	32,865,624	-78,620,000	0.46	16.38	17,707,000	-15.79	-14.20	-33.54	13.38	29.90	3.43	4.08	-4.42	-659.86	91.20	0.75	0.00	0.52	87.65
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IMMP	Immutep Limited	315.08	1,573	3.29	2	2.0	-2.37	-6.80	-0.90	258.51	0.90	7.95	3.03	2.26		0.00	0.00	6.00	7.01	8.00	44,520	949,209	3,248,616	3,231,283	-0.43	-0.27	-7.70	-12.19	0.19	0.69	1.26	11.54	11.94	180,627,840	-17,070,976	-10.58	28.43	6,353,754	9,751,589	16.07	-27,362,032	672,359,314	61,475,154	336,236	65,039	0.06	0.00	0.85	54,880,156	-7,670,624	-14,670,758	0.94	3.50	-6,656,699	-300.79	-268.68	0.00	-166.52	162.43	4.52	0.00	-20.00	-61.68	-76.90	0.14	0.00	0.00	0.37
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IMUX	Immunic Inc.	109.20	3,392	14.21	7	1.6	-7.97	-5.08	-16.12	0.00	7.50	28.21	16.37	16.99		0.00	0.00	14.32	19.10	22.92	312,231,500	233,713	255,093	377,144	-2.81	-3.84	-5.06	-3.90	-0.14	1.23	1.02	15.37	15.93	190,409,552	-48,932,000	-3.89	0.00	0	973,000	0.61	-44,017,000	21,168,240	14,050,419	931,779	897,720	2.55	0.07	6.02	127,452,000	-30,367,876	-46,124,000	7.50	1.89	0	0.00	0.00	0.00	0.00	27.63	4.33	0.00	-26.18	-40.54	0.00	0.00	0.00	31.85	47.08
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INCY	Incyte Corporation	419.35	999	82.68	16	2.2	-0.63	3.40	-11.95	0.00	75.52	110.37	81.44	89.09		0.00	0.00	70.00	104.94	136.00	17,972,210,000	992,777	1,338,709	1,199,977	-1.36	4.57	-60.79	17.99	-1.74	0.84	-0.33	3.62	3.74	15,990,720,512	-187,534,000	-85.27	6.00	2,666,702,080	61,719,000	2.36	-295,696,992	219,843,497	185,844,700	5,910,821	5,532,616	4.61	0.03	8.19	1,801,377,024	-165,885,376	-124,599,000	11.90	6.95	276,631,000	-9.05	-7.03	-11.09	10.37	8.33	1.83	35.40	-4.32	-11.35	36.30	12.23	0.00	1.35	94.30
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INFI	Infinity Pharmaceuticals Inc.	275.74	1,853	2.98	6	2.1	-3.25	-9.97	-21.99	0.00	0.78	5.98	3.38	2.05		0.00	0.00	3.82	4.00	8.50	300,488,700	861,217	4,397,424	1,893,261	-0.68	-0.58	-4.41	-5.31	0.31	1.38	1.64	3.09	3.26	244,372,992	-38,014,000	-6.43	142.16	1,719,000	1,925,000	0.00	-40,492,000	88,639,741	78,209,503	1,182,913	1,239,477	0.50	0.02	0.39	34,108,000	-22,226,750	-35,739,000	-0.36	-8.35	-26,079,000	-2,239.50	-76.24	-77.80	-17.85	35.53	4.22	0.00	-54.48	0.00	41.60	0.03	0.00	2.35	33.30
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INMB	INmune Bio Inc.	22.07	3,987	13.62	3	1.7	26.46	15.72	-33.10	0.00	4.03	29.99	15.34	12.40		0.00	0.00	26.00	29.67	32.00	133,154,699	572,367	218,715	524,580	-1.01	-1.87	-13.50	-6.29	-0.16	1.06	1.44	13.38	13.50	153,950,432	0	0.00	14,103.19	10,916	160,159	0.41	-12,099,159	14,932,638	8,715,136	492,447	447,423	1.96	0.05	1.47	21,966,884	-4,729,582	-8,943,646	2.88	4.74	10,916	-112,016.09	0.00	0.00	100.00	77.13	4.84	0.00	-23.47	-38.80	0.00	0.00	0.00	56.40	14.58
