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Health Care

SECTOR	industry1	INDUSTRY	EXCH	SYM	NAME	42s WEIGHT	42s RANK	PRICE	# OPINION	REC MEAN	1d %	1w %	12w %	52w %	52w LOW	52w HI	50d AVG	200d AVG	EX-DIV	DIV RATE	DIV YLD	$ TGT LOW	$ TGT AVG	$ TGT HI	MKT CAP	VOLUME	50d VOL	200d VOL	EPS	FW EPS	P/E	FW P/E	PE/G	GROWTH	BETA	SHARPE	QK RATIO	CUR RATIO	E/V	EBITDA	EV/EBITDA	EV/R	REVENUE	DEBT	DEBT/EQTY	INCOME	SHRS OSTDG	FLT SHRS	SHRS SHRT	SHRS SHRT PR MO	SHRT RATIO	SHORT %	CSH/SHR	SUM CASH	FREE CASH	OPTG CASH	BOOK	PR/BK	PROFIT	OP MRGN	EBITDA MRGN	PFT MRGN	GRS MRGN	MAX VLTY	AVG VLTY	EARN GRW	ROA	ROE	REV GRW	REV/SHARE	REV/QTR GRW	% INSDR	% INST
HEALTH CARE	--	--	--	--	2021-01-26 . sector average -->	229.35	1,319	180.44	15	2.0	-0.89	0.18	15.32	29.22	96.28	194.94	170.98	155.99		1.76	1.43	147.68	190.90	221.92	6,913,779,827,687	2,161,484,476	1,809,542,766	1,332,251,905	5.02	7.88	-4.85	32.93	2.29	0.00	0.00	1.25	2.42	2.88	7,583,606,090,980	349,545,813,767	18.79	288.73	2,792,811,351,218	1,207,324,039,333	134.73	120,684,381,490	104,990,708,184	64,685,620,997	3,774,560,322	3,677,209,597	3.09	0.02	12.55	522,035,316,861	157,944,718,531	291,349,852,463	5,610.18	8.25	1,080,597,014,976	-776.48	17.06	6.07	52.22	1.92	0.18	0.18	3.87	-3.60	52.31	64.79	0.00	2.78	69.16
HEALTH CARE	Biotechnology	Biotechnology	--	--	2021-01-26 . industry average -->	271.77	999	150.32	17	2.1	-1.68	-0.04	26.52	71.99	82.96	175.06	137.92	132.06		1.68	1.22	117.15	161.02	202.13	1,365,654,296,395	1,004,468,862	683,780,050	597,871,524	2.90	6.75	87.64	111.61	21.54	0.00	0.00	2.06	5.30	5.70	1,393,586,206,066	28,614,301,246	-13.21	426.11	156,068,974,807	189,487,109,875	158.18	-521,035,123	32,679,651,814	19,062,660,281	2,055,108,417	2,070,049,129	4.51	0.05	13.05	151,941,370,492	24,807,421,349	33,169,747,559	1,350.87	10.95	92,479,202,202	-1,700.69	-9.26	-18.44	34.33	3.35	0.39	1.85	-4.30	-101.92	186.34	19.39	0.00	5.02	71.88
HEALTH CARE	Biotechnology	Biotechnology	NYSE	ABBV	AbbVie Inc.	256.39	760	108.80	21	2.0	-1.54	-3.01	23.69	31.94	62.55	113.41	105.52	94.71	2021-01-14	5.20	4.69	97.00	117.10	135.00	195,084,900,000	5,554,641	7,407,862	8,358,182	4.57	12.19	23.79	9.06	1.06	0.00	0.71	0.92	0.68	0.95	274,874,433,536	18,371,999,744	14.96	6.76	40,649,998,336	87,098,998,784	569.68	7,324,000,256	1,765,473,923	1,741,887,191	13,334,764	13,270,647	1.87	0.01	4.51	7,964,000,256	13,844,500,480	16,008,999,936	8.65	12.58	25,827,000,000	33.11	45.20	18.16	68.87	1.66	0.12	2.40	8.05	209.12	52.20	25.47	0.00	0.10	70.00
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ABEO	Abeona Therapeutics Inc.	154.09	1,665	2.24	4	1.7	-3.86	4.67	113.33	-10.92	0.99	4.34	1.64	2.19		0.00	0.00	2.55	3.00	5.00	229,569,600	3,911,158	2,461,253	1,660,102	-1.02	-0.61	-2.21	-3.48	0.06	0.00	1.12	0.51	2.68	2.70	120,991,776	-44,617,000	-2.71	17.29	7,000,000	8,984,000	7.81	-84,837,000	98,527,723	77,916,709	2,682,541	1,364,705	1.15	0.03	0.98	96,871,000	-10,207,250	-47,655,000	1.36	1.64	-48,566,000	-720.50	0.00	0.00	0.00	3.84	0.04	0.00	-20.87	-80.35	0.00	0.08	0.00	16.22	37.93
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ABIO	ARCA biopharma Inc.	51.51	3,537	4.51	0	0.0	0.67	-5.05	12.19	-19.28	2.21	22.00	4.23	5.18		0.00	0.00	0.00	0.00	0.00	41,760,190	415,469	529,301	1,041,068	-2.11	-8.80	-2.14	-0.51	-0.01	0.00	0.42	0.63	33.46	34.01	-9,334,814	-5,910,000	1.58	0.00	0	0	0.24	-5,839,000	9,321,470	9,284,371	126,649	49,824	0.24	0.01	5.48	51,095,000	-3,749,375	-5,888,000	5.43	0.83	0	0.00	0.00	0.00	0.00	0.74	0.07	0.00	-11.95	-19.71	0.00	0.00	0.00	0.40	8.43
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ABUS	Arbutus Biopharma Corporation	250.29	807	3.82	6	2.0	-4.74	-6.14	32.18	37.29	0.88	9.02	3.92	2.89		0.00	0.00	4.00	7.00	10.00	340,486,100	3,109,952	4,007,523	4,445,710	-1.21	-0.83	-3.17	-4.88	0.10	0.00	0.86	0.86	15.69	15.94	367,340,672	-47,779,000	-7.69	59.77	6,146,000	3,111,000	3.20	-83,237,000	84,909,258	59,105,334	4,818,263	2,138,117	0.87	0.07	1.39	118,296,000	-27,120,624	-49,779,000	-0.58	-6.61	-51,590,000	-809.91	0.00	0.00	0.00	4.86	0.14	0.00	-25.05	-78.86	-50.20	0.09	0.00	21.23	30.96
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ACAD	ACADIA Pharmaceuticals Inc.	250.60	801	51.61	20	1.7	-4.34	-3.30	10.75	30.67	30.02	58.72	53.82	47.63		0.00	0.00	42.00	61.70	72.00	8,576,868,000	991,563	902,283	1,305,001	-1.72	-1.03	-30.09	-51.29	0.75	0.00	0.80	0.73	7.54	7.95	7,803,571,200	-220,294,000	-35.42	18.62	419,073,984	49,200,000	7.51	-267,860,000	158,978,087	116,702,634	6,330,637	7,835,391	6.87	0.07	4.05	644,441,024	-62,610,376	-138,384,992	4.12	12.52	79,093,000	-53.22	-52.57	-63.92	32.63	4.45	0.13	0.00	-17.86	-39.86	27.50	2.68	0.00	0.38	96.17
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ACHV	Achieve Life Sciences Inc.	272.14	681	13.09	5	1.7	3.40	30.12	61.81	5.18	4.60	18.26	8.80	8.72		0.00	0.00	10.00	14.32	21.00	73,002,800	398,670	407,851	1,093,710	-7.40	-5.30	-1.77	-2.22	0.06	0.00	0.71	0.63	12.12	13.02	20,435,082	-12,985,000	-1.57	0.00	0	212,000	0.83	-13,200,000	3,617,664	3,195,012	482,617	528,984	1.73	0.08	6.19	22,393,000	-9,677,750	-14,408,000	7.10	1.84	0	0.00	0.00	0.00	0.00	3.33	0.08	0.00	-42.31	-78.07	0.00	0.00	0.00	0.48	15.13
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ACIU	AC Immune SA	157.09	1,631	6.79	4	1.7	3.98	9.87	42.65	-25.80	4.07	13.00	5.50	6.45		0.00	0.00	5.00	12.24	17.00	468,470,600	229,497	316,107	523,490	-0.55	-0.57	-12.41	-11.91	-2.95	0.00	0.83	0.18	17.90	18.10	469,670,304	0	0.00	0.00	0	0	0.96	0	71,859,431	28,753,461	1,280,141	1,473,915	3.71	0.05	0.00	0	0	0	2.99	2.27	60,594,000	0.00	0.00	0.00	-265.63	4.07	0.10	0.00	-13.25	-23.54	-96.60	0.00	0.00	46.99	29.82
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ACOR	Acorda Therapeutics Inc.	255.78	766	7.45	3	2.7	0.13	-6.52	14.97	-41.23	2.52	13.62	4.90	4.62		0.00	0.00	4.00	7.32	11.14	70,555,280	389,529	1,368,956	1,017,350	5.32	-7.32	1.40	-1.02	-0.01	0.00	0.90	0.08	0.55	1.09	252,470,016	-40,837,000	-6.18	1.53	165,304,000	256,290,000	81.74	49,114,000	9,483,236	7,209,774	417,022	1,386,893	0.69	0.05	7.92	63,257,000	-68,945,504	-73,883,000	39.43	0.19	157,559,000	-49.02	-24.70	29.71	100.63	0.30	0.17	0.00	-6.37	16.51	11.20	20.81	0.00	1.69	49.59
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADAP	Adaptimmune Therapeutics plc	65.50	3,256	5.59	6	2.4	-2.78	-5.89	6.88	38.02	2.00	13.40	5.09	6.89		0.00	0.00	6.00	11.33	5.41	889,977,900	797,201	1,645,966	1,867,944	-0.95	-0.95	-5.92	-5.88	-11.18	0.00	1.06	0.83	11.86	12.23	513,778,880	-118,285,000	-4.34	161.36	3,184,000	23,709,000	6.30	-122,843,000	927,968,286	74,035,326	3,701,437	2,815,864	1.75	0.00	2.58	399,908,000	-48,814,376	-36,903,000	2.43	2.30	-96,379,000	-3,965.04	0.00	0.00	0.00	2.99	0.22	0.00	-22.96	-46.90	403.40	0.02	0.00	0.22	84.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADMA	ADMA Biologics Inc	184.67	1,303	2.46	6	1.8	-0.41	9.82	18.27	-41.59	1.45	4.25	2.08	2.53		0.00	0.00	2.81	3.50	6.00	233,533,700	4,351,130	3,548,978	4,043,402	-0.87	-0.46	-2.82	-5.28	0.06	0.00	0.62	0.01	4.01	8.47	270,256,992	-51,983,016	-5.20	6.71	40,300,744	100,180,280	140.36	-66,901,804	94,548,052	76,071,472	11,585,590	11,947,854	2.92	0.16	0.63	59,675,044	-73,810,384	-89,435,560	0.80	3.09	-10,155,155	-137.77	-128.99	-166.01	-33.68	0.24	0.16	0.00	-21.18	-124.48	42.30	0.53	0.00	2.13	54.51
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADMS	Adamas Pharmaceuticals Inc.	114.49	2,270	5.62	8	2.2	10.63	24.34	61.03	-10.44	1.90	6.02	4.61	3.81		0.00	0.00	3.00	6.05	9.19	144,884,200	1,910,723	209,420	381,203	-2.21	-1.22	-2.54	-4.16	0.06	0.00	0.95	0.52	3.18	3.94	188,279,856	-45,930,000	-4.10	2.70	69,799,000	146,140,000	0.00	-62,205,000	28,520,519	19,209,425	1,249,994	1,161,910	6.64	0.05	3.24	92,477,000	-49,011,876	-58,694,000	-1.21	-4.63	52,168,000	-67.12	-65.80	-89.12	97.30	10.60	0.07	0.00	-18.69	0.00	44.80	2.48	0.00	2.74	68.33
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADVM	Adverum Biotechnologies Inc.	140.78	1,857	12.89	9	2.1	-6.39	5.92	6.35	19.66	7.36	26.98	12.75	14.98		0.00	0.00	13.00	25.22	36.00	1,342,267,000	670,214	1,056,192	1,207,700	-1.28	-1.39	-10.05	-9.63	-1.20	0.00	1.41	0.63	28.21	28.53	881,950,080	-97,788,000	-9.02	0.00	0	31,187,000	6.71	-98,800,000	97,477,603	66,973,937	10,273,180	12,352,200	9.09	0.11	4.66	454,462,016	-63,196,376	-71,902,000	4.77	2.70	-40,169,000	0.00	0.00	0.00	0.00	6.45	0.09	0.00	-17.74	-31.42	0.00	0.00	0.00	0.75	96.25
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ADXS	Advaxis Inc.	38.33	3,773	0.78	0	2.0	2.63	8.33	116.67	-9.04	0.26	1.26	0.43	0.52		0.00	0.00	0.00	0.00	0.00	85,053,690	15,404,844	12,210,370	4,208,847	-0.43	-0.55	-1.80	-1.38	-0.07	0.00	0.94	0.51	7.65	8.46	64,302,696	-22,430,000	-2.87	254.16	253,000	6,017,000	19.94	-26,469,000	92,894,139	105,847,956	1,241,529	600,593	0.14	0.01	0.23	25,178,000	-13,103,000	-21,940,000	0.39	2.02	253,000	-9,353.36	0.00	0.00	100.00	2.31	0.03	0.00	-35.31	-75.94	-100.00	0.00	0.00	0.09	17.72
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AEZS	Aeterna Zentaris Inc.	50.95	3,547	0.68	0	0.0	3.03	-1.45	112.50	-40.83	0.29	1.38	0.47	0.58		0.00	0.00	0.00	0.00	0.00	40,840,990	14,402,597	5,966,187	3,471,359	-0.16	1.78	-4.30	0.37	0.00	0.00	0.93	0.14	12.57	12.98	22,812,654	-6,977,000	-3.27	17.49	1,304,000	201,000	1.33	-4,813,000	62,678,613	62,626,590	2,337,073	1,473,357	0.81	0.04	0.35	21,746,000	-6,132,250	-9,601,000	0.24	2.81	122,000	-533.67	0.00	0.00	6.75	2.39	0.18	0.00	-16.18	-74.30	-54.80	0.04	0.00	6.29	4.44
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AFMD	Affimed N.V.	306.09	536	6.03	5	1.6	-8.08	-13.24	84.40	135.97	1.42	7.48	6.00	4.05		0.00	0.00	8.04	9.65	11.06	688,752,100	1,986,206	1,756,552	1,343,721	-0.72	-0.41	-8.41	-14.71	0.20	0.00	1.06	1.36	2.21	2.24	579,418,816	0	0.00	0.00	0	0	5.08	0	117,286,342	82,395,830	6,163,449	5,667,975	3.66	0.07	0.00	0	0	0	0.67	9.01	21,410,000	0.00	-154.33	-175.03	100.00	8.56	0.51	0.00	-22.94	-114.04	401.40	0.00	0.00	6.41	55.27
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AGEN	Agenus Inc.	75.88	3,066	3.71	2	1.3	-4.87	5.70	-4.13	-7.28	1.82	5.63	3.50	3.63		0.00	0.00	8.00	8.00	8.00	741,582,300	3,055,319	2,230,114	2,649,777	-1.09	-1.06	-3.39	-3.25	1.12	0.00	0.78	0.39	0.79	0.85	596,789,056	-98,524,000	-6.06	6.53	91,406,000	37,737,000	0.00	-173,571,008	190,149,301	143,172,916	24,529,990	22,388,920	9.80	0.14	0.60	114,144,000	-59,146,124	-135,286,000	-1.05	-3.54	-18,291,000	-115.45	-107.79	-189.66	-59.10	5.00	0.02	0.00	-34.78	0.00	-25.60	0.58	0.00	10.26	53.96
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AGIO	Agios Pharmaceuticals Inc.	358.27	382	48.04	10	1.7	-2.95	3.20	15.90	-9.91	27.77	56.75	42.81	43.64		0.00	0.00	51.00	65.00	80.00	3,428,361,000	554,728	865,332	732,906	-4.91	-5.66	-9.79	-8.39	-0.64	0.00	0.82	0.17	9.01	9.59	2,789,523,456	-320,374,016	-8.71	14.34	194,591,008	107,299,000	22.33	-332,063,008	69,259,817	61,415,450	5,842,796	4,956,587	5.35	0.13	8.74	605,539,008	-197,059,744	-334,972,992	6.94	6.92	-294,299,000	-169.40	-164.64	-170.65	-95.34	2.91	0.05	0.00	-25.64	-71.51	33.40	2.88	0.00	11.33	92.34
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AGLE	Aeglea BioTherapeutics Inc.	155.29	1,653	7.38	8	2.1	-3.40	-6.46	-5.63	5.23	3.50	11.38	8.35	7.89		0.00	0.00	8.28	9.00	15.63	366,239,500	151,583	197,779	274,429	-1.76	-1.32	-4.20	-5.59	0.17	0.00	1.56	0.48	9.76	10.06	231,640,496	-79,881,000	-2.90	0.00	0	5,377,000	3.95	-79,674,000	47,937,107	24,673,708	1,843,684	2,803,342	7.98	0.04	2.92	139,976,000	-49,872,752	-74,937,000	3.05	2.42	-64,600,000	0.00	0.00	0.00	0.00	3.42	0.03	0.00	-39.40	-73.75	0.00	0.00	0.00	2.53	94.44
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AGTC	Applied Genetic Technologies Corporation	110.49	2,355	4.72	8	1.9	-3.28	0.43	-11.78	-32.87	2.29	8.45	4.53	5.01		0.00	0.00	3.00	4.71	7.50	126,341,400	242,557	316,487	313,547	-2.16	-2.09	-2.19	-2.26	0.67	0.00	0.94	-0.17	5.12	5.27	70,954,824	-48,620,000	-1.46	28.93	2,453,000	14,795,000	26.33	-49,695,000	25,889,625	21,524,893	1,068,549	1,148,569	2.94	0.04	2.57	66,557,000	-25,291,000	-43,822,000	2.17	2.17	-13,933,000	-2,038.89	0.00	0.00	0.00	3.12	0.17	0.00	-36.72	-80.04	0.00	0.11	0.00	1.02	68.32
HEALTH CARE	Biotechnology	Biotechnology	AMEX	AIM	AIM ImmunoTech Inc.	105.63	2,434	2.15	3	2.0	-1.38	2.38	4.88	98.11	0.78	7.11	1.94	2.28		0.00	0.00	2.01	2.39	5.00	88,696,530	1,769,615	2,462,874	3,673,639	-5.87	-1.00	-0.37	-2.10	0.00	0.00	-1.32	1.03	49.89	50.01	48,882,612	-12,288,000	-3.98	285.86	171,000	2,348,000	3.84	-11,658,000	40,686,482	40,229,573	2,605,853	2,315,925	0.80	0.06	0.97	39,640,000	-7,620,750	-9,803,000	2.14	1.00	-753,000	-7,608.77	0.00	0.00	0.00	1.78	0.41	0.00	-18.77	-31.11	-41.00	0.01	0.00	1.47	6.68