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INO	Inovio Pharmaceuticals Inc.	179.33	2,703	8.74	8	2.6	-3.00	0.23	-3.96	0.00	7.54	33.79	10.63	12.94		0.00	0.00	7.00	11.14	15.63	1,881,003,000	8,876,107	11,736,418	16,813,230	-1.07	0.52	-8.15	16.77	0.05	0.54	0.70	10.33	11.30	1,437,961,856	-120,495,968	-11.93	194.03	7,411,220	39,048,732	8.47	-166,411,152	208,306,017	204,196,265	57,165,836	43,085,502	4.59	0.28	1.98	411,643,040	-109,581,888	-177,979,040	2.47	3.54	-86,834,216	-1,674.25	-189.05	-221.55	-133.26	40.96	5.77	0.00	-22.69	-71.79	1,896.70	0.05	0.00	1.71	32.17
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INSM	Insmed Inc.	346.23	1,383	33.07	9	1.8	-1.64	4.32	-21.41	0.00	17.68	45.44	37.30	34.37		0.00	0.00	41.00	53.56	60.00	3,570,452,000	580,179	973,221	862,136	-3.01	-2.64	-10.98	-12.73	0.89	1.04	1.22	4.62	5.24	3,336,403,200	-254,854,000	-13.09	20.29	164,412,992	404,841,984	146.74	-294,089,984	103,270,236	95,801,461	8,794,028	8,035,575	7.21	0.11	5.17	532,756,000	-107,203,504	-219,348,000	2.69	12.32	124,541,000	-161.32	-155.01	-178.87	75.75	11.10	2.85	0.00	-21.55	-109.42	-9.40	1.68	0.00	1.28	1.06
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IONS	Ionis Pharmaceuticals Inc.	173.72	2,761	40.78	16	2.6	-0.61	-3.73	-33.44	0.00	40.36	64.37	50.97	53.10		0.00	0.00	20.00	56.94	114.00	6,050,032,000	1,860,127	1,344,884	1,061,172	-3.23	-1.29	-12.61	-32.84	0.21	0.85	-0.49	3.39	3.65	4,907,379,200	-126,905,000	-38.67	6.73	729,264,000	839,574,016	99.55	-451,487,008	140,862,211	133,981,092	8,584,561	7,938,627	9.79	0.07	13.48	1,899,117,952	119,941,504	35,892,000	6.01	6.79	182,240,000	-19.52	-17.40	-61.88	24.99	21.55	1.88	0.00	-3.16	-38.51	-41.20	5.22	0.00	5.01	87.31
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IOVA	Iovance Biotherapeutics Inc.	173.68	2,762	30.14	11	1.7	-0.95	-0.17	-36.75	0.00	24.67	54.21	36.43	36.85		0.00	0.00	35.00	52.00	60.00	4,213,895,000	2,099,345	1,951,115	1,436,421	-1.88	-1.89	-16.06	-15.97	-23.18	1.21	-0.00	11.47	11.59	3,859,529,728	-260,796,992	-14.80	0.00	0	51,659,000	7.87	-259,580,992	146,979,253	122,261,752	14,879,674	12,781,421	8.22	0.11	4.28	629,436,992	-148,970,624	-205,134,000	4.47	6.74	0	0.00	0.00	0.00	0.00	14.19	2.80	0.00	-29.42	-54.34	0.00	0.00	0.00	0.64	1.06
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IRWD	Ironwood Pharmaceuticals Inc.	173.26	2,764	10.61	7	2.5	-2.12	4.12	3.41	0.00	8.63	12.55	10.41	10.48		0.00	0.00	9.00	12.29	20.00	1,752,878,000	1,195,217	2,330,722	1,935,152	0.66	1.05	16.07	10.12	-1.66	0.71	0.28	15.07	15.41	1,731,342,592	161,286,000	10.74	4.45	389,523,008	453,702,016	724.30	106,176,000	160,962,175	140,045,140	19,490,262	17,913,413	6.82	0.19	2.25	362,564,000	98,415,504	168,836,000	0.39	27.21	298,325,000	40.80	41.41	27.26	76.59	8.99	2.14	-11.90	20.65	-305.46	-7.60	2.44	0.00	3.09	1.10
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ISEE	IVERIC bio Inc.	356.17	1,328	5.95	3	1.7	-3.57	1.36	10.80	0.00	3.51	7.98	6.14	5.76		0.00	0.00	11.00	13.33	15.00	551,661,700	422,782	520,349	754,500	-1.14	-0.86	-5.22	-6.83	0.21	1.33	0.91	8.43	8.62	319,194,464	-88,593,000	-3.60	0.00	0	115,000	0.06	-84,547,000	90,169,616	63,683,572	5,066,179	6,032,412	8.50	0.06	2.33	210,047,008	-38,038,000	-66,097,000	2.13	2.80	-62,784,000	0.00	0.00	0.00	0.00	37.86	3.27	0.00	-31.97	-54.76	0.00	0.00	0.00	0.78	94.26
HEALTH CARE	Biotechnology	Biotechnology	AMEX	ISR	IsoRay Inc.	96.15	3,508	0.86	3	2.0	-9.47	-19.63	-64.32	0.00	0.35	2.81	1.29	0.87		0.00	0.00	0.95	1.60	2.17	158,143,800	4,078,613	7,796,958	5,603,338	-0.05	-0.03	-18.70	-35.67	0.54	0.37	0.85	8.48	9.21	142,395,904	-3,117,000	-45.68	14.38	9,902,000	897,000	7.02	-3,323,000	141,199,853	139,799,150	2,856,377	2,468,019	0.37	0.02	0.07	9,585,000	-1,905,125	-2,808,000	0.15	5.89	5,124,000	-33.50	-31.48	-33.47	52.41	167.70	4.74	0.00	-16.96	-35.04	6.90	0.14	0.00	0.78	6.18
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	JNCE	Jounce Therapeutics Inc.	364.85	1,272	9.09	5	2.5	-6.39	-7.06	-24.25	0.00	4.30	14.84	11.23	8.36		0.00	0.00	15.00	16.00	20.00	452,573,800	387,700	428,318	686,798	-1.24	-2.10	-7.33	-4.65	-0.11	1.59	1.05	10.69	10.94	230,301,440	-41,716,000	-5.52	3.69	62,339,000	16,889,000	7.99	-43,842,000	50,393,561	34,080,578	1,239,504	618,517	2.00	0.04	4.55	206,478,000	-10,625,125	-27,788,000	5.06	1.80	25,347,000	-72.37	-66.92	-70.33	40.66	55.26	4.22	0.00	-12.53	-22.72	0.00	1.76	0.00	20.51	66.26
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KALV	KalVista Pharmaceuticals Inc.	576.76	523	24.45	7	1.6	-2.98	-6.50	53.48	0.00	9.03	45.00	30.60	18.94		0.00	0.00	48.00	55.43	61.00	680,629,300	319,260	1,314,495	402,451	-2.12	-2.72	-11.55	-9.26	-0.41	1.14	1.06	8.88	9.59	557,164,096	-48,311,000	-11.53	145.70	3,824,000	1,715,000	2.93	-37,872,000	24,308,191	21,282,794	1,181,645	782,353	2.72	0.06	2.07	50,311,000	-22,288,750	-31,744,000	3.25	7.52	-27,504,000	-1,277.14	0.00	0.00	0.00	114.13	3.82	0.00	-36.09	-51.07	0.00	0.21	0.00	6.57	67.46