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AKBA	Akebia Therapeutics Inc.	254.17	777	3.76	6	2.1	1.35	19.75	55.37	-51.36	2.09	13.71	3.03	7.01		0.00	0.00	3.00	7.00	10.00	536,239,299	7,869,317	5,629,946	4,664,848	-2.96	-0.98	-1.27	-3.84	0.02	0.00	1.36	0.23	1.62	2.16	372,403,296	-156,736,992	-2.38	1.21	308,163,008	105,419,000	33.15	-390,940,000	144,538,894	135,730,694	28,675,599	23,543,896	5.22	0.23	1.86	269,255,008	-77,117,504	-171,740,992	2.22	1.70	26,523,000	-62.40	-50.86	-126.86	15.92	1.55	0.21	0.00	-16.34	-99.54	-34.80	2.33	0.00	1.09	78.78
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AKRO	Akero Therapeutics Inc.	283.97	630	30.01	7	1.7	-3.35	1.42	8.81	31.01	10.78	41.16	27.91	28.83		0.00	0.00	45.00	60.29	79.00	1,078,113,000	255,970	274,451	260,403	-2.18	-2.68	-13.79	-11.20	-0.60	0.00	1.31	0.73	24.29	24.81	787,984,256	0	0.00	0.00	0	1,741,000	0.61	-65,107,000	34,721,845	16,640,444	2,530,734	1,805,598	10.16	0.13	8.41	291,870,016	-35,794,000	-59,058,000	8.25	3.64	0	0.00	0.00	0.00	0.00	3.46	0.12	0.00	-18.49	-30.29	0.00	0.00	0.00	8.40	93.80
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALBO	Albireo Pharma Inc.	550.15	107	37.73	7	1.5	3.71	5.36	16.38	50.86	11.26	49.00	37.62	30.77		0.00	0.00	65.00	70.71	79.00	694,030,300	205,257	233,467	231,302	-6.28	-8.41	-6.01	-4.17	-0.18	0.00	1.16	0.97	13.13	13.52	404,210,272	-84,563,000	-4.78	33.62	12,023,000	14,053,000	6.64	-90,356,000	19,077,247	15,851,094	1,772,461	714,791	5.91	0.10	14.61	278,691,008	-40,870,376	-85,234,000	11.10	3.40	9,636,000	-704.65	0.00	0.00	100.00	3.47	0.26	0.00	-21.94	-57.66	53.90	0.84	0.00	4.90	92.20
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALDX	Aldeyra Therapeutics Inc.	238.84	879	11.68	10	1.5	-3.39	-11.65	75.64	110.09	1.48	14.62	8.15	6.23		0.00	0.00	15.00	26.60	34.00	549,778,400	760,580	943,989	934,170	-1.26	-1.17	-9.25	-10.50	1.26	0.00	1.66	1.17	11.02	13.65	420,938,016	-37,720,056	-11.16	0.00	0	15,011,448	21.70	-39,422,172	45,662,453	32,070,653	2,215,488	1,549,191	4.17	0.07	1.83	71,175,504	-14,980,937	-40,402,580	1.79	6.52	0	0.00	0.00	0.00	0.00	3.79	0.41	0.00	-28.63	-65.68	0.00	0.00	0.00	2.28	67.35
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALEC	Alector Inc.	393.19	299	17.50	8	1.6	-3.58	-2.40	75.35	-35.52	9.12	35.93	14.89	18.34		0.00	0.00	28.00	32.13	41.00	1,438,255,000	383,041	588,632	745,972	-2.25	-2.87	-7.78	-5.78	-0.28	0.00	1.21	-0.01	6.51	6.61	898,915,520	-167,855,008	-5.36	40.41	22,246,000	45,993,000	14.83	-168,576,000	79,242,709	56,284,511	6,958,265	8,610,031	10.56	0.15	5.83	461,713,984	-73,144,000	-147,903,008	3.91	4.47	-79,309,000	-780.37	0.00	0.00	0.00	3.46	0.14	0.00	-22.11	-63.76	119.00	0.30	0.00	12.81	78.94
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALKS	Alkermes plc	153.51	1,677	21.69	11	3.0	-5.16	-5.08	33.07	21.79	11.98	23.02	20.22	17.97		0.00	0.00	15.00	21.36	28.00	3,639,756,000	930,104	1,306,188	1,381,591	-0.46	0.50	-46.75	43.38	0.23	0.00	0.75	0.71	2.25	2.71	3,455,971,584	3,806,000	908.03	2.95	1,171,490,944	385,598,016	35.56	-73,573,000	159,149,785	157,493,036	11,511,195	11,477,674	9.01	0.10	3.58	569,382,016	3,003,375	57,569,000	6.82	3.18	990,562,000	-6.68	0.33	-6.28	84.48	5.27	0.13	0.00	-2.69	-6.84	3.80	7.39	0.00	0.93	1.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALLK	Allakos Inc.	64.61	3,276	128.08	7	2.1	-2.59	0.82	31.27	79.80	41.61	157.96	121.13	88.89		0.00	0.00	36.00	122.00	204.00	6,903,665,000	297,414	299,814	268,452	-2.74	-3.76	-46.69	-35.19	-1.26	0.00	0.80	1.13	22.16	22.43	6,536,236,032	-138,008,992	-47.36	0.00	0	8,223,000	1.99	-133,817,000	52,503,346	33,887,760	4,170,776	4,579,361	13.46	0.19	8.00	419,755,008	-52,022,248	-98,620,000	8.45	15.16	0	0.00	0.00	0.00	0.00	2.89	0.30	0.00	-17.88	-28.83	0.00	0.00	0.00	10.03	96.94
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALLO	Allogene Therapeutics Inc.	182.57	1,330	34.17	13	1.7	3.61	8.13	1.13	46.12	17.43	55.00	29.59	35.55		0.00	0.00	31.00	49.69	70.00	4,626,439,000	1,115,242	902,714	897,935	-2.13	-2.45	-16.07	-13.95	-1.05	0.00	0.94	0.92	16.84	17.04	3,839,136,512	-246,158,000	-15.60	0.00	0	53,719,000	4.80	-242,680,992	140,280,152	71,662,116	13,037,704	10,648,858	12.98	0.16	6.00	841,022,016	-141,388,000	-155,384,992	8.01	4.27	0	0.00	0.00	0.00	0.00	3.41	0.21	0.00	-16.52	-27.92	0.00	0.00	0.00	35.74	61.50
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALNA	Allena Pharmaceuticals Inc.	6.29	4,078	2.17	5	1.8	28.40	38.22	64.39	-18.05	0.53	3.39	1.40	1.51		0.00	0.00	1.00	1.85	3.18	81,996,980	46,188,292	2,151,153	1,431,211	-1.22	-0.80	-1.78	-2.10	0.05	0.00	1.16	0.65	7.69	7.99	44,229,796	-32,524,000	-1.36	0.00	0	10,037,000	55.21	-33,946,000	50,250,950	29,216,378	1,498,804	1,191,322	1.05	0.03	0.79	30,136,000	-18,759,250	-32,254,000	0.48	4.55	0	0.00	0.00	0.00	0.00	28.38	0.14	0.00	-54.68	-156.54	0.00	0.00	0.00	3.88	42.24
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALNY	Alnylam Pharmaceuticals Inc.	198.31	1,161	170.02	23	2.0	-3.23	0.96	31.75	0.00	84.97	176.78	139.56	139.43		0.00	0.00	90.00	166.00	225.00	20,411,800,000	539,596	643,817	655,394	-7.83	-5.75	-21.73	-29.98	0.82	0.00	0.62	1.03	5.03	5.32	18,522,818,560	-902,460,992	-20.53	46.20	400,972,000	329,454,016	27.12	-890,926,016	116,180,768	115,202,526	3,490,047	3,781,758	7.45	0.04	15.79	1,833,875,968	-886,323,520	-687,796,992	10.46	16.25	194,688,000	-232.51	-225.07	-222.19	83.24	3.41	0.19	0.00	-19.92	-63.14	79.60	3.52	0.00	0.81	94.62
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALPN	Alpine Immune Sciences Inc.	388.51	311	11.55	5	1.5	-9.13	-11.90	52.58	287.58	2.05	16.37	11.84	8.38		0.00	0.00	18.00	21.40	27.00	302,538,500	171,021	117,134	311,038	-1.42	-0.80	-8.13	-14.44	0.19	0.00	-0.14	1.41	3.94	3.98	183,728,448	-28,762,000	-6.39	40.15	4,576,000	22,265,000	33.00	-27,738,000	23,803,183	8,782,184	52,738	26,922	0.37	0.01	5.93	141,075,008	9,991,250	33,762,000	2.83	4.08	-34,107,000	-640.41	0.00	0.00	0.00	10.31	1.22	0.00	-16.74	-54.23	561.90	0.23	0.00	28.49	52.56
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALRN	Aileron Therapeutics Inc.	94.14	2,697	2.02	3	1.5	-9.01	3.06	72.65	0.00	0.25	2.47	1.27	1.16		0.00	0.00	2.00	4.00	5.00	185,614,500	4,282,191	3,485,145	1,618,809	-0.74	-0.46	-2.73	-4.30	0.07	0.00	0.93	1.39	2.69	3.04	71,526,608	-23,425,000	-3.05	0.00	0	5,092,000	40.87	-23,396,000	83,610,151	21,295,159	1,556,658	1,264,936	1.39	0.04	0.35	14,121,000	-13,796,125	-22,092,000	0.31	6.47	-17,663,000	0.00	0.00	0.00	0.00	9.72	0.75	0.00	-52.62	-132.65	0.00	0.00	0.00	31.56	14.43
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALT	Altimmune Inc.	785.79	37	16.16	5	1.8	-4.38	18.91	38.71	675.68	1.60	35.10	12.26	12.89		0.00	0.00	24.00	25.46	41.40	558,900,300	2,969,988	1,831,491	2,788,742	-2.09	-1.06	-7.72	-15.94	0.16	0.00	-0.36	1.97	34.45	34.66	267,169,824	-25,071,692	-10.66	41.43	6,448,122	1,888,604	0.95	-42,519,324	33,071,020	23,235,182	2,926,944	2,181,265	1.35	0.09	6.29	206,777,984	-18,694,596	-23,025,308	6.07	2.66	-11,284,062	-393.31	0.00	0.00	-220.97	7.44	3.07	0.00	-10.96	-34.14	356.20	0.32	0.00	6.51	67.30
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ALXN	Alexion Pharmaceuticals Inc.	332.10	456	161.75	17	2.7	0.27	1.92	38.22	51.69	72.67	161.75	142.40	118.43		0.00	0.00	140.00	173.65	200.00	35,284,000,000	2,360,631	2,857,020	2,258,512	4.27	12.95	37.88	12.33	1.61	0.00	0.70	1.11	2.81	3.81	35,629,879,296	3,104,499,968	11.48	6.08	5,862,400,000	2,970,599,936	26.82	956,600,000	218,720,567	218,059,777	3,677,476	4,257,032	1.04	0.02	10.50	2,296,900,096	1,790,550,016	2,679,500,032	50.57	3.20	4,596,600,000	47.42	52.96	16.32	91.21	0.21	0.21	26.00	10.74	8.92	25.80	26.57	0.00	0.28	93.36
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AMGN	Amgen Inc.	289.48	607	258.60	25	2.3	0.58	4.16	17.51	14.35	177.05	264.97	232.17	236.98	2021-02-11	7.04	2.74	185.00	255.64	304.00	149,675,500,000	2,009,070	2,420,435	2,632,599	12.40	17.00	20.85	15.21	7.72	0.00	0.79	0.58	1.66	2.28	171,602,542,592	12,647,000,064	13.57	6.87	24,987,000,832	34,286,999,552	312.87	7,352,000,000	582,168,612	581,126,530	6,958,047	6,512,093	2.82	0.01	21.23	12,359,999,488	9,219,999,744	10,858,000,384	18.78	13.77	19,006,000,000	37.57	50.61	29.42	76.73	0.52	0.07	4.90	9.45	67.18	12.00	42.41	0.00	0.19	77.99
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AMRN	Amarin Corporation plc	192.77	1,212	7.48	11	2.2	-1.06	18.92	49.30	0.00	3.36	20.41	5.22	5.93		0.00	0.00	5.00	10.00	19.00	2,939,550,000	10,044,663	8,349,591	8,210,113	-0.04	-0.03	-170.00	-218.33	5.34	0.00	1.10	-0.11	2.17	2.72	2,010,435,584	-19,474,000	-103.24	3.41	590,086,016	20,031,000	3.30	-15,858,000	391,214,481	348,993,831	22,057,014	23,705,489	2.64	0.00	1.45	561,862,016	14,148,500	7,641,000	1.55	4.83	333,736,000	-3.61	-3.30	-2.69	78.42	0.81	0.25	0.00	-1.46	-2.64	39.20	1.58	0.00	1.03	39.44
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ANAB	AnaptysBio Inc.	121.34	2,154	24.42	6	2.5	-1.89	-5.09	-17.78	81.26	12.06	31.29	24.60	20.79		0.00	0.00	16.00	28.00	42.00	680,686,900	584,764	310,371	327,808	-2.71	-2.25	-9.00	-11.35	0.53	0.00	0.92	1.15	13.83	14.13	361,000,928	-78,927,000	-4.57	20.06	18,000,000	884,000	0.25	-73,840,000	27,347,805	17,849,639	3,526,232	3,757,358	15.45	0.20	12.37	338,345,984	-44,388,248	-67,540,000	13.17	1.85	-91,338,000	-441.57	0.00	0.00	0.00	2.18	0.30	0.00	-11.88	-18.91	0.00	0.66	0.00	0.77	1.06
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ANCN	Anchiano Therapeutics Ltd.	63.66	3,297	2.39	0	3.0	-1.65	14.35	95.90	77.70	0.51	5.49	1.91	1.31		0.00	0.00	0.00	0.00	0.00	90,151,430	98,190	2,115,269	710,535	-2.03	-0.62	-1.18	-3.85	0.02	0.00	1.21	1.05	2.98	3.25	11,498,284	-9,231,000	-1.25	0.00	0	236,000	4.41	-15,069,000	37,099,352	3,090,079	40,796	1,885	0.01	0.00	0.91	6,768,000	-17,542,376	-16,936,000	0.72	3.31	0	0.00	0.00	0.00	0.00	1.97	0.33	0.00	-30.87	-205.90	0.00	0.00	0.00	3.82	3.46
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ANIK	Anika Therapeutics Inc.	224.78	958	38.20	2	1.0	-1.27	-4.38	9.02	-12.37	22.01	47.48	40.06	36.33		0.00	0.00	43.00	52.00	61.00	549,959,600	77,651	106,307	124,285	-0.30	0.38	-125.66	102.53	0.56	0.00	0.99	0.07	4.75	6.48	477,189,536	21,865,000	21.82	3.74	127,541,000	48,150,000	16.93	-4,275,000	14,214,516	13,266,692	1,632,287	1,726,906	13.78	0.14	8.78	124,758,000	15,277,500	23,500,000	20.02	1.91	85,863,000	8.13	17.14	-3.35	63.35	1.21	0.06	0.00	1.76	-1.51	6.70	8.97	0.00	1.60	98.77
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ANIX	Anixa Biosciences Inc.	166.46	1,514	3.93	2	2.0	-7.09	-10.27	100.51	6.05	1.33	5.40	3.07	2.54		0.00	0.00	8.50	8.75	9.00	110,304,900	647,429	777,678	430,542	-0.45	-0.60	-8.71	-7.02	-0.26	0.00	0.94	0.45	7.62	7.88	100,284,560	-9,939,926	-10.09	0.00	0	55,198	0.67	-10,018,355	26,076,819	24,692,922	1,106,101	916,540	0.84	0.05	0.35	9,057,061	-2,432,536	-6,175,671	0.36	10.89	0	0.00	0.00	0.00	0.00	7.09	0.03	0.00	-79.21	-154.36	0.00	0.00	0.00	5.96	7.72
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APLS	Apellis Pharmaceuticals Inc.	175.80	1,411	44.89	14	1.8	-3.02	-14.48	34.12	13.15	16.85	58.47	50.12	36.46		0.00	0.00	31.00	62.64	104.00	3,505,862,000	829,649	737,616	758,006	-8.02	-6.51	-5.60	-7.02	0.30	0.00	1.00	0.52	9.67	9.86	3,104,385,792	-449,330,560	-6.91	4,805.55	646,000	372,880,992	352.31	-536,356,608	75,736,924	55,213,732	9,038,523	9,043,669	10.97	0.18	9.61	728,158,016	-215,711,728	-384,538,432	1.40	32.11	0	-69,626.51	0.00	0.00	100.00	3.07	0.06	0.00	-45.54	-437.13	0.00	0.01	0.00	21.17	82.85
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APLT	Applied Therapeutics Inc.	147.50	1,761	20.55	6	1.7	-1.06	-5.86	13.47	-60.79	13.58	57.39	21.36	28.62		0.00	0.00	27.06	35.00	53.00	467,077,500	69,151	137,459	179,194	-4.72	-4.61	-4.35	-4.28	1.80	0.00	1.33	-0.48	5.68	5.99	331,108,832	0	0.00	0.00	0	3,924,000	3.81	-87,905,000	22,488,081	11,729,558	1,551,642	1,477,262	11.64	0.11	5.18	116,505,000	-38,961,876	-67,866,000	4.58	4.48	0	0.00	0.00	0.00	0.00	0.83	0.24	0.00	-68.16	-131.51	0.00	0.00	0.00	23.88	71.47
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APM	Aptorum Group Limited	202.25	1,135	3.44	2	2.0	0.88	8.18	60.75	-77.05	1.16	18.25	2.67	2.91		0.00	0.00	3.50	4.14	4.77	115,981,000	339,024	689,788	744,506	-0.54	-0.60	-6.42	-5.77	-0.54	0.00	0.62	0.32	1.50	1.99	100,161,808	-16,862,956	-5.94	160.87	622,647	3,174,111	18.12	-15,802,856	11,574,270	7,432,174	42,542	201,231	0.16	0.01	0.14	4,322,373	-6,909,744	-13,073,569	0.65	5.27	-259,379	-2,935.77	0.00	0.00	-38.04	1.18	0.31	0.00	-47.55	-84.08	36.50	0.02	0.00	26.43	0.77
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APRE	Aprea Therapeutics Inc.	100.80	2,558	5.64	5	2.8	-1.05	4.44	-74.11	-84.91	4.66	41.12	17.42	26.18		0.00	0.00	5.00	7.40	10.00	120,764,900	1,711,272	1,329,413	428,400	-26.67	-1.99	-0.21	-2.87	0.00	0.00	0.74	-0.76	7.39	7.49	20,207,232	-50,553,120	-0.40	0.00	0	377,083	0.42	-51,159,004	21,186,827	10,030,268	1,761,322	958,760	1.23	0.30	4.77	101,146,632	-19,807,552	-43,346,044	-59.91	-0.09	0	0.00	0.00	0.00	0.00	0.72	0.34	0.00	-39.46	-75.00	0.00	0.00	0.00	12.91	87.80