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KDMN	Kadmon Holdings Inc.	139.28	3,105	3.92	6	1.7	-0.51	7.10	-19.01	0.00	3.15	5.73	4.41	4.22		0.00	0.00	8.00	3.87	6.37	661,495,200	2,940,475	3,719,215	2,789,812	-0.67	-0.24	-5.87	-16.42	0.09	0.94	0.15	4.60	4.66	609,951,744	-100,638,000	-6.06	73.60	8,288,000	22,860,000	19.70	-111,035,000	171,816,945	137,221,603	41,656,251	33,739,990	11.01	0.26	0.78	134,422,000	-50,932,752	-87,529,000	0.42	9.40	6,287,000	-1,234.09	0.00	0.00	75.86	13.49	3.16	0.00	-33.87	-77.31	-78.90	0.05	0.00	0.14	97.56
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KIN	Kindred Biosciences Inc.	314.98	1,574	4.85	7	2.0	-2.41	-5.46	8.99	0.00	3.20	6.00	4.87	4.39		0.00	0.00	5.09	9.00	11.18	190,251,900	181,319	426,204	335,812	-0.56	-0.69	-8.74	-7.43	-0.36	1.24	0.52	8.56	9.08	177,628,496	-50,552,000	-3.51	51.28	3,464,000	23,372,000	34.63	-21,796,000	41,449,218	28,775,705	1,076,393	992,496	3.32	0.03	1.41	58,378,000	-27,378,250	-9,857,000	1.71	2.84	-1,162,000	-1,571.07	0.00	0.00	-33.55	18.33	3.39	0.00	-32.42	-29.18	-32.10	0.09	0.00	5.82	75.84
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KMDA	Kamada Ltd.	268.20	1,915	6.17	2	2.0	-2.53	0.49	-8.46	0.00	5.78	13.33	6.43	7.54		0.00	0.00	11.00	11.00	11.00	0	44,348	194,738	283,300	0.38	0.10	16.24	63.30	-0.23	0.45	0.13	5.30	7.13	178,911,152	23,123,000	7.74	1.34	133,246,000	4,939,000	2.77	17,140,000	44,742,963	28,550,227	968,912	1,002,224	8.19	0.03	2.44	109,266,000	5,843,125	19,105,000	3.99	1.55	47,552,000	14.44	17.35	12.86	35.69	17.34	2.60	-72.90	6.26	10.92	-1.60	3.02	0.00	16.60	40.38
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KNSA	Kiniksa Pharmaceuticals Ltd.	223.22	2,315	15.63	5	1.6	-4.93	-11.65	-10.53	0.00	14.51	28.67	20.33	18.82		0.00	0.00	25.00	34.20	40.00	1,138,797,000	838,078	608,553	438,304	-2.61	-2.53	-5.99	-6.21	1.95	1.33	0.11	10.16	10.46	890,532,480	-154,958,000	-5.75	0.00	0	6,985,000	2.24	-161,380,992	31,922,546	26,814,613	3,654,435	3,788,523	7.65	0.13	4.74	323,481,984	-73,268,872	-136,532,000	4.57	3.42	0	0.00	0.00	0.00	0.00	18.37	3.36	0.00	-32.57	-60.07	0.00	0.00	0.00	7.09	94.56
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KOD	Kodiak Sciences Inc	88.37	3,569	114.89	10	2.6	-0.71	5.34	-27.29	0.00	42.97	171.21	126.38	99.53		0.00	0.00	89.00	138.40	190.00	5,951,725,000	175,904	315,114	331,447	-2.91	-6.31	-39.48	-18.33	-0.34	1.53	1.48	30.84	30.93	4,649,454,592	-135,530,000	-34.31	0.00	0	77,402,000	8.99	-133,096,000	51,162,424	31,889,224	3,330,626	3,236,464	10.13	0.11	19.07	968,974,016	-39,604,000	-83,428,000	16.96	6.77	0	0.00	0.00	0.00	0.00	13.47	3.31	0.00	-11.92	-22.07	0.00	0.00	0.00	10.99	86.22