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APTO	Aptose Biosciences Inc.	47.49	3,608	4.26	1	2.0	-3.18	-4.70	-7.99	-27.15	3.92	9.25	4.91	5.85		0.00	0.00	4.72	4.72	4.72	390,056,600	892,659	1,686,851	1,099,381	-0.65	-0.54	-6.56	-7.87	0.39	0.00	0.92	-0.01	24.38	24.60	259,462,640	-48,741,000	-5.32	0.00	0	1,195,000	0.93	-48,234,000	88,861,737	64,674,461	4,523,603	3,148,521	1.79	0.05	1.49	132,724,000	-11,755,125	-29,771,000	1.45	2.93	0	0.00	0.00	0.00	0.00	3.08	0.11	0.00	-36.44	-61.61	0.00	0.00	0.00	5.09	52.64
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APTX	Aptinyx Inc.	112.99	2,304	3.87	7	1.8	-0.77	-10.62	29.00	-11.11	1.60	6.47	3.62	3.64		0.00	0.00	3.82	8.00	10.71	246,701,100	556,586	774,485	785,876	-1.23	-1.11	-3.15	-3.60	0.32	0.00	0.68	0.23	24.39	26.50	149,216,752	-52,991,000	-2.82	60.12	2,482,000	0	0.00	-52,343,000	63,256,689	37,100,681	1,919,732	1,208,740	2.64	0.04	1.64	103,810,000	-31,785,250	-49,903,000	2.33	1.66	-40,661,000	-2,152.18	0.00	0.00	0.00	0.71	0.06	0.00	-28.47	-47.01	-72.50	0.06	0.00	3.35	55.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	APVO	Aptevo Therapeutics Inc.	319.88	494	36.57	3	1.7	5.36	16.02	225.65	280.99	2.94	60.00	39.38	15.82		0.00	0.00	64.00	65.67	69.00	143,873,300	153,881	163,195	794,021	-5.84	-5.29	-6.27	-6.34	0.67	0.00	0.94	1.57	3.56	4.13	142,451,120	-28,648,000	-4.97	4.15	34,360,000	28,328,000	1,286.47	-34,784,000	4,378,759	1,349,864	152,967	276,692	1.44	0.04	6.02	24,942,000	-12,276,125	-28,295,000	0.68	53.70	-17,260,000	-88.02	-83.38	-54.92	-23.02	4.11	1.26	0.00	-38.59	-316.98	0.00	10.62	0.00	5.93	75.18
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARAV	Aravive Inc.	62.46	3,324	5.90	3	1.7	-0.84	-1.99	19.68	-45.44	3.34	14.94	5.87	8.01		0.00	0.00	5.73	6.79	8.28	95,719,230	93,022	163,836	188,232	-2.07	-2.06	-2.85	-2.89	4.54	0.00	1.22	-0.15	11.07	11.37	47,746,144	-24,487,000	-1.95	0.00	0	8,407,000	17.03	-30,825,000	16,087,266	9,858,598	652,368	711,538	3.11	0.05	3.36	53,967,000	-11,238,250	-21,465,000	3.07	1.92	-8,083,000	0.00	0.00	0.00	0.00	0.66	0.18	0.00	-26.36	-63.63	0.00	0.00	0.00	30.17	41.00
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARCT	Arcturus Therapeutics Holdings Inc.	149.60	1,731	64.99	13	2.3	-6.41	-5.06	16.18	509.66	8.51	129.71	76.17	52.97		0.00	0.00	31.00	91.54	152.00	1,819,285,000	840,431	2,136,984	1,141,310	-2.94	-1.32	-22.12	-49.23	0.40	0.00	0.43	2.00	11.05	11.21	1,305,211,520	-52,893,000	-24.68	127.10	10,269,000	20,429,000	7.81	-52,033,000	25,858,084	18,431,291	3,168,391	4,587,838	1.23	0.17	12.54	307,023,008	-25,857,876	-43,767,000	10.69	6.08	-12,851,000	-522.53	0.00	0.00	0.00	8.34	1.95	0.00	-16.37	-34.98	-29.70	0.58	0.00	18.43	70.46
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARDS	Aridis Pharmaceuticals Inc.	242.22	862	7.12	5	2.0	1.57	0.14	9.37	1.47	3.80	10.18	6.76	6.97		0.00	0.00	7.00	11.00	17.20	70,560,750	15,192	14,599	11,340	-2.48	-3.47	-2.87	-1.99	-0.07	0.00	0.20	0.50	0.35	0.56	63,855,860	-21,930,000	-2.91	63.86	1,000,000	715,000	0.00	-22,158,000	10,065,727	6,338,288	4,982	8,248	0.30	0.00	0.62	6,212,000	7,333,125	-11,711,000	-1.27	-5.62	-23,061,000	-2,226.70	0.00	0.00	0.00	1.55	0.03	0.00	-59.89	0.00	0.00	0.11	0.00	37.03	1.84
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARDX	Ardelyx Inc.	241.01	869	7.36	6	1.4	-4.29	7.76	37.31	-1.37	4.22	8.81	6.53	6.37		0.00	0.00	11.00	13.67	15.00	694,010,700	589,376	709,743	634,566	-1.01	-1.20	-7.28	-6.02	-0.39	0.00	0.97	0.34	11.26	11.72	519,547,904	-80,078,000	-6.49	64.85	8,012,000	53,451,000	40.70	-85,227,000	90,248,465	58,543,277	4,782,840	5,834,635	5.65	0.07	2.06	185,496,992	-43,339,000	-74,982,000	1.46	5.06	4,681,000	-1,023.28	0.00	0.00	235.37	4.29	0.02	0.00	-32.23	-94.44	-10.00	0.10	0.00	1.19	86.37
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARGX	argenx SE	55.29	3,458	300.99	15	2.1	-4.55	4.88	16.91	103.11	103.75	317.02	287.14	239.40		0.00	0.00	240.79	305.47	376.23	0	163,080	155,575	177,323	-1.73	-14.08	-174.49	-21.38	-0.24	0.00	0.75	1.59	0.00	0.00	14,854,722,560	0	0.00	0.00	0	0	0.43	0	47,341,929	47,027,472	1,102,538	1,167,381	7.32	0.00	0.00	0	0	0	11.95	25.18	-115,081,000	0.00	0.00	0.00	0.00	4.98	0.45	0.00	0.00	0.00	16.10	0.00	0.00	0.00	54.78
HEALTH CARE	Biotechnology	Biotechnology	AMEX	ARMP	Armata Pharmaceuticals Inc.	248.59	824	3.64	4	1.7	4.00	4.90	11.32	2.54	2.52	6.92	3.16	3.39		0.00	0.00	5.00	7.25	9.00	65,456,590	73,621	29,698	20,651	-1.42	-0.87	-2.56	-4.18	0.07	0.00	0.24	0.70	2.29	2.41	62,606,592	-17,705,000	-3.54	196.26	319,000	13,035,000	52.95	-20,143,000	18,701,883	8,163,933	110,793	16,998	3.23	0.02	0.85	15,885,000	-6,531,375	-14,697,000	1.32	2.76	0	-5,908.15	0.00	0.00	0.00	3.88	0.14	0.00	-31.42	-94.23	0.00	0.02	0.00	63.12	15.98
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARNA	Arena Pharmaceuticals Inc.	164.46	1,538	76.25	14	1.6	-2.24	-5.51	-8.45	0.00	32.95	90.19	72.18	67.27		0.00	0.00	76.00	94.79	116.00	4,536,794,000	430,575	558,991	671,902	-7.04	-7.64	-10.84	-10.17	-1.26	0.00	0.78	1.27	22.50	23.17	3,408,286,208	-381,428,000	-8.94	1,037.85	3,284,000	57,969,000	4.96	-370,884,000	58,164,022	54,937,664	3,808,054	3,533,066	6.55	0.07	20.08	1,167,864,064	-185,531,872	-308,139,008	20.16	3.78	574,935,000	-11,729.93	0.00	0.00	0.00	2.54	0.30	0.00	-19.13	-32.03	-98.50	0.06	0.00	0.19	91.89
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ARWR	Arrowhead Pharmaceuticals Inc.	146.91	1,773	81.14	13	2.1	-3.55	-1.23	36.44	86.48	19.51	86.75	74.38	50.78		0.00	0.00	34.00	83.23	100.00	8,644,927,000	677,780	1,009,881	1,241,143	-0.84	-0.92	-96.60	-91.45	-10.14	0.00	1.08	1.14	7.78	7.92	8,138,893,824	-87,216,536	-93.32	92.50	87,992,064	21,137,956	4.58	-84,553,224	102,756,771	99,619,607	5,889,119	7,827,282	5.86	0.08	3.07	315,492,128	-78,670,192	-95,391,568	4.51	17.99	87,992,066	-105.87	-99.12	-96.09	100.00	3.89	0.35	0.00	-13.35	-23.96	-82.40	0.87	0.00	2.60	67.06
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ASLN	ASLAN Pharmaceuticals Limited	28.04	3,917	2.50	0	2.3	20.77	21.95	61.29	-4.17	0.83	2.50	1.93	1.79		0.00	0.00	0.00	0.00	0.00	66,343,059	3,082,484	444,149	241,079	-1.17	-0.68	-2.14	-3.68	0.05	0.00	0.54	0.61	2.03	2.09	85,733,144	-17,936,472	-4.78	451.92	189,710	18,661,924	0.00	-43,116,720	189,954,970	37,990,240	13,216	24,253	0.02	0.00	0.32	12,060,285	0	0	-0.32	-7.76	79,821,000	-9,481.98	0.00	0.00	95.78	20.70	0.15	0.00	-49.35	-6,043.74	0.00	0.01	0.00	0.00	10.72
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ASMB	Assembly Biosciences Inc.	158.40	1,616	5.94	5	1.7	-1.82	-2.94	-60.08	-66.27	4.78	27.84	5.95	15.90		0.00	0.00	7.00	5.92	4.50	199,785,100	846,758	1,003,471	588,447	-1.49	-3.51	-3.99	-1.69	-0.03	0.00	1.25	-0.27	14.37	14.66	-27,382,868	-51,624,000	0.53	-0.33	82,834,000	10,773,000	3.98	-49,818,000	33,022,336	24,783,924	2,726,639	2,992,090	2.89	0.09	7.21	237,940,992	-12,834,750	-58,216,000	8.22	0.72	-69,794,000	-62.92	-62.32	-60.14	-15.81	1.56	0.26	0.00	-12.30	-23.33	718.00	2.48	0.00	4.65	94.26
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ASND	Ascendis Pharma A/S	144.54	1,805	155.72	12	1.5	-2.00	-1.62	-6.45	18.11	92.00	183.98	166.77	151.10		0.00	0.00	167.83	192.79	217.07	8,466,371,999	329,395	172,051	197,366	-3.87	-7.56	-40.23	-21.25	-0.42	0.00	0.55	0.54	14.56	14.80	8,272,015,872	0	0.00	0.00	0	0	3.50	0	52,844,991	35,087,428	2,217,475	2,168,194	13.12	0.00	0.00	0	0	0	8.43	18.47	13,375,000	0.00	0.00	0.00	100.00	2.05	0.07	0.00	-21.04	-44.69	22.90	0.00	0.00	0.03	1.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ATHX	Athersys Inc.	78.55	3,004	2.08	5	1.7	-3.26	11.23	10.05	48.57	1.13	4.38	1.86	2.28		0.00	0.00	5.00	2.16	2.86	425,053,900	3,855,063	2,499,131	3,104,093	-0.38	-0.41	-5.55	-5.07	-0.59	0.00	0.21	0.94	3.20	3.32	363,506,912	-65,564,000	-5.54	795.42	457,000	164,000	0.37	-66,482,000	197,699,500	178,868,623	26,114,566	32,106,684	10.02	0.15	0.31	61,711,000	-30,372,376	-54,688,000	0.22	9.29	-33,412,000	-14,529.32	0.00	0.00	0.00	3.47	0.22	0.00	-71.37	-186.84	0.00	0.00	0.00	9.54	28.58
HEALTH CARE	Biotechnology	Biotechnology	AMEX	ATNM	Actinium Pharmaceuticals Inc. (Delaware)	117.93	2,209	8.22	4	1.8	-2.26	-2.49	-19.73	18.58	4.71	19.47	10.11	9.86		0.00	0.00	6.50	7.96	12.33	114,262,700	510,729	561,896	6,277,128	-2.14	-1.42	-3.83	-5.89	0.11	0.00	0.49	0.66	10.31	10.51	66,226,348	-20,160,358	-3.29	0.00	0	877,000	1.93	-20,438,324	13,586,525	12,777,583	1,060,345	790,322	1.60	0.08	3.55	48,234,000	-12,873,242	-20,369,448	3.34	2.46	0	0.00	0.00	0.00	0.00	2.33	0.08	0.00	-38.51	-73.83	0.00	0.00	0.00	1.55	22.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ATNX	Athenex Inc.	172.08	1,449	13.94	9	1.7	4.11	24.02	16.56	-10.81	5.63	15.67	12.25	11.77		0.00	0.00	12.10	16.67	27.41	1,249,813,000	1,405,496	809,463	700,875	-1.46	-1.20	-9.58	-10.32	0.55	0.00	1.36	0.41	4.22	4.87	1,046,454,784	-94,445,000	-11.08	6.67	156,944,000	132,748,000	62.55	-118,413,000	93,339,242	61,869,917	6,939,595	6,622,884	7.45	0.09	2.45	228,310,000	-72,698,248	-120,428,000	2.42	5.76	-49,362,000	-62.86	-60.18	-75.45	-10.72	4.11	0.02	0.00	-17.69	-69.41	83.20	1.93	0.00	19.52	58.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ATOS	Atossa Therapeutics Inc.	120.58	2,171	2.61	2	2.0	-12.42	85.11	65.19	21.43	0.76	5.08	1.30	2.33		0.00	0.00	1.99	2.39	5.00	212,768,500	152,493,726	15,544,950	4,408,115	-1.38	-0.80	-1.89	-2.34	0.05	0.00	1.03	1.02	6.10	7.23	11,169,931	-12,948,696	-0.86	0.00	0	31,280	0.32	-12,962,660	47,548,835	7,299,865	663,310	444,647	0.08	0.02	0.87	9,105,950	-6,020,996	-10,846,102	0.88	2.95	0	0.00	0.00	0.00	0.00	12.69	0.32	0.00	-57.96	-104.16	0.00	0.00	0.00	0.12	6.49
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ATRA	Atara Biotherapeutics Inc.	115.83	2,247	19.56	9	2.2	1.24	2.84	48.86	35.09	4.52	28.20	21.37	14.71		0.00	0.00	9.00	24.83	32.89	1,590,465,000	1,100,501	1,021,362	1,137,491	-4.53	-3.63	-4.32	-5.08	0.22	0.00	1.20	0.85	9.10	9.41	1,118,995,712	-298,907,008	-3.74	0.00	0	13,129,000	3.71	-303,808,992	82,816,343	50,464,559	11,992,298	12,343,918	10.83	0.17	4.21	327,184,992	-133,398,752	-235,328,992	4.58	4.27	0	0.00	0.00	0.00	0.00	1.07	0.18	0.00	-49.83	-90.37	0.00	0.00	0.00	0.93	1.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AUPH	Aurinia Pharmaceuticals Inc	81.69	2,929	17.62	7	1.7	-5.93	29.27	26.13	-3.98	9.83	20.50	14.23	14.98		0.00	0.00	9.00	11.50	14.00	0	12,340,667	3,470,987	1,834,811	-1.41	-0.55	-12.52	-32.04	0.21	0.00	0.64	0.25	16.46	17.23	1,986,874,624	-108,300,000	-18.35	16,981.84	117,000	8,298,000	2.08	-156,604,000	126,568,000	111,116,579	5,122,196	5,499,485	2.24	0.00	3.10	392,041,984	-60,657,500	-100,594,000	3.15	5.59	-52,548,000	-93,735.90	0.00	0.00	0.00	5.91	0.04	0.00	-22.38	-59.93	-87.40	0.00	0.00	9.78	55.87
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AUTL	Autolus Therapeutics plc	146.02	1,787	8.80	9	2.0	-1.12	-3.40	-22.54	-13.85	3.00	17.19	9.48	12.04		0.00	0.00	10.00	15.92	20.78	465,460,000	153,342	200,704	160,864	-1.40	-2.65	-6.29	-3.31	-0.07	0.00	1.10	0.23	10.32	11.05	127,795,384	-68,942,608	-1.85	118.49	1,078,500	0	0.00	-53,279,500	52,234,928	33,904,120	705,920	796,003	3.78	0.00	5.52	217,450,000	0	0	5.91	1.49	-102,510,000	-6,570.75	0.00	0.00	0.00	1.07	0.06	0.00	-22.28	-29.62	0.00	0.03	0.00	31.86	25.44
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AVEO	AVEO Pharmaceuticals Inc.	309.27	526	8.17	4	1.2	-1.45	-4.44	43.84	39.83	2.23	10.71	6.21	5.89		0.00	0.00	9.00	12.00	17.00	238,828,700	302,582	412,409	564,594	-1.52	-1.67	-5.38	-5.02	-0.54	0.00	1.02	0.78	4.19	4.29	187,297,600	0	0.00	31.76	5,897,000	14,432,000	35.88	-28,541,000	28,809,249	24,775,090	791,826	1,108,981	2.67	0.03	2.39	68,844,000	-15,460,625	-32,474,000	1.56	5.24	10,837,000	-556.47	0.00	0.00	-283.53	1.59	0.15	0.00	-30.89	-96.78	-86.00	0.31	0.00	0.14	34.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AVRO	AVROBIO Inc.	56.90	3,432	14.44	7	1.9	-3.15	-1.03	-6.90	-32.65	9.76	29.32	14.52	16.23		0.00	0.00	18.00	36.71	18.46	618,006,900	179,156	368,019	285,117	-3.31	-3.37	-4.36	-4.28	-2.58	0.00	1.29	0.17	8.86	9.14	323,917,664	-114,454,000	-2.83	0.00	0	0	0.00	-114,243,000	41,450,950	29,556,987	3,546,679	2,968,163	9.42	0.10	6.02	219,546,000	-46,509,124	-86,898,000	5.70	2.53	0	0.00	0.00	0.00	0.00	3.05	0.12	0.00	-32.08	-55.11	0.00	0.00	0.00	2.40	92.09
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AVXL	Anavex Life Sciences Corp.	270.47	692	6.09	5	1.7	-3.03	1.84	0.33	105.05	2.20	7.69	5.49	4.61		0.00	0.00	10.00	13.00	17.00	420,527,400	460,338	1,110,858	953,974	-0.45	-0.52	-13.47	-11.71	-0.90	0.00	0.91	1.27	4.67	4.73	378,555,392	0	0.00	0.00	0	0	0.00	-26,280,470	66,962,957	64,615,236	5,620,201	7,427,616	3.62	0.09	0.44	29,249,018	-11,702,330	-21,287,046	0.44	13.87	0	0.00	0.00	0.00	0.00	3.45	0.44	0.00	-55.77	-110.59	0.00	0.00	0.00	3.63	19.19
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AXLA	Axcella Health Inc.	122.23	2,137	5.78	9	1.8	-1.20	1.23	24.84	14.31	2.25	7.73	5.50	5.09		0.00	0.00	8.00	8.91	16.11	219,614,200	57,401	96,862	208,898	-2.03	-1.89	-2.85	-3.17	0.43	0.00	1.02	0.59	22.20	22.66	132,729,904	-54,222,000	-2.45	0.00	0	25,115,000	28.30	-57,051,000	37,540,886	15,696,595	336,774	278,432	3.62	0.02	3.12	117,255,000	-33,391,876	-53,089,000	2.37	2.44	0	0.00	0.00	0.00	0.00	1.24	0.05	0.00	-29.82	-69.96	0.00	0.00	0.00	17.28	67.19
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	AZRX	AzurRx BioPharma Inc.	45.96	3,633	1.99	3	2.2	-8.30	118.68	184.29	95.10	0.37	2.63	0.89	0.84		0.00	0.00	2.00	4.00	2.23	84,304,370	14,440,192	7,654,053	2,143,128	-0.90	-0.43	-2.21	-4.63	0.04	0.00	0.61	1.12	4.34	4.40	54,731,200	-9,978,223	-5.49	0.00	0	105,625	0.75	-24,707,908	38,849,938	27,324,359	88,405	172,871	0.20	0.00	0.37	11,368,680	-3,291,448	-8,557,542	0.49	4.09	0	0.00	0.00	0.00	0.00	8.67	0.41	0.00	-48.55	-191.73	0.00	0.00	0.00	11.09	5.14
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BBIO	BridgeBio Pharma Inc.	122.92	2,127	62.33	8	1.7	-5.26	-10.16	56.29	99.66	14.23	71.84	59.29	39.55		0.00	0.00	44.00	63.75	91.00	8,073,461,000	4,700,773	768,517	691,304	-4.73	-2.36	-13.18	-29.44	0.26	0.00	1.07	1.12	9.49	9.85	8,343,736,832	0	0.00	380.19	21,946,000	483,747,008	221.51	-402,200,992	122,702,569	43,820,589	10,750,649	10,978,609	16.25	0.21	5.80	710,681,024	-215,145,504	-379,656,000	3.92	15.91	38,060,000	-1,939.45	0.00	0.00	100.00	5.57	0.33	0.00	-37.25	-122.43	-69.60	0.19	0.00	8.89	1.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCDA	BioCardia Inc.	125.52	2,085	4.09	4	2.0	-3.99	-1.92	95.69	-13.94	1.91	8.60	3.34	2.97		0.00	0.00	4.10	6.05	7.00	61,632,100	213,291	4,767,161	1,288,914	-1.83	-0.96	-2.24	-4.26	0.05	0.00	-0.17	0.45	1.96	1.99	46,816,664	-15,481,000	-3.02	149.10	314,000	1,262,000	30.68	-15,516,000	16,257,104	6,687,561	597,098	11,265	0.06	0.06	0.60	7,392,000	-7,243,000	-12,196,000	0.33	12.36	-8,210,000	-4,957.33	0.00	0.00	0.00	3.91	0.10	0.00	-96.41	-333.43	-82.50	0.04	0.00	42.90	14.56
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCEL	Atreca Inc.	163.96	1,543	15.30	8	1.6	-1.10	-1.29	13.25	-20.03	10.88	29.35	15.45	15.87		0.00	0.00	25.00	29.75	35.00	463,964,900	203,066	172,539	226,524	-6.36	-2.60	-2.41	-5.80	0.04	0.00	1.33	0.27	27.99	28.48	294,705,280	-84,314,000	-3.50	0.00	0	65,000	0.03	-83,441,000	29,991,270	17,970,505	3,357,896	2,788,239	17.26	0.15	7.06	259,264,000	-43,528,248	-64,793,000	7.33	2.09	0	0.00	0.00	0.00	0.00	1.02	0.08	0.00	-22.19	-35.79	0.00	0.00	0.00	4.59	90.60
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCLI	Brainstorm Cell Therapeutics Inc.	141.05	1,855	6.65	2	3.0	14.85	25.71	-38.25	27.10	3.80	17.95	5.43	9.77		0.00	0.00	7.96	9.23	10.50	182,776,400	5,170,630	1,554,080	863,631	-1.02	-1.37	-6.53	-4.23	-0.19	0.00	0.66	1.16	4.71	4.72	140,000,240	-27,653,000	-5.06	0.00	0	1,500,000	5.77	-27,688,000	31,567,592	27,339,113	5,402,993	6,769,063	5.16	0.20	0.91	28,808,000	-21,065,124	-30,893,000	0.82	8.08	0	0.00	0.00	0.00	0.00	14.62	0.29	0.00	-85.98	-288.40	0.00	0.00	0.00	19.78	22.78
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCRX	BioCryst Pharmaceuticals Inc.	247.96	828	9.16	9	2.1	0.00	0.99	131.90	186.92	1.58	9.78	6.99	4.88		0.00	0.00	7.00	11.22	16.00	1,617,341,000	4,773,459	7,383,945	7,830,905	-0.80	-0.95	-11.44	-9.69	-0.61	0.00	1.23	1.53	1.33	1.45	1,563,625,344	-121,708,000	-12.85	29.22	53,521,000	80,775,000	240.14	-124,943,000	176,565,622	162,254,978	30,945,985	37,415,500	2.95	0.19	0.81	143,319,008	-63,878,000	-103,025,000	0.19	47.96	-62,334,000	-228.81	-227.40	-233.45	-121.50	0.73	0.73	0.00	-57.39	0.00	243.80	0.34	0.00	0.85	73.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BCYC	Bicycle Therapeutics plc	678.14	64	26.83	8	1.6	-0.56	-10.45	42.56	141.44	10.26	33.00	20.90	18.07		0.00	0.00	25.00	34.88	58.00	574,803,500	90,765	110,751	70,176	-4.99	-2.06	-5.38	-13.01	0.09	0.00	0.59	1.43	9.31	9.63	436,882,656	-38,446,000	-11.36	36.95	11,823,000	15,756,000	14.38	-37,983,000	21,304,801	6,454,503	332,793	298,232	6.61	0.00	7.03	149,842,000	-10,533,000	-6,091,000	5.33	5.04	-11,739,000	-335.48	0.00	0.00	-151.54	1.12	0.56	0.00	-17.33	-37.08	525.70	0.64	0.00	29.90	42.85
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BFRA	Biofrontera AG	111.37	2,338	7.84	2	2.0	-2.49	-4.51	22.31	-30.12	5.27	55.00	7.38	7.76		0.00	0.00	11.00	12.00	13.00	0	21,547	53,616	266,858	-0.76	-1.59	-10.29	-4.93	-0.09	0.00	0.52	0.64	2.16	2.69	175,809,504	0	0.00	0.00	0	0	0.00	0	47,747,515	11,843,372	1,693	4,766	0.05	0.00	0.00	0	0	0	0.68	11.56	26,390,000	0.00	-17.05	-50.96	90.17	2.37	0.12	0.00	-8.44	-255.71	-8.60	0.00	0.00	0.00	0.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BGNE	BeiGene Ltd.	234.90	895	358.34	16	2.2	-4.93	0.47	19.45	133.28	118.55	382.20	274.62	235.12		0.00	0.00	170.18	304.08	388.00	35,081,140,000	429,254	481,689	312,488	-19.92	-13.72	-17.99	-27.30	0.58	0.00	0.56	1.77	7.44	7.69	29,608,921,088	-1,529,362,048	-19.36	111.45	265,666,000	243,732,000	5.67	-1,512,221,952	1,185,464,217	47,071,639	2,161,429	2,461,419	3.28	0.00	51.86	4,718,770,176	-705,213,760	-1,218,307,968	47.12	7.60	-570,316,000	-587.51	0.00	0.00	0.00	5.41	0.51	0.00	-26.20	-54.22	81.60	3.50	0.00	20.59	66.29
HEALTH CARE	Biotechnology	Biotechnology	NYSE	BHVN	Biohaven Pharmaceutical Holding Company Ltd.	134.54	1,944	88.78	11	1.7	2.68	14.07	10.05	49.62	26.56	100.77	88.52	70.49		0.00	0.00	67.00	96.27	121.00	5,182,340,000	832,500	590,714	645,202	-12.30	-9.81	-7.22	-8.12	0.36	0.00	1.33	1.07	2.88	3.26	4,736,040,448	-604,872,000	-7.83	166.10	28,513,000	448,340,000	0.00	-698,323,968	59,939,166	52,081,141	5,327,995	6,341,945	12.09	0.12	9.11	546,214,016	-440,232,512	-591,088,000	-3.56	-24.96	0	-2,138.28	0.00	0.00	72.90	2.42	0.27	0.00	-62.41	0.00	0.00	0.50	0.00	13.79	1.18
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BIIB	Biogen Inc.	402.67	279	271.67	29	2.7	-1.41	-0.79	9.98	-4.16	223.25	374.99	251.46	277.24		0.00	0.00	175.00	291.38	450.00	42,400,540,000	777,252	1,285,677	1,530,790	30.21	24.91	8.99	10.82	-0.16	0.00	0.85	0.28	1.61	2.06	45,702,156,288	7,149,499,904	6.39	3.20	14,263,300,096	7,834,100,224	72.91	5,082,399,744	153,881,597	152,889,061	3,726,199	4,136,941	2.96	0.02	23.26	3,579,800,064	4,682,087,424	6,557,100,032	69.91	3.89	12,422,500,000	46.90	50.13	35.63	87.65	1.39	0.02	-46.80	15.95	41.58	-6.20	85.45	0.00	0.63	87.89
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BIOC	Biocept Inc.	221.76	985	6.33	1	2.0	-3.36	1.61	42.25	0.00	2.10	13.00	5.09	5.53		0.00	0.00	6.37	6.37	6.37	114,191,700	452,796	828,247	10,263,987	0.23	-0.76	28.05	-8.55	-0.41	0.00	0.33	1.11	2.45	2.85	72,925,544	-22,005,788	-3.31	6.79	10,733,902	2,704,626	12.67	-25,447,060	13,396,748	13,394,203	606,597	449,489	0.67	0.05	1.26	16,857,940	-16,104,659	-24,155,994	1.59	3.97	-5,448,954	-215.08	-205.01	-236.84	-32.25	3.77	0.43	0.00	-60.98	-174.97	330.70	1.00	0.00	0.02	14.90
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BLCM	Bellicum Pharmaceuticals Inc.	81.41	2,933	4.45	1	3.0	1.37	15.29	41.27	-74.26	2.62	16.60	3.37	5.81		0.00	0.00	4.50	4.50	4.50	22,212,430	285,975	589,969	217,358	-11.02	-3.52	-0.40	-1.18	0.01	0.00	1.00	-0.53	0.78	0.80	18,335,278	-51,352,000	-0.36	3.57	5,133,000	29,053,000	0.00	-55,486,000	5,059,779	4,542,417	251,845	337,787	0.28	0.04	10.50	53,125,000	-34,712,624	-56,009,000	-9.49	-0.47	-55,328,000	-1,057.41	0.00	0.00	0.00	1.65	0.29	0.00	-34.90	0.00	0.00	1.02	0.00	0.32	23.90
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BLRX	BioLineRx Ltd.	52.15	3,532	2.46	3	1.7	-0.81	-22.40	-2.77	2.07	1.06	3.72	2.54	2.00		0.00	0.00	5.00	4.03	2.20	0	1,864,292	1,985,143	2,270,152	-1.97	-1.38	-1.25	-1.78	0.04	0.00	0.51	0.54	2.02	2.05	36,519,748	-25,920,000	-1.41	0.00	0	8,324,000	33.55	-27,901,000	571,426,315	19,767,237	2,464,927	2,264,699	1.06	0.00	1.05	20,827,000	-12,110,125	-23,204,000	1.26	1.95	0	0.00	0.00	0.00	0.00	0.82	0.01	0.00	-32.04	-87.18	0.00	0.00	0.00	0.00	28.18
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BLUE	bluebird bio Inc.	123.78	2,111	46.07	19	2.0	-4.22	-6.95	-15.55	-44.37	38.95	94.50	45.81	55.61		0.00	0.00	48.00	80.21	46.47	3,192,557,000	1,129,626	1,119,280	1,094,460	-10.81	-11.09	-4.26	-4.15	-1.64	0.00	0.93	-0.56	6.39	6.57	2,022,857,856	-638,115,968	-3.17	8.09	250,023,008	195,292,992	12.82	-642,168,000	66,373,320	65,992,337	7,215,030	6,843,338	6.36	0.16	18.54	1,230,254,976	-289,652,256	-474,134,016	22.96	2.01	-540,717,000	-261.48	-255.22	-256.84	-147.04	4.04	0.19	0.00	-21.29	-42.89	116.30	4.21	0.00	0.50	97.56
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BMRN	BioMarin Pharmaceutical Inc.	404.35	276	85.91	20	2.1	-3.44	0.16	18.32	-0.52	68.25	131.95	82.89	93.04		0.00	0.00	84.00	110.90	188.00	16,150,690,000	1,543,000	1,490,728	1,809,418	4.33	0.08	19.85	1,073.88	0.01	0.00	0.86	0.35	2.24	3.21	15,594,326,016	35,086,000	444.46	8.37	1,862,781,056	1,504,785,024	37.12	852,025,024	181,529,667	180,244,437	11,185,475	11,869,326	7.15	0.07	8.29	1,505,672,960	-20,957,000	156,092,000	22.34	3.85	629,575,000	-3.68	1.88	45.74	38.89	3.45	0.02	12.31	-0.80	23.91	3.40	10.33	0.00	0.61	1.00
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BNTC	Benitec Biopharma Inc.	39.02	3,763	4.67	0	3.0	13.08	28.65	72.33	-34.46	2.52	17.42	3.15	5.81		0.00	0.00	0.00	0.00	0.00	18,194,590	2,815,844	644,574	226,404	-9.09	-3.44	-0.51	-1.36	0.01	0.00	0.40	0.35	7.33	7.91	11,102,587	-9,621,000	-1.15	89.54	124,000	359,000	4.64	-9,845,000	4,405,469	3,410,362	42,385	48,403	0.06	0.01	1.69	7,451,000	-4,603,875	-9,350,000	6.98	0.67	287,000	-7,907.26	0.00	0.00	162.10	13.22	0.19	0.00	-49.77	-80.93	66.70	0.11	0.00	16.04	9.17
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BPMC	Blueprint Medicines Corporation	494.33	154	96.91	14	1.9	-5.82	-5.32	0.39	46.57	43.29	125.61	107.73	85.74		0.00	0.00	81.00	118.00	152.00	5,734,700,000	300,105	505,352	519,714	5.43	-6.76	17.84	-14.34	-0.09	0.00	1.01	0.96	7.44	7.64	4,734,849,024	331,756,000	14.27	5.84	811,161,984	91,407,000	6.93	333,219,008	55,730,804	55,373,570	2,746,374	3,261,719	4.78	0.06	13.59	757,430,016	226,068,368	366,939,008	24.21	4.00	-264,938,000	40.10	40.90	41.08	58.28	6.01	0.21	0.00	17.71	36.29	8,053.20	15.36	0.00	0.79	1.04
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BPTH	Bio-Path Holdings Inc.	104.84	2,456	4.55	1	0.0	4.12	14.04	35.02	-35.98	2.92	7.16	3.75	4.50		0.00	0.00	10.00	10.00	10.00	19,869,260	608,514	275,128	432,882	-3.00	-2.20	-1.52	-1.94	0.06	0.00	0.53	0.05	8.45	10.03	7,687,729	-10,698,000	-0.72	0.00	0	352,000	2.67	-10,721,000	4,541,857	4,495,439	252,788	241,751	0.88	0.06	2.66	12,058,000	-6,544,250	-10,613,000	3.57	1.27	0	0.00	0.00	0.00	0.00	4.13	0.14	0.00	-41.46	-73.41	0.00	0.00	0.00	1.02	7.77
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BTAI	BioXcel Therapeutics Inc.	175.53	1,413	51.37	10	1.5	3.01	6.60	1.30	194.38	13.77	71.50	48.89	46.78		0.00	0.00	68.00	112.00	58.89	1,215,250,000	401,952	492,239	547,302	-3.45	-4.19	-14.89	-12.26	-0.69	0.00	1.28	1.49	14.28	14.45	984,174,976	-68,379,000	-14.39	0.00	0	2,353,000	1.07	-69,358,000	24,368,357	14,877,613	3,329,690	3,268,310	7.79	0.23	9.58	233,428,000	-27,863,500	-54,176,000	9.07	5.66	0	0.00	0.00	0.00	0.00	2.24	0.78	0.00	-30.30	-54.32	0.00	0.00	0.00	39.80	53.92
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	BYSI	BeyondSpring Inc.	118.79	2,191	13.06	6	1.4	-2.90	2.11	-9.93	0.00	9.38	21.50	12.01	13.76		0.00	0.00	25.00	32.83	13.69	526,451,800	261,119	567,496	229,764	-2.03	-2.44	-6.43	-5.35	-0.32	0.00	0.83	0.23	2.41	2.78	382,801,600	-60,811,000	-6.30	0.00	0	4,351,000	18.98	-57,450,000	39,141,401	16,066,580	987,479	1,218,917	1.96	0.04	1.01	30,874,000	-26,588,500	-49,465,000	0.79	16.57	0	0.00	0.00	0.00	0.00	2.84	0.07	0.00	-103.49	-267.71	0.00	0.00	0.00	71.55	6.20
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CABA	Cabaletta Bio Inc.	156.50	1,642	12.78	3	2.0	-8.97	-10.82	3.73	-19.34	5.51	19.63	13.85	11.07		0.00	0.00	20.00	20.33	21.00	337,738,800	92,851	105,787	115,700	-10.97	-1.94	-1.17	-7.24	0.01	0.00	0.99	0.11	27.37	27.95	225,327,744	-30,068,000	-7.49	0.00	0	0	0.00	-29,433,000	24,055,467	7,477,161	1,431,194	1,297,574	11.87	0.07	4.85	116,741,000	-16,044,875	-25,480,000	-6.78	-1.89	0	0.00	0.00	0.00	0.00	8.87	0.14	0.00	-19.29	-31.08	0.00	0.00	0.00	5.23	67.40
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CALA	Calithera Biosciences Inc.	63.97	3,285	3.06	5	1.7	-4.67	-1.29	-13.31	0.00	2.46	8.18	4.31	4.73		0.00	0.00	2.00	5.00	3.18	226,493,500	1,581,450	1,683,281	942,110	-1.38	-0.97	-2.23	-3.15	0.08	0.00	1.26	-0.26	6.98	7.07	88,137,008	-90,782,000	-0.97	0.00	0	7,154,000	5.84	-89,299,000	70,558,711	61,545,541	3,218,099	1,905,939	3.55	0.08	1.95	137,748,992	-47,181,624	-79,706,000	1.74	1.76	-76,290,000	0.00	0.00	0.00	0.00	4.46	0.24	0.00	-38.76	-73.42	0.00	0.00	0.00	0.72	81.73