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KPTI	Karyopharm Therapeutics Inc.	145.69	3,050	9.71	9	1.7	0.21	-3.09	-35.53	0.00	9.64	25.98	12.47	15.01		0.00	0.00	21.00	9.55	15.60	768,733,200	1,400,236	2,364,286	1,956,540	-2.72	-0.92	-3.56	-10.53	0.05	1.19	-1.18	4.35	4.59	605,096,256	-170,878,000	-3.54	5.60	108,085,000	131,130,000	259.43	-196,272,992	75,061,474	62,462,931	15,480,927	16,758,753	6.95	0.22	3.34	249,240,000	-88,158,752	-160,234,000	0.68	14.20	-45,433,000	-159.00	-158.10	-181.59	-42.04	12.45	2.93	0.00	-35.33	-391.29	94.00	1.50	0.00	9.30	87.33
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KRTX	Karuna Therapeutics Inc.	134.57	3,148	112.60	13	1.5	-4.00	-3.69	12.23	0.00	69.58	146.97	119.11	97.91		0.00	0.00	130.00	159.31	192.00	3,309,533,000	184,865	226,429	177,303	-1.90	-2.80	-59.23	-41.75	-1.25	1.20	0.96	47.04	50.28	2,839,115,264	-69,671,000	-40.75	0.00	0	2,685,000	0.79	-68,554,000	29,102,068	19,889,030	1,659,112	1,460,202	6.54	0.13	11.93	322,329,984	-46,347,000	-69,856,000	6.94	16.22	0	0.00	0.00	0.00	0.00	11.08	2.60	0.00	-11.78	-18.81	0.00	0.00	0.00	9.92	83.03
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KRYS	Krystal Biotech Inc.	212.84	2,405	77.33	10	1.8	0.95	11.60	11.07	0.00	37.68	87.29	75.30	56.14		0.00	0.00	54.00	98.80	125.00	1,530,106,000	141,784	149,691	143,453	-1.71	-3.02	-45.17	-23.75	-0.59	1.26	1.18	17.56	17.80	1,270,558,336	-31,148,000	-40.79	0.00	0	3,946,000	1.35	-32,167,000	22,203,807	15,425,131	1,236,113	1,186,134	8.30	0.07	12.22	271,262,016	-19,978,376	-26,083,000	14.82	5.22	0	0.00	0.00	0.00	0.00	14.19	2.91	0.00	-7.93	-13.00	0.00	0.00	0.00	24.77	64.30
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KURA	Kura Oncology Inc.	183.66	2,665	28.59	8	1.9	-2.99	0.07	-16.55	0.00	9.89	43.00	29.91	29.55		0.00	0.00	30.00	41.63	53.00	1,813,525,000	389,824	776,016	719,419	-1.69	-2.01	-16.93	-14.21	-0.89	1.13	1.63	24.34	24.49	1,273,311,360	-91,705,000	-13.89	0.00	0	14,977,000	2.45	-89,625,000	66,211,215	60,176,725	9,103,888	6,072,765	8.97	0.16	9.57	633,320,000	-42,355,124	-69,830,000	9.23	3.10	0	0.00	0.00	0.00	0.00	48.27	3.15	0.00	-12.92	-21.61	0.00	0.00	0.00	3.21	99.20
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KZR	Kezar Life Sciences Inc.	111.98	3,367	5.74	3	1.6	-3.53	-4.97	7.49	0.00	4.15	9.79	6.07	5.43		0.00	0.00	12.00	15.00	5.73	296,569,300	113,273	331,521	243,661	-0.95	-1.23	-6.05	-4.84	-0.20	0.67	0.65	21.92	22.48	151,011,744	-41,406,000	-3.65	0.00	0	5,464,000	3.88	-41,742,000	48,066,343	33,399,379	2,037,784	1,756,455	9.32	0.05	2.92	140,447,008	-21,691,750	-36,949,000	3.04	1.89	0	0.00	0.00	0.00	0.00	73.27	3.45	0.00	-22.24	-38.12	0.00	0.00	0.00	30.51	53.10