HEALTH CARE	Biotechnology	Biotechnology	AMEX	CANF	Can-Fite Biopharma Ltd	170.26	1,467	2.05	2	2.0	-1.91	10.22	22.02	0.00	1.08	2.95	1.87	1.93		0.00	0.00	5.00	5.00	5.00	0	359,168	536,305	921,049	-1.47	-0.68	-1.39	-3.01	0.03	0.00	0.11	0.45	7.28	7.28	21,985,222	-15,179,000	-1.45	27.31	805,000	49,000	0.51	-13,271,000	463,769,463	14,763,820	289,851	299,992	0.45	0.00	0.67	10,279,000	0	0	0.63	3.25	2,032,000	-1,887.33	0.00	0.00	100.00	1.87	0.05	0.00	-75.73	-151.30	-81.70	0.09	0.00	1.19	6.52
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CAPR	Capricor Therapeutics Inc.	40.81	3,726	6.35	0	2.0	-17.53	16.73	54.50	252.47	0.88	12.32	4.41	4.98		0.00	0.00	0.00	0.00	0.00	157,445,800	3,439,488	957,925	2,933,334	-0.95	-1.01	-6.70	-5.65	-1.02	0.00	1.52	1.22	15.50	15.58	81,773,064	-10,848,275	-7.54	172.33	474,520	318,160	1.05	-10,948,514	20,447,504	19,930,796	757,971	1,086,868	1.49	0.04	1.73	35,300,340	-3,982,022	-7,997,445	1.50	4.22	-4,136,777	-2,316.62	0.00	0.00	0.00	18.69	1.22	0.00	-31.16	-64.44	-88.10	0.04	0.00	2.53	6.20
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CASI	CASI Pharmaceuticals Inc.	205.90	1,108	3.63	3	1.5	4.91	4.61	80.60	0.00	1.15	3.60	2.71	2.17		0.00	0.00	3.50	4.00	5.00	428,845,600	1,375,556	481,971	404,091	-0.45	-0.24	-8.07	-15.13	0.17	0.00	0.93	0.65	14.49	14.99	376,091,648	-32,505,000	-11.57	32.25	11,663,000	2,363,000	2.10	-46,581,000	123,943,829	76,240,328	1,846,906	1,862,047	4.19	0.02	0.62	76,388,000	-30,118,876	-22,672,000	0.74	4.92	196,000	-294.94	-278.70	0.00	24.18	4.82	0.11	0.00	-17.67	-42.85	52.20	0.11	0.00	34.98	32.16
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CATB	Catabasis Pharmaceuticals Inc.	38.23	3,776	2.65	1	3.0	-3.64	-0.38	97.76	-50.72	1.25	8.59	2.06	4.99		0.00	0.00	2.40	2.40	2.40	55,231,930	845,353	5,702,203	1,857,872	-2.14	-0.69	-1.24	-3.96	0.02	0.00	0.80	0.06	7.57	7.95	3,181,240	-35,181,500	-0.09	0.00	0	1,207,000	2.45	-34,932,000	20,084,337	20,058,027	1,721,363	469,953	0.16	0.10	2.63	52,856,000	-19,487,500	-32,194,000	2.46	1.08	0	0.00	0.00	0.00	0.00	3.43	0.22	0.00	-43.71	-79.77	0.00	0.00	0.00	0.13	40.64
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CBIO	Catalyst Biosciences Inc.	254.40	776	6.33	4	2.0	-7.32	-4.38	15.93	5.05	3.43	8.94	6.27	5.85		0.00	0.00	6.45	7.32	18.00	150,928,100	221,846	249,578	276,376	-3.06	-3.32	-2.07	-2.07	-0.24	0.00	1.12	0.37	6.21	6.42	50,153,044	-51,589,000	-0.97	2.65	18,917,000	1,444,000	1.54	-50,944,000	22,097,820	17,836,255	585,288	912,042	1.97	0.03	4.66	102,882,000	-22,250,500	-41,023,000	4.26	1.49	-43,859,000	-273.38	-272.71	-269.30	-193.62	7.31	0.04	0.00	-31.75	-58.11	0.00	1.14	0.00	4.55	64.58
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CBMG	Cellular Biomedicine Group Inc.	30.35	3,890	17.96	1	3.0	-0.99	-1.10	0.62	6.85	11.48	19.50	18.24	16.62		0.00	0.00	19.00	19.00	19.00	353,331,800	88,381	36,747	84,912	-2.83	-2.63	-6.35	-6.94	0.90	0.00	0.91	0.39	0.45	0.47	395,304,448	-48,654,368	-8.13	1,224.04	322,950	66,392,252	383.25	-54,804,252	19,478,048	8,953,701	301,601	346,566	7.47	0.03	1.34	26,028,896	-17,590,566	-44,458,880	0.89	20.16	277,542	-17,044.12	0.00	0.00	80.83	1.01	0.03	0.00	-34.66	-129.91	0.00	0.02	0.00	44.70	33.84
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CBPO	China Biologic Products Holdings Inc.	55.47	3,454	118.40	4	3.0	0.00	0.02	2.03	2.00	97.91	119.29	118.06	111.11		0.00	0.00	77.00	102.78	119.00	4,592,511,000	146,151	157,833	110,309	3.56	5.34	33.24	22.15	-2.09	0.00	0.10	0.21	9.96	12.01	3,573,229,056	208,593,280	17.13	6.95	514,397,248	0	0.00	139,371,952	38,788,096	13,045,212	402,011	414,717	2.86	0.02	28.45	1,103,345,920	189,434,496	261,408,080	48.63	2.43	329,078,378	35.25	40.55	27.42	64.90	0.01	0.01	-18.20	5.62	8.94	1.80	13.35	0.00	45.59	50.29
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CCXI	ChemoCentryx Inc.	179.99	1,357	59.29	8	1.6	-8.53	-2.61	22.83	58.54	30.72	67.43	59.75	56.14		0.00	0.00	60.00	80.63	119.00	4,486,089,000	531,027	517,238	613,876	-0.65	-1.47	-90.66	-43.81	-0.73	0.00	1.14	0.93	10.06	10.12	4,045,652,736	-41,180,000	-98.24	57.32	70,580,000	60,015,000	14.83	-41,008,000	69,208,414	48,090,159	5,265,939	5,061,740	9.40	0.11	6.81	471,384,000	-27,122,500	-82,149,000	5.86	10.12	-34,148,000	-59.11	-58.35	-58.10	-7.48	8.71	0.22	0.00	-7.00	-17.57	-51.90	1.12	0.00	23.49	81.82
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CDMO	Avid Bioservices Inc.	126.31	2,076	14.09	3	1.7	-4.15	0.57	77.23	111.11	3.02	14.78	11.28	8.02		0.00	0.00	12.00	14.33	16.00	890,170,000	437,027	520,510	414,716	-0.08	0.06	-176.13	237.50	1.01	0.00	1.07	1.36	1.20	1.45	794,564,288	3,241,000	245.16	10.95	72,591,000	21,876,000	44.30	-4,544,000	60,559,669	45,673,775	2,252,934	2,076,152	3.51	0.04	0.63	35,664,000	5,166,125	10,544,000	0.87	16.18	3,932,000	-0.09	4.47	0.20	19.90	4.58	0.45	0.00	-0.04	0.29	15.00	1.28	0.00	6.98	63.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CDNA	CareDx Inc.	193.77	1,200	78.96	6	1.5	-7.87	-15.40	59.71	257.83	13.04	99.83	70.69	44.20		0.00	0.00	55.00	82.83	101.00	4,375,450,000	845,041	720,506	624,449	-0.45	0.38	-177.04	207.79	0.96	0.00	1.29	2.01	3.92	4.14	4,026,079,488	-17,970,000	-224.04	23.77	169,371,008	18,534,000	6.90	-19,976,000	51,180,293	48,447,920	4,691,188	4,688,311	6.28	0.11	4.34	213,798,000	17,638,376	25,167,000	5.47	14.44	81,613,000	-14.59	-10.61	-11.79	58.20	8.82	0.99	0.00	-6.20	-10.91	57.80	3.78	0.00	1.68	1.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CDTX	Cidara Therapeutics Inc.	79.91	2,970	2.50	4	1.7	-3.10	1.63	2.46	0.00	1.30	4.45	2.27	3.05		0.00	0.00	4.00	6.25	3.18	113,359,700	510,669	440,579	300,059	-1.65	-1.65	-1.52	-1.52	-12.50	0.00	0.84	-0.36	1.54	1.78	77,123,728	-64,085,000	-1.20	7.60	10,153,000	9,284,000	31.42	-67,262,000	43,937,878	34,474,098	1,573,843	1,568,407	3.30	0.04	1.04	45,520,000	-42,969,124	-58,480,000	0.67	3.71	-25,486,000	-634.11	0.00	0.00	0.00	2.94	0.17	0.00	-55.36	-164.30	-87.40	0.25	0.00	17.54	65.31
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CELC	Celcuity Inc.	124.06	2,109	13.28	2	2.0	-1.63	-5.08	147.76	25.15	4.03	16.19	10.84	7.41		0.00	0.00	14.00	16.50	19.00	139,009,500	6,050	11,265	16,488	-0.85	-1.06	-15.61	-13.57	-0.64	0.00	0.83	0.62	13.44	13.54	134,664,432	-8,521,584	-15.80	0.00	0	311,995	2.27	-8,732,307	10,296,998	5,404,894	18,986	27,498	2.16	0.00	1.33	13,718,396	-3,645,574	-6,742,196	1.34	9.93	0	0.00	0.00	0.00	0.00	1.69	0.07	0.00	-30.36	-50.66	0.00	0.00	0.00	51.18	18.58
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CFRX	ContraFect Corporation	62.21	3,329	5.41	4	2.0	-0.19	4.24	4.24	0.00	4.45	12.10	5.39	5.72		0.00	0.00	12.00	5.65	7.00	150,730,600	168,849	212,810	253,093	-1.77	-1.05	-3.05	-5.15	0.08	0.00	1.08	-0.26	10.57	11.61	104,175,192	-29,842,768	-3.49	0.00	0	3,679,305	20.00	-32,106,776	27,810,082	21,527,506	1,932,697	1,530,034	8.55	0.08	1.81	50,234,756	-20,447,652	-33,309,668	0.66	8.17	-1,698,063	0.00	0.00	0.00	0.00	0.18	0.18	0.00	-48.44	-283.93	0.00	0.00	0.00	8.76	62.53
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CGIX	Cancer Genetics Inc.	82.87	2,909	3.91	0	3.0	-1.76	16.72	72.25	2.43	1.92	10.39	2.87	3.31		0.00	0.00	0.00	0.00	0.00	16,259,509	181,370	832,833	836,060	-2.07	-0.06	-1.89	-70.17	0.02	0.00	0.93	0.66	0.40	0.59	16,202,300	-2,945,000	-5.50	2.56	6,329,000	180,000	3.75	-4,215,000	4,085,303	3,733,906	120,804	16,043	0.14	0.03	0.28	1,133,000	3,403,000	-6,095,000	1.92	2.04	3,604,000	-57.50	-46.53	-71.50	47.26	1.74	0.03	0.00	-14.90	-68.71	-24.20	2.90	0.00	7.49	16.92
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CHRS	Coherus BioSciences Inc.	407.73	271	20.43	10	1.9	4.50	13.31	19.61	0.00	10.86	23.03	17.95	17.87		0.00	0.00	19.00	29.90	35.00	1,408,539,000	1,639,869	918,655	1,222,732	2.02	1.06	10.13	17.29	-0.25	0.00	1.03	0.44	4.98	5.45	1,234,023,040	188,140,000	6.56	2.52	489,260,992	416,814,016	162.99	161,763,008	72,048,012	60,208,362	15,493,637	15,189,056	19.61	0.26	6.99	503,431,008	51,805,876	138,731,008	3.55	5.75	244,915,000	37.82	38.45	33.06	65.91	4.47	0.05	-47.20	20.45	103.78	1.70	6.90	0.00	1.62	1.26
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CKPT	Checkpoint Therapeutics Inc.	291.85	596	3.42	3	1.7	-0.29	1.48	43.10	103.37	1.05	4.50	2.74	2.36		0.00	0.00	5.09	5.62	6.37	232,839,700	717,386	797,443	772,138	-0.43	-0.35	-7.92	-10.34	0.42	0.00	1.24	1.13	6.55	6.64	211,175,728	0	0.00	197.92	1,067,000	0	0.00	-21,682,000	60,883,303	52,483,297	2,046,556	2,129,328	2.44	0.04	0.62	42,029,000	-11,850,000	-16,346,000	0.53	6.40	-17,617,000	-2,044.61	0.00	0.00	0.00	0.66	0.37	0.00	-48.07	-102.05	-90.00	0.02	0.00	12.62	21.39
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLBS	Caladrius Biosciences Inc.	81.99	2,923	2.23	3	2.3	-2.62	36.81	40.25	-17.87	1.05	4.89	1.62	1.88		0.00	0.00	1.40	2.86	6.00	44,416,790	1,393,204	3,121,664	1,195,994	-0.58	-0.48	-3.84	-4.77	0.22	0.00	0.46	0.30	9.63	9.87	6,544,385	-18,720,000	-0.35	0.00	0	710,000	1.89	-7,675,000	19,395,977	15,792,592	144,669	152,252	0.56	0.01	2.08	40,269,000	-12,356,250	-7,476,000	1.95	1.15	0	0.00	0.00	0.00	0.00	2.53	0.10	0.00	-31.86	-24.53	0.00	0.00	0.00	12.18	19.23
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLDX	Celldex Therapeutics Inc.	250.27	808	20.04	3	2.0	6.48	11.71	24.86	691.11	1.50	23.40	18.76	12.28		0.00	0.00	22.00	26.33	32.00	744,652,200	987,448	689,150	1,346,487	-2.03	-1.46	-9.89	-12.19	0.35	0.00	0.38	2.12	16.43	16.63	513,651,488	-47,661,000	-10.78	113.64	4,520,000	3,808,000	1.66	-48,327,000	39,567,264	29,277,650	4,808,298	2,434,792	5.84	0.12	5.04	199,594,000	-26,077,500	-46,193,000	5.81	3.45	-39,099,000	-1,150.00	0.00	0.00	0.00	3.36	3.13	0.00	-16.76	-29.17	22.30	0.19	0.00	0.16	82.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLLS	Cellectis S.A.	138.91	1,887	30.11	10	1.7	-3.80	-9.44	89.49	89.75	7.32	34.71	27.41	19.73		0.00	0.00	11.00	35.10	50.00	1,313,084,000	223,266	409,569	244,194	-1.87	-2.33	-16.10	-13.42	-0.65	0.00	1.16	1.13	5.20	6.11	1,154,287,360	-86,483,000	-13.35	15.84	72,894,000	71,688,000	21.98	-78,993,000	42,489,133	26,322,284	782,057	911,235	1.46	0.00	6.63	281,783,008	-47,825,376	-49,256,000	6.83	4.41	11,598,000	-117.81	-118.64	-108.37	67.28	4.13	0.34	0.00	-11.12	-26.37	-9.40	1.72	0.00	0.00	33.88
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLRB	Cellectar Biosciences Inc.	105.41	2,438	1.86	6	1.7	-2.62	-5.10	66.07	-27.07	1.01	3.33	1.86	1.46		0.00	0.00	1.90	3.00	3.18	86,795,610	1,809,815	2,563,186	1,153,557	-1.01	-0.52	-1.85	-3.67	0.04	0.00	0.74	0.14	4.76	5.01	34,958,264	-14,656,289	-2.39	0.00	0	633,632	3.91	-14,858,999	45,409,104	21,335,308	2,527,710	1,014,910	0.60	0.06	0.70	18,841,944	-7,144,850	-12,745,199	0.56	3.31	0	0.00	0.00	0.00	0.00	2.50	0.13	0.00	-50.87	-104.44	0.00	0.00	0.00	13.66	24.14
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLSN	Celsion Corporation	82.32	2,918	1.78	2	2.0	27.14	95.60	263.27	19.46	0.43	6.50	0.77	1.36		0.00	0.00	3.00	4.00	5.00	52,997,760	43,940,362	8,786,329	3,806,251	-0.75	-0.45	-2.38	-3.96	0.06	0.00	0.31	0.92	3.38	3.67	54,551,980	-17,683,700	-3.09	109.10	500,000	6,288,174	33.70	-21,574,168	37,417,716	36,935,776	1,538,263	1,111,078	0.50	0.05	0.49	18,339,728	-11,665,643	-17,503,676	0.52	3.45	-12,565,309	-3,688.04	0.00	0.00	0.00	27.07	0.18	0.00	-29.61	-126.47	0.00	0.02	0.00	1.25	17.99
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLVS	Clovis Oncology Inc.	93.30	2,714	8.21	6	3.3	3.92	34.15	59.73	-22.05	3.62	11.63	5.15	6.17		0.00	0.00	3.00	7.33	15.00	697,719,800	15,150,857	5,712,263	5,587,258	-5.01	-2.46	-1.64	-2.72	0.03	0.00	1.14	0.49	2.05	2.33	1,000,281,664	-320,676,000	-3.12	6.23	160,530,000	635,012,992	0.00	-369,755,008	88,318,959	80,679,369	36,694,330	33,640,719	6.73	0.36	2.54	224,702,000	-130,380,624	-266,822,000	-1.85	-4.44	113,080,000	-204.86	-199.76	-230.33	78.45	3.94	0.03	0.00	-31.38	0.00	3.10	2.17	0.00	2.08	60.69
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CLXT	Calyxt Inc.	266.05	718	10.88	6	2.0	15.99	34.16	217.20	38.77	2.40	10.45	4.64	4.82		0.00	0.00	6.00	7.83	10.00	347,670,100	747,712	266,516	147,148	-1.32	-0.88	-8.24	-8.99	0.25	0.00	1.07	1.13	3.84	4.83	278,071,136	-40,446,000	-6.88	20.32	13,688,000	19,901,000	57.03	-43,606,000	37,065,044	12,828,212	454,965	416,206	2.22	0.04	0.76	27,972,000	-23,759,750	-38,261,000	1.05	10.36	-1,984,000	-309.57	-295.49	0.00	-58.39	15.63	0.42	0.00	-33.34	-81.49	76.60	0.41	0.00	65.12	21.40