HEALTH CARE	Biotechnology	Biotechnology	AMEX	LCTX	Lineage Cell Therapeutics Inc.	309.36	1,603	2.29	6	2.1	1.33	-11.24	-17.03	0.00	0.70	3.13	2.46	1.60		0.00	0.00	2.23	4.00	5.33	383,081,800	647,513	1,589,570	1,207,946	-0.37	-0.18	-6.14	-12.56	0.12	0.73	1.69	5.42	5.66	329,725,376	-23,708,000	-13.91	180.57	1,826,000	3,825,000	4.02	-20,649,000	161,637,890	120,407,297	5,333,427	3,847,885	3.18	0.04	0.26	41,562,000	13,880,125	-19,753,000	0.78	2.93	1,441,000	-1,410.02	0.00	0.00	78.92	26.89	4.04	0.00	-13.79	-20.05	-71.40	0.01	0.00	4.63	34.10
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LGND	Ligand Pharmaceuticals Incorporated	395.08	1,119	150.23	7	2.1	0.91	-2.09	11.37	0.00	78.26	219.75	157.72	118.80		0.00	0.00	198.00	221.14	310.00	2,549,675,000	110,142	338,864	384,860	-0.18	4.70	-816.47	31.68	0.31	0.84	1.10	4.70	5.00	2,518,597,376	57,397,000	43.88	13.51	186,419,008	456,526,016	64.34	-2,985,000	16,612,422	15,809,876	1,501,423	2,212,675	5.67	0.15	24.75	411,185,984	120,217,872	54,586,000	44.13	3.40	96,608,000	15.79	30.79	-1.60	51.82	17.35	2.61	0.00	1.29	-0.40	159.20	11.52	0.00	4.77	1.40
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LIFE	aTyr Pharma Inc.	364.45	1,276	3.77	3	1.7	1.89	-16.22	-3.83	0.00	2.87	8.33	4.93	4.15		0.00	0.00	4.14	4.99	6.37	74,132,710	527,095	1,792,361	718,688	-1.77	-2.23	-2.13	-2.02	-0.08	0.95	0.70	5.41	6.06	42,435,232	-15,342,000	-2.77	4.06	10,455,000	2,239,000	7.11	-16,224,000	16,011,385	13,322,913	337,261	159,766	0.45	0.02	1.98	31,689,000	-8,558,375	-15,301,000	2.87	1.31	-6,836,000	-152.19	-146.74	-155.18	-65.39	45.38	4.15	0.00	-26.55	-61.82	1,325.70	1.14	0.00	3.96	45.82
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LJPC	La Jolla Pharmaceutical Company	188.56	2,616	4.07	3	2.5	-2.63	-0.25	-25.87	0.00	3.36	8.10	5.25	4.60		0.00	0.00	4.77	5.00	9.33	122,605,000	181,895	299,237	547,986	-1.44	0.29	-2.82	14.07	0.02	1.02	-0.27	2.19	2.96	221,867,904	-23,022,000	-9.64	6.64	33,419,000	127,275,000	0.00	-39,421,000	27,428,407	14,088,601	2,986,678	2,398,147	9.41	0.16	0.77	21,221,000	-27,435,500	-37,640,000	-3.36	-1.21	28,058,000	-77.37	-68.89	-117.96	83.96	28.08	3.60	0.00	-15.81	0.00	51.00	1.22	0.00	1.47	77.36
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LOGC	LogicBio Therapeutics Inc.	164.36	2,872	5.88	4	1.6	-5.47	-4.55	-30.74	0.00	5.00	10.00	7.80	7.44		0.00	0.00	6.45	7.64	17.00	225,142,500	166,765	131,713	139,683	-1.29	-1.12	-4.57	-5.50	0.35	1.54	0.54	11.43	11.79	143,269,952	-31,036,000	-4.62	41.48	3,454,000	16,065,000	26.15	-32,621,000	32,025,966	17,403,550	824,401	677,650	5.63	0.04	2.19	70,075,000	-17,517,624	-28,925,000	1.93	3.04	3,454,000	-912.31	0.00	0.00	100.00	31.75	4.08	0.00	-28.90	-62.91	0.00	0.14	0.00	13.64	65.19