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CMRX	Chimerix Inc.	256.52	758	9.15	3	2.3	1.67	12.96	224.47	422.86	1.19	10.72	5.40	3.49		0.00	0.00	3.00	9.67	16.00	685,435,200	1,079,125	1,209,050	830,504	-0.57	-0.75	-16.02	-12.20	-0.51	0.00	0.96	1.89	11.89	12.18	478,954,016	-36,210,000	-13.23	43.47	11,019,000	3,014,000	3.62	-35,350,000	83,122,658	54,020,477	888,605	945,223	1.34	0.02	1.40	87,765,000	-17,690,000	-30,462,000	1.33	6.89	-25,972,000	-332.44	0.00	0.00	-217.98	1.56	1.55	0.00	-20.70	-36.24	-17.80	0.18	0.00	18.34	53.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CNCE	Concert Pharmaceuticals Inc.	461.13	186	10.60	6	1.8	-4.76	-2.75	11.81	2.16	5.47	13.50	11.75	10.48		0.00	0.00	18.00	24.00	30.00	341,126,100	149,834	178,538	145,660	-2.51	-3.08	-4.22	-3.44	-0.19	0.00	0.82	0.47	17.64	18.51	230,189,136	-70,480,000	-3.27	29.11	7,908,000	16,190,000	12.65	-72,863,000	30,649,249	23,603,293	785,955	798,014	4.23	0.03	4.15	127,127,000	-45,143,000	-67,885,000	4.29	2.47	-58,739,000	-911.68	0.00	0.00	0.00	4.79	0.05	0.00	-29.52	-58.95	14,910.00	0.27	0.00	10.25	70.92
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CNST	Constellation Pharmaceuticals Inc.	123.50	2,116	35.11	9	2.1	-1.43	-3.81	71.69	0.00	17.00	50.90	28.82	28.62		0.00	0.00	23.00	45.67	75.00	1,694,640,000	412,335	672,004	616,592	-2.71	-3.33	-12.96	-10.23	-0.57	0.00	0.62	0.35	15.65	15.81	1,170,782,976	-112,377,000	-10.42	0.00	0	39,239,000	8.86	-113,187,000	47,575,521	28,428,277	5,304,361	5,745,951	6.31	0.16	10.29	489,353,984	-55,475,248	-94,831,000	9.31	3.77	0	0.00	0.00	0.00	0.00	1.41	0.03	0.00	-23.13	-46.11	0.00	0.00	0.00	0.75	1.04
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CPRX	Catalyst Pharmaceuticals Inc.	491.77	155	3.70	5	2.0	-0.27	3.35	19.36	-14.55	2.55	5.28	3.53	3.89		0.00	0.00	5.50	7.40	9.00	384,534,900	1,351,481	1,790,891	1,795,335	0.67	0.36	5.51	10.28	0.03	0.00	1.43	0.27	7.31	7.86	257,540,752	40,792,384	6.31	2.18	118,180,448	114,563	0.07	71,475,584	103,648,224	86,410,488	10,156,602	12,820,316	5.02	0.11	1.23	127,108,720	29,936,448	44,220,736	1.51	2.45	87,547,198	34.43	34.52	60.48	85.98	0.24	0.03	2.15	18.73	60.93	-5.10	1.14	0.00	6.98	69.58
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRBP	Corbus Pharmaceuticals Holdings Inc.	77.91	3,017	1.97	4	2.8	-2.48	13.87	84.11	-69.67	0.91	9.78	1.44	4.41		0.00	0.00	1.22	1.88	3.00	169,755,200	7,576,448	7,858,500	4,243,198	-1.78	-0.73	-1.10	-2.70	0.02	0.00	1.27	-0.07	2.00	2.06	114,067,392	-128,073,200	-0.89	19.49	5,852,546	26,182,818	89.59	-129,238,232	84,037,239	77,472,250	16,164,394	35,331,350	2.12	0.24	0.97	81,870,648	-58,400,720	-104,023,264	0.36	5.53	-53,461,222	-2,207.39	0.00	0.00	0.00	2.20	0.29	0.00	-98.49	-439.09	-52.50	0.08	0.00	1.73	75.49
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRIS	Curis Inc.	63.58	3,298	9.99	4	2.0	-2.73	-19.04	808.18	580.75	0.62	13.44	6.49	2.45		0.00	0.00	14.00	15.75	18.00	845,272,900	1,893,703	11,464,042	4,312,072	-0.77	-0.40	-13.04	-27.40	0.27	0.00	0.46	1.18	2.88	3.10	629,010,176	-25,813,000	-24.37	56.68	11,098,000	7,926,000	0.00	-30,999,000	84,469,618	51,418,210	1,706,513	377,684	0.07	0.02	0.40	23,555,000	-14,771,875	-25,623,000	-0.51	-19.78	-12,801,000	-233.89	-232.59	-279.32	-129.45	4.78	2.07	0.00	-36.89	0.00	-4.00	0.27	0.00	6.90	26.31
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRNX	Crinetics Pharmaceuticals Inc.	325.34	475	15.06	5	2.0	-1.18	-0.20	15.31	-32.27	10.63	24.46	13.83	15.41		0.00	0.00	23.00	33.60	42.00	501,736,300	65,406	164,412	172,249	-2.36	-2.36	-6.38	-6.45	150.60	0.00	1.11	-0.07	21.35	21.98	319,297,824	-67,424,000	-4.74	814.54	392,000	5,044,000	2.69	-66,720,000	32,922,328	18,438,479	1,441,471	1,295,745	8.39	0.06	5.68	186,824,000	-35,423,000	-59,536,000	5.69	2.65	-40,313,000	-17,442.86	0.00	0.00	0.00	1.05	0.13	0.00	-24.93	-42.13	0.00	0.01	0.00	4.50	95.14
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRSP	CRISPR Therapeutics AG	45.46	3,643	169.53	16	2.4	-6.46	-14.50	95.27	212.79	32.30	220.20	153.01	98.00		0.00	0.00	45.00	146.56	210.00	13,396,330,000	2,464,849	1,981,474	1,244,439	-3.39	-5.31	-50.07	-31.93	-0.88	0.00	0.92	2.01	16.23	16.53	11,488,266,240	-227,640,992	-50.47	148.49	77,365,000	49,210,000	3.66	-211,284,000	73,914,844	63,521,479	3,873,450	4,305,175	1.78	0.06	19.33	1,365,990,016	-85,448,872	-153,778,000	19.03	8.91	110,228,000	-304.65	-294.24	-273.10	-201.61	7.32	0.88	0.00	-13.36	-21.84	-99.90	1.24	0.00	13.71	68.49
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRTX	Cortexyme Inc.	60.05	3,369	37.36	8	2.2	18.00	13.04	-16.51	-41.21	26.66	73.84	37.27	44.30		0.00	0.00	14.00	21.30	75.75	933,906,700	609,718	264,096	155,513	0.33	-2.91	112.00	-11.03	4.71	0.00	1.09	0.02	8.40	8.71	799,585,472	-70,667,000	-11.32	0.00	0	523,000	0.28	-68,673,000	29,497,999	15,754,586	2,897,495	2,007,428	7.43	0.19	4.67	137,794,000	-25,286,750	-48,492,000	6.37	5.86	0	0.00	0.00	0.00	0.00	18.13	0.20	0.00	-26.25	-43.56	0.00	0.00	0.00	45.68	55.64
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CRVS	Corvus Pharmaceuticals Inc.	128.04	2,043	3.88	5	1.6	-2.02	4.58	-4.90	-27.81	1.01	6.88	3.96	3.74		0.00	0.00	4.77	6.00	9.20	111,125,100	233,075	190,783	1,008,180	-1.51	-1.55	-2.57	-2.61	-0.95	0.00	0.86	0.23	4.29	4.38	64,826,696	-44,646,000	-1.45	0.00	0	2,537,000	5.99	-44,389,000	28,061,900	14,896,940	1,198,922	1,382,021	6.04	0.09	1.83	51,361,000	-18,904,624	-35,081,000	1.51	2.57	0	0.00	0.00	0.00	0.00	1.90	0.13	0.00	-38.19	-72.32	0.00	0.00	0.00	4.98	63.75
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CTIC	CTI BioPharma Corp.	171.03	1,459	3.33	4	2.0	-1.19	5.05	0.60	180.83	0.62	4.03	3.42	2.04		0.00	0.00	4.00	4.14	7.70	254,338,500	417,097	581,073	1,507,291	-0.68	-0.76	-4.89	-4.43	-0.42	0.00	0.46	1.26	3.95	4.04	201,827,568	-37,714,000	-5.35	0.00	0	10,713,000	22.88	-45,637,000	75,471,355	48,248,815	739,403	593,039	1.31	0.01	0.78	57,412,000	-27,633,250	-42,871,000	0.64	5.24	3,345,000	0.00	0.00	0.00	0.00	1.89	0.71	0.00	-39.29	-125.01	0.00	0.00	0.00	0.26	56.82
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CTMX	CytomX Therapeutics Inc.	554.36	106	6.90	8	2.3	-2.82	-18.63	2.53	-8.02	3.60	15.44	7.40	7.90		0.00	0.00	8.50	12.56	18.00	328,193,200	1,540,874	734,595	582,475	-1.17	-2.20	-5.90	-3.23	-0.07	0.00	1.31	0.43	3.28	3.34	11,937,273	-68,686,000	-0.17	0.13	92,268,000	25,621,000	53.31	-53,640,000	60,510,116	36,842,235	2,898,580	3,289,385	4.68	0.06	6.95	321,076,000	-13,707,125	-6,793,000	1.04	6.63	57,489,000	-77.17	-74.44	-58.14	100.00	2.80	0.03	0.00	-11.90	-82.41	66.10	2.01	0.00	2.89	83.50
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CUE	Cue Biopharma Inc.	290.15	605	14.00	6	1.3	-6.36	-4.57	23.89	-9.28	9.30	31.69	13.04	18.56		0.00	0.00	27.00	31.17	40.00	452,661,600	927,702	299,968	308,831	-1.57	-1.55	-8.92	-9.65	7.37	0.00	1.11	0.30	6.49	6.58	342,415,616	-42,073,464	-8.14	91.84	3,728,331	8,202,000	9.37	-42,598,956	30,278,366	21,973,313	2,759,922	2,858,180	8.73	0.09	3.03	91,803,000	-11,349,808	-31,932,910	2.89	4.84	-24,029,154	-1,155.56	0.00	0.00	0.00	6.32	0.06	0.00	-35.47	-74.36	-28.50	0.14	0.00	10.76	65.25
HEALTH CARE	Biotechnology	Biotechnology	AMEX	CVM	Cel-Sci Corporation	50.88	3,550	14.49	1	2.0	-3.21	-3.46	31.13	5.00	6.35	18.00	13.19	13.44		0.00	0.00	19.00	19.00	19.00	595,153,600	647,070	591,313	631,189	-0.82	-0.11	-17.58	-131.73	0.20	0.00	0.61	0.56	3.65	4.15	593,582,208	-26,825,326	-22.13	1,062.50	558,664	13,937,563	70.65	-30,276,978	39,756,417	37,963,403	10,623,754	10,189,837	15.75	0.28	0.39	15,508,909	-8,801,720	-15,276,161	0.51	28.47	-17,281,626	-5,188.28	0.00	0.00	0.00	3.24	0.05	0.00	-53.16	-243.58	-62.70	0.02	0.00	4.20	30.86
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CWBR	CohBar Inc.	56.99	3,429	2.02	4	2.0	10.38	43.26	117.20	-22.77	0.85	4.25	1.34	1.60		0.00	0.00	2.03	3.00	3.18	106,073,000	3,285,676	592,117	487,991	-0.34	-0.33	-5.94	-5.24	2.02	0.00	0.56	0.47	10.00	10.26	75,874,136	-12,242,933	-6.20	0.00	0	3,591,448	18.86	-15,273,730	61,117,524	44,528,070	2,222,599	1,886,443	4.77	0.05	0.40	23,356,932	-4,776,517	-9,467,107	0.33	6.16	0	0.00	0.00	0.00	0.00	10.70	0.08	0.00	-38.85	-101.77	0.00	0.00	0.00	24.48	12.34
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CYAD	Celyad Oncology SA	284.53	627	8.27	3	1.7	1.97	-5.49	-2.13	-28.21	4.10	13.01	8.49	9.44		0.00	0.00	15.05	17.73	20.06	0	36,789	14,453	13,970	-7.01	-4.12	-1.18	-2.01	0.03	0.00	1.02	0.10	2.67	2.73	115,303,184	0	0.00	0.00	0	0	12.22	0	14,205,156	9,223,976	210,053	213,340	13.94	0.00	0.00	0	0	0	7.09	1.17	6,000	0.00	0.00	0.00	100.00	2.08	0.12	0.00	-21.53	-82.16	0.00	0.00	0.00	0.00	8.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CYCC	Cyclacel Pharmaceuticals Inc.	60.66	3,358	7.56	0	1.7	2.86	0.13	130.49	-51.75	3.12	19.25	5.81	4.70		0.00	0.00	0.00	0.00	0.00	39,321,740	217,061	532,139	517,241	-3.12	-1.87	-2.42	-3.93	0.06	0.00	0.88	-0.00	14.78	15.15	14,074,401	-10,241,000	-1.37	0.00	0	1,063,000	4.35	-8,147,000	5,349,896	3,317,967	887,353	65,816	0.97	0.18	4.76	23,130,000	-6,349,750	-7,899,000	5.02	1.50	-4,658,000	0.00	0.00	0.00	0.00	3.06	0.21	0.00	-28.96	-41.50	0.00	0.00	0.00	2.81	22.42
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CYCN	Cyclerion Therapeutics Inc.	71.83	3,151	3.17	1	3.0	-4.52	-4.81	33.76	-4.83	2.08	8.96	3.13	4.41		0.00	0.00	4.00	4.00	4.00	112,753,400	194,849	322,034	359,355	-2.94	-0.27	-1.08	-12.41	0.01	0.00	1.20	0.61	4.14	4.31	92,681,024	-88,816,000	-1.04	25.43	3,644,000	46,428,000	61.61	-84,629,000	33,961,868	19,858,183	582,989	614,703	2.39	0.02	1.97	66,840,000	-45,826,000	-80,612,000	2.22	1.43	4,507,000	-2,505.38	0.00	0.00	100.00	4.48	0.06	0.00	-33.46	-87.00	-71.40	0.13	0.00	15.05	72.16
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	CYTK	Cytokinetics Incorporated	185.02	1,299	20.29	9	2.1	-2.64	2.01	21.35	69.24	8.00	30.14	19.06	20.42		0.00	0.00	21.00	27.00	41.00	1,475,035,000	569,762	1,062,611	1,167,842	-1.85	-1.98	-10.96	-10.28	-1.57	0.00	0.85	1.06	15.06	15.18	1,152,168,576	-79,491,000	-14.49	21.21	54,318,000	140,482,000	93.90	-114,000,000	70,779,023	70,435,037	9,307,581	8,962,432	8.06	0.16	5.80	410,264,000	-53,466,624	-62,262,000	2.12	9.58	-59,257,000	-149.57	-146.34	-209.88	-58.45	2.91	0.28	0.00	-15.35	-175.74	588.50	0.88	0.00	6.23	1.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DBVT	DBV Technologies S.A.	119.76	2,181	5.74	8	2.2	3.05	-12.63	178.64	-49.34	1.35	11.60	3.26	3.47		0.00	0.00	2.00	8.40	17.05	0	413,028	1,136,110	1,029,890	-3.27	-2.55	-1.76	-2.25	0.08	0.00	0.36	0.20	4.16	4.28	629,954,496	0	0.00	0.00	0	0	10.06	0	54,927,187	62,670,596	1,045,497	992,071	1.54	0.00	0.00	0	0	0	3.98	1.44	9,770,000	0.00	0.00	0.00	100.00	3.24	0.20	0.00	-35.72	-94.15	-11.90	0.00	0.00	0.00	33.81
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DCPH	Deciphera Pharmaceuticals Inc.	214.98	1,044	46.03	12	1.8	-4.24	-6.94	-24.12	-29.21	33.10	71.11	56.86	54.18		0.00	0.00	65.00	76.42	91.00	2,736,790,000	398,805	373,006	413,473	-4.99	-4.40	-9.23	-10.46	0.78	0.00	1.16	-0.19	9.11	9.34	2,222,868,736	-276,508,992	-8.04	98.35	22,601,000	31,404,000	5.52	-270,964,992	56,933,424	35,220,724	3,613,920	3,605,888	9.93	0.09	9.58	545,324,992	-146,799,008	-246,388,000	10.05	4.58	25,000,000	-1,232.53	0.00	0.00	-58.43	4.13	0.13	0.00	-26.60	-46.14	0.00	0.42	0.00	29.20	75.43
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DFFN	Diffusion Pharmaceuticals Inc.	214.39	1,052	1.27	2	0.0	-2.31	22.12	54.88	179.55	0.25	1.60	0.85	0.90		0.00	0.00	2.00	2.75	3.50	83,220,070	2,142,431	2,340,120	3,418,014	-0.38	-0.22	-3.32	-5.91	0.08	0.00	0.34	1.41	8.15	8.44	57,003,476	-14,742,253	-3.87	0.00	0	174,668	0.61	-15,825,707	64,015,441	63,827,236	864,346	678,407	0.76	0.01	0.34	21,910,184	-7,181,798	-12,596,064	0.45	2.83	0	0.00	0.00	0.00	0.00	3.05	0.76	0.00	-38.57	-65.69	0.00	0.00	0.00	0.21	10.71
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DMTK	DermTech Inc.	51.59	3,536	39.87	4	1.6	-12.34	-1.68	186.84	187.25	8.69	47.08	23.03	15.03		0.00	0.00	34.00	47.00	53.00	1,083,710,000	1,775,591	851,943	294,483	-3.34	-1.89	-11.93	-21.10	0.27	0.00	0.66	1.57	12.82	13.31	839,663,488	-29,603,000	-28.36	156.86	5,353,000	0	0.00	-30,921,000	23,832,594	12,001,929	1,164,497	657,702	1.44	0.09	2.63	51,531,000	-18,227,500	-28,017,000	1.58	25.25	60,000	-559.31	0.00	0.00	-2.00	13.04	0.75	0.00	-46.20	-86.93	141.10	0.36	0.00	23.57	57.65
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DNLI	Denali Therapeutics Inc.	91.59	2,744	72.98	10	2.2	-10.49	-3.95	59.14	228.22	12.39	93.94	74.47	41.78		0.00	0.00	18.00	68.20	101.00	9,776,955,000	520,119	728,134	642,230	-2.21	-1.95	-32.98	-37.43	2.77	0.00	1.12	1.57	9.12	9.21	8,885,668,864	-230,652,992	-38.52	377.86	23,516,000	69,915,000	7.92	-227,774,000	119,918,496	76,226,192	8,071,431	8,535,650	11.10	0.11	8.02	961,201,024	-37,421,752	-145,406,000	7.37	9.91	-166,704,000	-1,016.83	0.00	0.00	0.00	11.12	0.68	0.00	-17.86	-34.49	-31.00	0.23	0.00	17.61	78.64
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DRNA	Dicerna Pharmaceuticals Inc.	314.25	516	25.55	9	1.6	-0.97	9.19	17.47	29.76	11.75	27.10	23.45	21.69		0.00	0.00	25.00	35.78	45.00	1,936,158,000	706,355	677,515	641,048	-1.60	-1.06	-16.01	-24.10	0.48	0.00	0.85	0.78	2.57	2.62	1,347,833,344	-120,931,000	-11.15	10.33	130,431,000	21,588,000	14.05	-115,831,000	75,044,896	62,270,754	5,208,863	5,807,929	7.22	0.07	8.13	609,913,024	60,692,876	207,491,008	2.06	12.41	-85,435,000	-94.24	-92.72	-88.81	-42.74	1.11	0.14	0.00	-15.09	-80.42	508.30	1.80	0.00	7.32	79.66