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LPTX	Leap Therapeutics Inc.	242.50	2,132	1.65	5	1.6	-2.37	-8.33	-31.82	0.00	1.43	3.24	2.28	2.05		0.00	0.00	1.69	2.55	3.50	118,122,300	574,024	898,060	819,208	-0.63	-0.57	-2.60	-3.16	0.26	0.79	0.36	7.07	7.09	55,864,936	-28,274,000	-1.98	37.24	1,500,000	552,000	1.18	-37,588,000	59,657,742	37,281,913	1,424,292	1,059,424	1.99	0.03	0.87	52,071,000	-15,876,875	-25,957,000	0.78	2.11	1,500,000	-1,887.20	0.00	0.00	100.00	30.43	3.64	0.00	-57.24	-122.55	0.00	0.03	0.00	12.04	54.00
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LXRX	Lexicon Pharmaceuticals Inc.	363.56	1,279	5.05	3	2.7	-3.07	-5.96	-40.45	0.00	1.03	9.65	6.76	3.59		0.00	0.00	6.00	9.00	13.00	848,802,500	924,476	1,281,435	4,556,811	-0.53	-0.45	-9.53	-11.93	0.63	0.88	1.19	3.26	3.37	631,458,432	-171,551,008	-3.68	26.32	23,995,000	12,810,000	8.19	-58,574,000	144,354,161	55,400,252	4,906,403	4,485,005	3.58	0.07	1.06	152,275,008	101,607,872	-142,968,992	1.11	4.57	-129,055,000	-722.17	25.76	-244.11	43.06	104.69	4.27	0.00	-34.85	-42.84	-97.70	0.22	0.00	4.12	88.22
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MACK	Merrimack Pharmaceuticals Inc.	20.51	3,992	7.02	1	3.5	-0.28	14.15	-6.65	0.00	3.06	9.45	6.92	5.29		0.00	0.00	4.00	4.00	4.00	87,166,580	54,219	91,884	503,331	-0.23	-1.78	-31.06	-3.46	-0.05	0.72	1.20	18.23	21.49	68,434,992	-2,784,000	-24.58	0.00	0	0	0.00	-3,028,000	13,410,243	8,092,143	455,373	589,421	4.67	0.04	1.05	14,038,000	-1,665,500	-4,625,000	1.20	5.87	-9,100,000	0.00	0.00	0.00	0.00	58.66	2.85	0.00	-17.00	-18.18	0.00	0.00	0.00	3.23	64.93
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MBIO	Mustang Bio Inc.	160.22	2,910	3.05	4	1.7	-3.79	-4.39	-36.46	0.00	2.42	5.22	3.60	3.46		0.00	0.00	3.26	4.14	7.00	275,966,300	1,586,902	2,426,868	2,300,402	-1.14	-0.77	-2.67	-4.14	0.08	1.72	0.45	10.28	10.46	175,167,872	-55,129,000	-3.18	0.00	0	2,228,000	2.26	-60,015,000	84,329,415	69,818,818	2,954,810	2,988,243	1.07	0.05	1.15	97,804,000	-32,377,876	-37,319,000	1.38	2.21	0	0.00	0.00	0.00	0.00	29.36	3.61	0.00	-38.73	-79.97	0.00	0.00	0.00	17.45	25.47
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MBRX	Moleculin Biotech Inc.	140.25	3,095	3.44	3	1.7	-5.23	-9.24	-46.42	0.00	3.16	9.30	4.27	5.03		0.00	0.00	2.90	4.46	6.47	108,942,100	985,757	2,418,325	1,282,988	-1.76	-0.85	-1.95	-4.46	0.04	0.81	-0.38	5.20	5.89	92,908,368	-19,542,000	-4.75	0.00	0	277,000	1.56	-17,355,000	28,444,425	27,870,701	300,746	416,454	0.26	0.01	0.53	15,173,000	-10,770,750	-17,771,000	1.54	2.24	0	0.00	0.00	0.00	0.00	36.51	3.26	0.00	-45.48	-104.14	0.00	0.00	0.00	4.09	7.72