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DTIL	Precision BioSciences Inc.	311.98	520	12.37	7	1.7	-6.92	-15.51	91.78	45.72	4.46	16.60	9.96	7.73		0.00	0.00	7.00	15.57	25.00	697,465,500	1,906,491	1,384,123	813,742	-2.06	-2.00	-6.00	-6.20	2.00	0.00	1.35	0.75	2.72	2.92	604,281,408	-99,813,000	-6.05	27.52	21,961,000	10,964,000	17.18	-106,469,000	52,480,469	42,744,817	4,215,324	2,111,085	2.66	0.09	1.99	104,148,000	-44,182,624	-94,490,000	1.22	10.17	22,238,000	-492.73	0.00	0.00	100.00	7.04	0.14	0.00	-31.53	-96.96	51.30	0.43	0.00	11.85	50.24
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DVAX	Dynavax Technologies Corporation	158.44	1,615	6.17	3	1.7	-5.80	20.98	54.25	22.18	1.80	12.44	4.90	5.62		0.00	0.00	14.00	16.00	6.37	721,632,200	4,440,939	3,147,228	4,808,376	-1.07	-0.45	-5.77	-13.71	0.10	0.00	0.88	0.67	3.19	4.35	721,006,528	-73,435,000	-9.82	19.19	37,571,000	218,400,992	315.23	-96,529,000	110,172,859	98,433,941	22,854,070	26,745,295	6.72	0.28	1.61	177,160,992	-87,629,248	-99,520,000	0.63	9.81	-37,284,000	-219.76	-195.46	-256.92	-9.36	5.87	0.09	0.00	-15.77	-178.03	26.80	0.40	0.00	0.76	80.86
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	DYAI	Dyadic International Inc.	144.15	1,811	5.65	3	2.0	-0.88	1.62	-19.52	1.62	2.51	10.98	5.86	7.10		0.00	0.00	10.00	11.00	12.00	156,648,300	95,604	246,970	202,517	-0.33	-0.32	-17.02	-17.66	4.71	0.00	0.60	0.34	17.89	18.12	126,240,896	0	0.00	74.74	1,689,172	0	0.00	-9,103,591	27,482,157	17,973,056	929,954	991,356	2.30	0.05	1.11	30,407,396	-4,496,559	-6,688,346	1.09	5.18	221,375	-572.11	0.00	0.00	5.63	0.84	0.04	0.00	-17.19	-27.08	-8.40	0.06	0.00	30.05	24.88
HEALTH CARE	Biotechnology	Biotechnology	NYSE	EBS	Emergent Biosolutions Inc.	456.75	188	109.37	7	2.0	2.82	2.34	17.87	94.92	46.37	137.61	91.90	93.55		0.00	0.00	86.00	111.57	144.00	5,637,519,000	496,262	557,201	691,729	3.11	9.27	35.17	11.80	-4.09	0.00	1.05	1.38	2.04	3.20	6,302,316,032	447,800,000	14.07	4.73	1,332,700,032	920,800,000	73.58	166,600,000	52,999,139	47,369,040	2,677,399	2,011,558	4.79	0.07	7.83	415,000,000	216,500,000	413,000,000	23.61	4.63	483,100,000	25.37	33.60	12.50	51.86	2.41	0.42	-12.00	8.54	14.57	23.50	25.47	0.00	14.71	83.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EDIT	Editas Medicine Inc.	112.75	2,316	60.68	8	2.8	-7.32	-15.85	114.34	135.11	14.01	99.95	57.62	37.01		0.00	0.00	14.00	44.38	86.00	4,333,382,000	2,581,410	2,872,094	1,436,732	-1.63	-3.32	-37.30	-19.81	-0.36	0.00	1.21	1.28	9.06	9.25	3,596,973,568	-104,832,000	-34.31	39.27	91,597,000	26,710,000	6.06	-91,247,000	66,188,823	61,028,661	9,890,638	11,057,054	2.79	0.16	8.01	495,304,992	-66,635,752	-98,719,000	7.14	8.50	-76,367,000	-118.33	-114.45	-99.62	-43.33	7.78	0.49	0.00	-13.98	-28.03	1,533.10	1.63	0.00	1.37	82.21
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EGRX	Eagle Pharmaceuticals Inc.	172.35	1,443	49.19	3	2.2	0.72	-1.90	-1.80	0.00	33.80	59.12	47.81	47.03		0.00	0.00	46.00	50.00	57.00	636,391,500	95,620	118,800	154,423	0.35	2.69	138.78	17.73	0.21	0.00	0.74	-0.05	3.23	3.60	570,835,200	29,590,000	19.29	3.07	186,144,000	38,979,000	22.56	4,937,000	13,030,130	10,884,458	1,491,443	1,496,369	10.89	0.19	6.88	89,681,000	30,398,876	26,536,000	13.26	3.71	134,995,000	14.00	15.90	2.65	76.09	0.77	0.05	0.00	6.45	2.83	21.30	13.66	0.00	22.24	99.11
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EIDX	Eidos Therapeutics Inc.	29.19	3,902	122.21	4	3.2	0.00	-4.63	67.25	133.67	28.39	132.54	109.35	65.64		0.00	0.00	34.00	71.81	129.00	4,750,656,000	0	142,534	136,137	-2.65	-3.41	-46.10	-35.84	-1.61	0.00	1.07	1.41	10.67	11.11	4,599,168,000	-97,572,000	-47.14	36,213.92	127,000	21,467,000	17.47	-100,829,000	38,861,923	13,306,708	495,615	637,073	3.16	0.04	3.81	147,327,008	-49,343,124	-85,072,000	3.18	38.39	24,191,000	-77,050.39	0.00	0.00	100.00	0.50	0.50	0.00	-35.95	-70.31	-99.50	0.00	0.00	65.26	31.08
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EIGR	Eiger BioPharmaceuticals Inc.	259.78	745	10.46	6	1.0	-1.60	-2.43	10.69	0.00	4.55	13.99	10.36	10.16		0.00	0.00	10.08	15.60	22.00	345,811,900	238,204	567,358	473,724	-2.42	-1.58	-4.32	-6.79	0.12	0.00	1.18	0.18	5.79	6.23	256,162,064	-60,559,000	-4.23	0.00	0	32,431,000	34.89	-63,165,000	32,531,693	27,712,448	1,481,835	1,789,714	2.56	0.05	3.85	125,334,000	-40,054,876	-62,641,000	2.91	3.59	0	0.00	0.00	0.00	0.00	1.52	0.08	0.00	-29.11	-76.75	0.00	0.00	0.00	1.27	74.50
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ENLV	Enlivex Therapeutics Ltd.	74.24	3,102	12.29	0	0.0	1.15	12.86	2.08	41.60	3.59	16.94	9.92	7.48		0.00	0.00	0.00	0.00	0.00	163,584,800	163,191	241,583	459,386	-0.74	-1.07	-16.54	-11.26	-0.38	0.00	0.22	0.86	6.61	7.23	134,744,448	-8,679,000	-15.53	0.00	0	682,000	2.39	-9,025,000	13,463,771	8,186,107	202,606	101,670	0.52	0.02	2.09	28,176,000	-4,035,375	-6,900,000	2.12	5.81	0	0.00	0.00	0.00	0.00	0.98	0.18	0.00	-21.22	-41.75	0.00	0.00	0.00	33.52	13.47
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ENTA	Enanta Pharmaceuticals Inc.	236.22	891	48.91	8	2.6	1.83	1.96	8.98	-11.37	38.40	58.59	44.16	47.82		0.00	0.00	30.00	61.75	107.00	967,459,000	103,148	156,948	162,903	-1.81	-5.71	-26.96	-8.57	-0.13	0.00	0.85	0.09	16.98	18.08	587,320,576	-37,995,000	-15.46	4.80	122,473,000	9,578,000	2.10	-36,168,000	20,142,806	15,125,266	2,407,437	2,357,865	14.09	0.15	19.26	386,648,992	9,553,625	7,088,000	22.69	2.16	122,473,000	-34.00	-31.02	-29.53	100.00	1.87	0.04	0.00	-5.33	-7.88	-53.90	6.14	0.00	11.87	95.30
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ENTX	Entera Bio Ltd.	123.13	2,124	1.57	1	2.0	-3.68	10.56	45.37	-48.84	1.00	3.40	1.18	1.53		0.00	0.00	4.00	4.00	4.00	34,335,820	283,800	668,370	428,593	-0.66	-0.68	-2.39	-2.31	-0.71	0.00	0.34	-0.22	2.42	2.67	23,078,056	-12,572,000	-1.84	93.81	246,000	216,000	3.76	-11,172,000	21,064,922	10,185,767	40,891	31,637	0.04	0.00	0.39	7,068,000	-6,325,000	-12,234,000	0.31	5.02	26,000	-5,141.06	0.00	0.00	13.82	3.49	0.20	0.00	-98.17	-228.51	-16.70	0.01	0.00	41.20	10.38
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EPZM	Epizyme Inc.	78.07	3,015	11.84	8	2.0	-1.50	0.25	-7.36	-46.40	9.90	25.98	12.02	14.14		0.00	0.00	11.46	12.00	23.00	1,221,008,000	614,395	959,559	995,115	-2.23	-2.15	-5.30	-5.59	1.43	0.00	1.29	-0.37	8.18	8.95	1,022,641,536	-217,876,000	-4.69	87.55	11,681,000	103,315,000	42.27	-221,863,008	101,581,358	82,851,787	10,575,368	10,616,987	8.83	0.14	2.76	279,907,008	-160,743,120	-188,704,992	2.05	5.78	-108,839,000	-1,889.94	0.00	0.00	0.00	1.32	0.18	0.00	-38.54	-82.45	-37.60	0.12	0.00	3.92	95.29
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ERYP	Erytech Pharma S.A.	95.01	2,683	11.77	2	1.7	9.90	-2.00	100.17	64.52	3.50	13.95	9.63	7.96		0.00	0.00	13.04	18.06	23.07	0	3,484	5,297	4,343	-2.79	-2.84	-4.22	-4.08	-2.18	0.00	0.45	0.98	0.00	0.00	192,283,216	0	0.00	0.00	0	0	32.31	0	20,057,562	11,126,035	1,126	14,103	0.21	0.00	0.00	0	0	0	10.64	1.11	5,283,000	0.00	0.00	0.00	100.00	9.64	0.29	0.00	0.00	0.00	13.60	0.00	0.00	0.00	7.05
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ESPR	Esperion Therapeutics Inc.	187.60	1,258	31.30	11	2.1	8.68	24.60	29.34	-49.44	23.90	76.98	28.44	36.54		0.00	0.00	19.10	32.00	72.00	802,846,800	1,355,576	717,145	675,199	-3.66	-10.44	-8.55	-2.48	-0.05	0.00	1.01	-0.26	2.84	3.20	685,001,920	-84,303,000	-8.13	3.13	218,891,008	177,908,992	1,985.59	-101,021,000	27,876,626	25,477,564	10,782,122	9,782,805	18.27	0.45	7.74	215,748,000	-48,782,752	-66,621,000	0.32	97.20	-27,247,000	-38.74	-38.51	-46.15	34.26	8.84	0.19	0.00	-20.94	-260.79	290.70	7.93	0.00	0.85	1.22
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ETTX	Entasis Therapeutics Holdings Inc.	439.34	209	3.53	7	1.9	2.62	19.66	110.12	-27.71	1.58	5.64	2.28	2.54		0.00	0.00	5.00	6.50	9.00	122,035,500	532,120	709,878	386,719	-2.92	-1.22	-1.21	-2.82	0.02	0.00	-0.20	0.50	9.14	9.97	63,370,780	-55,863,000	-1.13	0.00	0	1,461,000	2.35	-53,837,000	35,475,441	10,831,362	81,177	81,743	0.08	0.00	1.73	61,190,000	-27,088,500	-45,753,000	1.75	2.01	7,000,000	0.00	0.00	0.00	0.00	2.72	0.12	0.00	-52.54	-91.93	0.00	0.00	0.00	58.86	30.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EVGN	Evogene Ltd.	102.66	2,510	7.00	1	2.0	6.06	18.04	152.71	329.45	0.75	7.30	4.32	2.46		0.00	0.00	9.00	9.00	9.00	0	2,436,975	1,868,763	831,694	-0.82	0.45	-8.56	15.56	0.06	0.00	0.85	1.82	9.79	9.79	178,964,544	-22,516,000	-7.95	222.32	805,000	2,461,000	4.39	-21,330,000	36,491,379	28,815,380	980,092	371,912	0.46	0.03	1.37	43,494,000	-10,120,250	-17,304,000	1.42	4.93	419,000	-3,045.71	0.00	0.00	61.62	4.68	1.39	0.00	-21.52	-39.50	225.80	0.03	0.00	18.12	23.92
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EVLO	Evelo Biosciences Inc.	140.58	1,861	16.35	4	2.4	-1.86	5.62	281.12	131.71	3.01	17.66	9.49	5.80		0.00	0.00	11.00	17.50	27.00	769,512,700	232,088	392,649	202,759	-2.44	-1.77	-6.71	-8.88	0.25	0.00	0.94	1.32	6.02	6.24	686,086,912	-84,365,000	-8.13	0.00	0	42,034,000	83.35	-87,215,000	46,189,236	19,985,621	2,104,610	2,065,132	3.19	0.09	1.77	81,580,000	-42,978,248	-73,104,000	1.09	14.97	0	0.00	0.00	0.00	0.00	2.42	0.57	0.00	-49.98	-133.18	0.00	0.00	0.00	0.52	87.46
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EXAS	Exact Sciences Corporation	142.62	1,834	141.04	14	1.5	-8.37	-5.23	11.80	70.59	35.25	159.54	132.25	100.69		0.00	0.00	140.00	154.79	170.00	24,540,230,000	2,625,028	1,716,684	1,738,228	-2.27	-1.36	-62.13	-110.29	1.55	0.00	1.06	0.98	5.90	6.36	45,574,791,168	-50,381,000	-904.60	34.51	1,320,626,944	1,730,582,016	74.05	-333,750,016	168,351,524	297,433,444	9,762,506	10,783,101	5.71	0.07	4.27	1,283,001,984	19,979,124	-3,578,000	15.54	9.07	659,576,000	-15.14	-3.82	-25.27	75.39	8.61	0.27	0.00	-4.09	-21.63	86.60	8.98	0.00	0.91	93.33
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	EXEL	Exelixis Inc.	523.98	127	22.45	12	1.9	-1.62	-4.83	6.45	24.80	13.67	27.80	20.63	22.69		0.00	0.00	25.00	30.83	37.00	7,079,767,000	1,707,981	2,537,251	2,557,725	0.48	0.43	46.91	51.49	-4.59	0.00	0.80	0.70	6.75	6.99	5,728,546,304	175,170,000	32.70	5.98	957,795,968	47,626,000	2.57	152,136,000	310,243,961	282,083,117	14,450,633	14,914,764	6.41	0.05	3.83	1,187,880,960	250,321,872	333,710,016	5.99	3.75	935,978,000	17.35	18.29	15.88	96.38	1.73	0.11	0.00	5.33	8.81	-14.90	3.12	0.00	1.86	84.60
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FATE	Fate Therapeutics Inc.	107.15	2,406	89.31	16	1.7	-7.10	-21.87	95.98	0.00	16.75	121.16	85.15	48.02		0.00	0.00	30.00	88.69	135.00	8,857,137,000	858,408	1,267,488	1,003,681	-1.87	-1.81	-47.76	-53.70	14.89	0.00	1.34	1.88	9.08	9.17	8,075,931,648	-120,915,000	-66.79	440.35	18,340,000	85,486,000	20.14	-148,578,000	92,366,839	73,789,257	11,044,075	14,399,073	7.17	0.18	5.60	488,804,992	-30,327,750	-44,100,000	4.88	18.31	-77,090,000	-674.83	0.00	0.00	0.00	8.16	1.08	0.00	-16.00	-42.92	211.20	0.23	0.00	1.79	1.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FBIO	Fortress Biotech Inc.	192.86	1,210	3.34	6	2.0	-5.92	-7.22	48.44	0.00	1.04	4.78	3.04	3.00		0.00	0.00	4.50	5.09	8.92	332,645,200	588,399	797,111	1,061,648	-0.85	-0.56	-3.94	-6.32	0.12	0.00	1.21	0.80	6.30	6.38	274,510,112	-96,745,000	-2.84	6.39	42,980,000	82,154,000	46.64	-56,723,000	93,702,861	57,706,907	1,521,562	1,349,480	1.55	0.02	2.33	218,388,992	-45,598,500	-88,248,000	1.04	3.22	26,097,000	-233.48	-225.09	-131.98	67.72	6.06	0.17	0.00	-24.24	-91.94	-3.00	0.64	0.00	29.09	33.81
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FENC	Fennec Pharmaceuticals Inc.	187.06	1,272	7.68	4	1.5	-5.07	-2.91	-2.79	29.44	4.65	10.67	7.68	7.43		0.00	0.00	11.00	15.00	21.00	208,800,300	114,978	94,809	246,706	-0.83	3.19	-9.23	2.41	0.02	0.00	0.96	0.71	11.50	11.81	175,634,336	0	0.00	0.00	0	0	0.00	-18,481,000	25,809,684	19,712,662	994,647	1,206,672	9.28	0.06	1.29	33,166,000	-7,052,500	-13,901,000	1.21	6.36	0	0.00	0.00	0.00	0.00	5.17	0.12	0.00	-45.50	-80.03	0.00	0.00	0.00	16.83	54.27
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FGEN	FibroGen Inc	362.70	372	48.99	8	2.2	-1.21	11.29	22.41	0.00	22.65	51.56	41.45	41.10		0.00	0.00	44.00	61.88	91.00	4,513,222,000	961,709	749,532	710,288	-2.57	-0.94	-19.04	-50.60	0.30	0.00	1.22	0.58	6.03	6.23	3,720,973,824	-212,742,000	-17.49	31.19	119,294,000	61,099,000	12.97	-228,780,000	91,010,718	84,478,879	7,001,853	8,276,147	8.10	0.09	7.56	687,865,984	79,809,376	43,780,000	4.97	9.86	46,165,000	-196.42	-178.33	-191.78	-100.13	1.28	0.08	0.00	-17.17	-42.19	32.70	1.34	0.00	7.91	76.86