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MCRB	Seres Therapeutics Inc.	0.00	4,019	20.73	7	1.9	-3.09	0.73	-14.23	479.72	3.41	38.50	21.49	22.84		0.00	0.00	24.00	37.57	47.00	1,727,537,000	663,136	1,052,996	1,609,648	-1.12	-1.30	-18.56	-15.51	-1.13	1.80	1.09	5.67	5.79	1,671,239,936	-81,552,000	-20.49	50.32	33,215,000	40,769,000	23.33	-89,127,000	91,549,412	68,319,664	7,233,352	5,959,586	5.65	0.13	2.77	253,616,000	-52,130,752	-93,610,000	1.91	10.85	-57,355,000	-265.33	-245.53	-268.33	-172.68	387.51	5.94	0.00	-23.17	-140.99	130.40	0.42	0.00	9.23	88.74
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MDGL	Madrigal Pharmaceuticals Inc.	264.69	1,941	124.77	13	2.1	-1.48	6.62	14.10	0.00	78.92	137.28	118.41	115.97		0.00	0.00	126.00	171.54	225.00	1,864,151,000	132,412	160,398	151,120	-13.09	-14.83	-9.53	-7.89	-0.72	0.65	1.13	6.10	6.13	1,591,844,992	-206,202,000	-7.72	0.00	0	786,000	0.33	-202,244,000	16,024,680	7,180,980	2,455,942	2,768,533	17.13	0.29	17.73	284,148,992	-86,741,624	-157,560,992	15.47	8.06	0	0.00	0.00	0.00	0.00	13.41	2.18	0.00	-35.44	-61.61	0.00	0.00	0.00	18.79	94.57
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MDXG	MiMedx Group Inc	316.57	1,563	11.66	2	2.0	-5.20	-8.33	32.20	0.00	3.30	12.87	10.37	7.75		0.00	0.00	16.00	18.00	20.00	1,090,359,000	496,754	552,415	534,670	-0.77	-0.15	-15.14	-82.00	0.19	0.33	1.85	2.39	2.72	1,365,339,392	-37,516,000	-36.39	5.50	248,234,000	51,833,000	56.70	-83,328,000	111,261,154	74,065,643	6,109,139	7,574,756	9.86	0.07	0.88	95,812,000	-27,030,376	-30,263,000	-0.00	-11,660.00	208,904,000	-17.88	-15.11	-19.85	84.16	31.76	3.11	0.00	-15.02	-78.34	-10.30	2.29	0.00	3.89	44.30
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MEIP	MEI Pharma Inc.	553.01	573	3.38	10	1.8	-3.70	-1.74	17.36	105.99	2.28	4.58	3.70	3.14		0.00	0.00	4.14	5.50	9.60	396,098,100	540,886	997,861	975,333	-0.53	-0.49	-6.43	-6.92	0.94	0.82	0.83	5.15	5.24	215,666,832	-34,403,000	-6.27	5.43	39,749,000	8,715,000	11.86	-36,351,000	112,527,860	90,679,451	9,706,941	8,487,673	12.17	0.09	1.60	180,144,000	635,125	53,756,000	0.65	5.18	26,242,000	-87.03	-86.55	-91.45	94.10	18.42	3.33	0.00	-13.91	-48.22	809.40	0.36	0.00	2.82	69.36
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MESO	Mesoblast Limited	177.22	2,725	8.94	6	2.5	-0.67	5.05	-5.70	0.00	6.09	21.28	9.28	12.33		0.00	0.00	6.00	14.42	23.00	1,120,951,000	74,426	280,332	742,779	-0.87	-0.41	-10.28	-21.22	0.19	1.23	0.80	0.88	0.99	1,021,272,896	-109,798,000	-9.30	62.09	16,448,000	99,721,000</