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FIXX	Homology Medicines Inc.	259.14	750	13.04	9	1.5	-4.05	-1.44	24.07	-14.88	8.70	22.38	11.30	12.51		0.00	0.00	15.00	28.44	37.00	615,135,700	228,645	644,800	515,700	-2.74	-2.69	-4.76	-4.85	2.51	0.00	1.13	0.24	10.39	10.55	453,121,696	-118,392,000	-3.83	198.30	2,285,000	16,037,000	9.42	-123,070,000	45,264,419	24,150,453	2,519,578	2,843,373	2.49	0.07	3.93	178,003,008	-68,365,504	-109,053,000	3.76	3.47	-87,732,000	-5,515.10	0.00	0.00	0.00	3.98	0.08	0.00	-28.90	-57.50	28.60	0.05	0.00	16.45	89.82
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FLXN	Flexion Therapeutics Inc.	288.28	617	12.36	12	1.8	1.06	3.26	3.00	-30.13	5.01	18.87	11.61	11.61		0.00	0.00	16.00	20.25	35.00	603,124,000	420,123	506,078	658,016	-3.02	-1.73	-4.09	-7.14	0.10	0.00	1.72	0.10	4.20	4.66	646,700,032	-106,691,000	-6.06	7.80	82,896,000	228,983,008	0.00	-127,575,000	49,315,130	47,999,895	9,523,284	10,066,202	19.57	0.26	3.76	185,407,008	-63,560,624	-99,761,000	-0.06	-196.19	62,997,000	-130.66	-128.71	-153.90	79.74	1.18	0.12	0.00	-26.67	-6,256.74	8.60	1.96	0.00	4.34	1.04
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FOLD	Amicus Therapeutics Inc.	194.31	1,195	19.77	13	2.1	-3.28	-9.52	4.22	0.00	6.25	25.39	22.66	16.47		0.00	0.00	12.50	24.65	31.00	5,326,411,000	1,803,890	2,568,529	2,520,315	-1.15	-0.78	-17.24	-27.04	0.54	0.00	1.34	1.45	4.96	5.24	5,427,289,600	-254,706,000	-21.31	22.10	245,608,000	440,579,008	137.57	-295,180,000	260,587,610	209,692,244	29,688,833	29,240,148	10.88	0.11	1.95	509,081,984	-123,438,000	-241,300,000	1.23	16.02	160,274,000	-109.06	-103.70	-120.18	88.37	3.76	0.50	0.00	-18.78	-67.97	38.30	0.95	0.00	0.56	1.08
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FPRX	Five Prime Therapeutics Inc.	400.60	287	15.17	7	1.6	-3.68	-1.30	214.73	209.43	1.75	24.70	17.67	8.12		0.00	0.00	14.00	27.29	34.00	691,427,600	708,009	1,565,682	1,113,202	-2.68	-2.08	-5.65	-7.29	0.25	0.00	1.22	1.06	5.18	5.35	518,757,856	-83,551,000	-6.21	30.34	17,096,000	46,301,000	48.62	-94,833,000	46,317,666	36,103,791	2,017,263	899,414	2.33	0.05	3.00	111,369,000	-44,870,876	-81,007,000	2.67	5.67	-92,976,000	-513.07	0.00	0.00	0.00	4.41	0.74	0.00	-26.17	-69.31	-31.40	0.48	0.00	3.19	47.10
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FREQ	Frequency Therapeutics Inc.	367.39	360	37.16	4	2.0	-1.77	-3.20	68.91	65.41	14.50	42.89	32.40	23.38		0.00	0.00	27.00	47.00	79.00	1,276,183,000	82,862	261,767	213,485	-10.29	-0.43	-3.61	-86.42	0.04	0.00	0.97	1.03	6.81	6.91	1,054,193,408	-22,776,000	-46.29	33.21	31,743,000	2,241,000	1.12	-21,812,000	33,734,692	25,739,570	4,638,572	4,044,829	15.37	0.15	6.65	224,231,008	-49,597,624	-60,098,000	-25.04	-1.48	12,947,000	-74.85	-71.75	-68.59	100.00	2.04	0.28	0.00	-7.33	-14.93	-53.60	1.03	0.00	12.49	57.92
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	FWP	Forward Pharma A/S	38.84	3,768	6.73	0	0.0	2.75	1.36	5.98	0.00	4.61	12.72	7.03	6.57		0.00	0.00	0.00	0.00	0.00	44,480,980	122,174	27,245	91,136	-0.49	-0.09	-13.79	-72.67	0.17	0.00	0.43	0.34	118.37	118.57	-22,862,216	-4,078,500	5.61	0.00	0	0	0.00	-3,630,000	95,073,864	1,330,874	5,580	14,212	0.35	0.00	9.37	75,626,000	0	0	9.36	0.72	0	0.00	0.00	0.00	0.00	2.74	0.02	0.00	-3.25	-4.67	0.00	0.00	0.00	0.00	13.57
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GALT	Galectin Therapeutics Inc.	79.94	2,969	2.10	1	2.0	-2.33	-3.67	-19.23	-21.38	1.50	3.85	2.46	2.64		0.00	0.00	3.82	3.82	3.82	122,715,700	343,592	249,799	260,375	-0.39	-0.68	-5.37	-3.16	-0.07	0.00	1.24	0.10	13.09	13.62	93,613,208	0	0.00	0.00	0	62,000	0.20	-20,887,000	57,077,055	41,195,935	4,770,427	5,044,291	18.15	0.20	0.57	32,556,000	-11,297,375	-18,946,000	0.51	4.09	0	0.00	0.00	0.00	0.00	2.23	0.10	0.00	-30.66	-51.22	0.00	0.00	0.00	29.01	17.35
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GBT	Global Blood Therapeutics Inc.	170.16	1,470	47.49	19	1.9	-1.76	-6.61	-12.04	-32.07	36.49	83.69	44.84	59.55		0.00	0.00	45.00	48.38	86.47	2,987,240,000	1,051,297	1,221,335	1,050,436	-4.62	-3.13	-10.28	-15.22	0.32	0.00	1.20	-0.10	7.01	7.63	2,571,639,552	-287,679,008	-8.94	30.39	84,616,000	158,964,000	34.73	-281,721,984	61,796,443	54,558,226	11,652,856	11,626,172	8.91	0.22	8.61	531,924,992	-139,215,872	-229,132,992	7.41	6.41	2,060,000	-344.28	0.00	0.00	98.73	1.63	0.13	0.00	-25.67	-50.50	0.00	1.39	0.00	1.77	1.08
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GERN	Geron Corporation	163.03	1,553	1.72	6	1.7	-2.27	-2.83	-3.91	28.15	0.75	2.40	1.74	1.74		0.00	0.00	2.23	3.00	4.00	546,431,200	3,406,145	2,536,254	2,990,840	-0.34	-0.30	-5.13	-5.87	0.49	0.00	0.71	0.68	9.47	9.60	339,172,960	-83,517,000	-4.06	906.88	374,000	29,679,000	12.75	-80,900,000	310,472,232	260,588,658	55,230,271	48,218,984	20.05	0.18	0.73	227,623,008	-33,988,124	-64,404,000	0.75	2.29	-38,803,000	-22,367.65	0.00	0.00	0.00	2.38	0.12	0.00	-23.24	-42.00	-17.60	0.00	0.00	0.16	56.20
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GILD	Gilead Sciences Inc.	256.51	759	66.70	27	2.4	-2.14	-0.55	13.38	4.87	56.56	85.97	61.03	68.11	2020-12-14	2.72	4.06	58.00	72.85	100.00	85,440,480,000	7,125,214	9,298,170	11,451,024	0.96	6.79	69.31	9.86	0.12	0.00	0.49	0.31	3.04	3.25	88,266,170,368	6,345,999,872	13.91	3.81	23,146,999,808	29,290,000,384	167.65	1,268,000,000	1,253,528,149	1,251,948,704	21,572,372	20,728,411	2.27	0.02	19.91	24,960,999,424	4,142,374,912	8,832,000,000	13.92	4.79	17,774,000,000	21.36	27.42	5.48	79.02	2.16	0.03	0.00	5.15	6.46	17.40	18.38	0.00	0.11	80.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GLMD	Galmed Pharmaceuticals Ltd.	144.80	1,802	3.75	5	1.8	-1.83	0.00	17.56	-33.16	2.96	6.44	3.58	4.20		0.00	0.00	2.90	5.67	10.00	81,412,000	216,967	132,707	93,463	-1.27	-1.29	-2.96	-2.91	-1.56	0.00	0.70	-0.13	9.79	9.81	21,582,162	-28,460,000	-0.76	0.00	0	247,000	0.46	-26,780,000	21,312,043	12,295,770	32,739	36,483	0.20	0.00	2.75	58,585,000	-12,997,000	-22,515,000	2.52	1.49	0	0.00	0.00	0.00	0.00	1.57	0.14	0.00	-25.21	-40.86	0.00	0.00	0.00	17.32	32.54
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GLPG	Galapagos NV	57.07	3,428	111.28	7	2.9	-0.04	3.30	-7.66	-51.33	93.01	274.03	111.43	159.21		0.00	0.00	90.30	110.64	140.46	0	223,616	260,268	166,188	-1.69	-6.96	-66.00	-15.99	-0.21	0.00	0.85	-0.89	9.05	9.08	7,271,129,088	0	0.00	0.00	0	0	1.07	0	65,411,767	41,957,968	665,915	1,077,651	1.94	0.00	0.00	0	0	0	25.49	4.37	468,570,000	0.00	-34.37	-70.90	-2.97	0.20	0.20	0.00	-2.01	-13.84	-77.60	0.00	0.00	0.00	11.77
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GLYC	GlycoMimetics Inc.	232.13	910	4.03	4	2.0	-1.71	6.33	49.81	-9.11	1.82	5.19	3.77	3.46		0.00	0.00	3.00	4.77	10.50	196,098,200	1,102,215	698,568	576,265	-1.13	-1.29	-3.58	-3.18	-0.25	0.00	0.99	0.29	14.55	14.83	46,212,936	-51,005,912	-0.91	4.62	10,000,000	3,029,131	2.19	-50,190,484	47,828,831	22,161,967	1,983,243	1,857,397	2.64	0.08	2.99	142,870,352	-23,770,730	-42,348,712	2.89	1.39	0	-512.76	0.00	0.00	100.00	1.68	0.03	0.00	-19.37	-32.87	0.00	0.22	0.00	2.15	78.59
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GMDA	Gamida Cell Ltd.	403.50	277	8.28	6	1.9	0.24	-15.85	53.90	86.81	2.60	11.20	8.33	5.58		0.00	0.00	12.00	15.17	17.00	487,276,200	1,308,459	841,271	432,225	-1.81	-1.25	-4.59	-6.80	0.15	0.00	0.41	1.05	5.26	5.39	355,725,632	-55,829,000	-6.37	0.00	0	7,805,000	12.89	-55,119,000	58,992,279	36,087,162	571,513	474,092	0.48	0.02	1.48	73,311,000	-44,519,000	-46,381,000	1.22	6.78	0	0.00	0.00	0.00	0.00	0.32	0.32	0.00	-38.27	-100.68	0.00	0.00	0.00	31.84	33.63
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GNCA	Genocea Biosciences Inc.	137.82	1,900	2.93	5	1.4	0.34	5.02	25.75	39.15	1.10	5.75	2.39	2.45		0.00	0.00	4.00	6.60	2.86	150,774,900	324,712	467,820	646,677	-1.40	-0.85	-2.09	-3.47	0.05	0.00	0.97	0.84	3.68	3.79	89,463,008	-44,398,000	-2.02	65.83	1,359,000	24,764,000	122.56	-38,085,000	51,635,257	27,477,186	1,631,969	1,709,911	4.08	0.04	1.70	87,625,000	-25,585,624	-40,995,000	0.39	7.47	0	-3,321.34	0.00	0.00	100.00	0.19	0.16	0.00	-34.09	-147.68	0.00	0.04	0.00	6.98	54.72
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GNPX	Genprex Inc.	220.55	997	4.57	3	2.0	7.78	16.88	40.18	221.31	1.17	7.03	3.69	3.38		0.00	0.00	5.00	6.67	8.00	182,547,500	5,138,957	1,437,869	1,693,300	-0.51	-3.68	-9.03	-1.07	-0.01	0.00	1.79	1.45	56.06	60.46	134,247,008	-15,138,750	-8.87	0.00	0	0	0.00	-15,139,425	43,053,668	30,183,920	3,181,840	3,365,863	1.74	0.08	0.53	21,058,386	-6,072,350	-11,764,402	0.58	7.85	0	0.00	0.00	0.00	0.00	6.70	1.11	0.00	-69.11	-114.23	0.00	0.00	0.00	17.55	23.37
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GOSS	Gossamer Bio Inc.	180.64	1,348	10.19	7	1.9	-4.05	-3.32	18.63	-24.69	7.52	16.79	9.87	11.82		0.00	0.00	12.00	20.86	29.00	806,354,100	696,518	691,942	692,610	-3.56	-2.89	-2.86	-3.67	0.15	0.00	0.97	-0.08	17.05	17.37	374,451,360	-208,647,008	-1.80	0.00	0	183,018,000	49.19	-233,454,000	75,927,877	47,665,984	7,888,104	8,372,482	8.32	0.13	7.78	555,377,984	-120,225,376	-183,764,000	5.21	1.95	0	0.00	0.00	0.00	0.00	3.94	0.12	0.00	-24.91	-60.56	0.00	0.00	0.00	11.05	85.07
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GRFS	Grifols S.A.	178.58	1,377	18.45	2	1.5	-2.79	-6.72	6.65	-19.29	13.40	25.73	18.94	18.68	2020-10-30	0.42	2.23	23.68	32.45	41.22	0	597,305	712,426	1,116,570	0.60	1.48	30.78	12.47	0.32	0.00	0.68	-0.29	1.30	2.93	26,121,715,712	0	0.00	0.00	0	0	99.16	0	261,425,110	1,106,580,857	2,458,766	2,849,497	3.82	0.00	0.00	0	0	0	3.56	5.19	2,341,232,000	0.00	23.07	12.75	42.16	2.71	0.09	94.30	4.27	12.09	3.00	0.00	0.00	0.00	45.62
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GRTS	Gritstone Oncology Inc.	7.99	4,071	20.56	4	2.6	-13.83	-7.68	642.24	194.35	2.54	35.20	6.17	5.05		0.00	0.00	4.00	17.75	35.00	997,520,100	3,252,585	3,400,175	1,197,251	-2.87	-2.28	-7.17	-10.46	0.35	0.00	1.26	0.98	3.21	3.35	979,099,328	-100,790,000	-9.71	274.10	3,572,000	25,860,000	35.93	-105,851,000	47,350,563	14,155,490	1,668,738	2,136,233	3.71	0.05	1.87	70,545,000	-64,781,000	-86,337,000	1.91	10.79	-78,531,000	-3,000.64	0.00	0.00	0.00	14.32	0.54	0.00	-40.46	-92.70	-4.60	0.10	0.00	9.02	65.43
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	GTHX	G1 Therapeutics Inc.	145.37	1,795	20.96	7	1.7	-1.92	-3.37	80.85	-6.26	8.80	25.79	18.02	16.47		0.00	0.00	21.00	26.10	50.00	813,041,600	808,747	1,393,848	836,428	-2.90	-3.91	-7.24	-5.47	-0.21	0.00	1.34	0.36	7.23	7.45	582,151,936	-108,337,000	-5.37	20.26	28,739,000	28,758,000	14.56	-109,348,000	38,045,935	29,113,510	6,656,158	7,583,563	4.11	0.29	6.27	238,342,000	-43,346,248	-82,245,000	5.19	4.04	0	-379.07	0.00	0.00	100.00	1.90	0.03	0.00	-23.67	-45.22	0.00	0.76	0.00	10.40	90.90
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HALO	Halozyme Therapeutics Inc.	411.26	258	48.65	12	2.4	-0.31	0.79	53.86	151.29	12.71	49.70	42.51	30.59		0.00	0.00	17.00	44.75	65.00	6,596,932,000	965,521	1,675,574	1,455,049	0.15	1.70	317.19	28.62	0.32	0.00	0.70	2.15	15.17	18.49	6,639,077,376	64,696,000	102.62	33.27	199,556,000	399,153,984	403.24	21,524,000	135,183,040	133,498,024	14,850,014	16,626,444	12.28	0.12	2.57	346,705,984	-12,367,375	-22,091,000	0.73	66.46	26,843,000	31.56	32.42	10.79	55.63	0.92	0.61	0.00	8.80	12.50	41.30	1.45	0.00	1.26	1.03
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HARP	Harpoon Therapeutics Inc.	309.46	525	20.72	9	1.4	-0.96	-14.24	30.31	0.00	10.27	25.24	17.01	15.78		0.00	0.00	25.00	31.89	38.00	670,094,900	116,187	254,327	237,308	-2.16	-2.13	-9.61	-10.19	8.29	0.00	0.98	0.82	3.42	3.49	409,999,424	-52,593,000	-7.80	33.65	12,186,000	14,053,000	23.14	-52,819,000	32,145,046	12,732,556	847,534	793,718	3.60	0.08	6.10	154,807,008	-1,526,750	40,269,000	2.40	8.62	-35,815,000	-448.37	0.00	0.00	0.00	1.12	0.17	0.00	-20.97	-62.89	174.70	0.50	0.00	11.09	79.95
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HGEN	Humanigen Inc.	158.73	1,609	18.78	6	1.7	-2.14	-9.01	68.13	859.50	1.55	33.95	13.96	13.70		0.00	0.00	25.00	29.33	35.00	990,520,800	608,707	884,960	557,899	-2.00	4.05	-9.41	4.64	0.03	0.00	0.26	1.73	6.15	6.19	919,736,384	0	0.00	0.00	0	0	0.00	-59,266,000	51,616,508	30,285,470	2,073,120	1,194,789	1.81	0.12	1.77	91,431,000	-27,799,624	-46,707,000	1.50	12.55	-2,150,000	0.00	0.00	0.00	0.00	4.65	2.52	0.00	-77.62	-183.48	0.00	0.00	0.00	40.28	30.56
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HOOK	HOOKIPA Pharma Inc.	669.71	68	11.99	7	1.6	-5.37	-0.25	8.70	-1.69	5.80	14.14	11.53	10.44		0.00	0.00	16.00	22.29	28.00	416,604,800	83,025	125,746	81,115	-1.63	-2.31	-7.34	-5.53	-0.18	0.00	1.46	0.36	5.24	5.65	256,824,496	-49,040,000	-5.24	14.24	18,039,000	10,585,000	11.48	-41,852,000	25,760,808	15,773,007	1,184,505	892,636	6.60	0.06	3.19	81,830,000	-30,420,250	-36,831,000	3.59	3.34	-34,370,000	-284.47	-271.86	-232.01	-178.72	5.34	0.05	0.00	-23.47	-38.41	98.20	0.70	0.00	11.32	47.29
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HRTX	Heron Therapeutics Inc.	216.30	1,033	17.57	10	1.6	-3.88	-2.12	8.06	-22.53	9.60	24.13	18.66	16.78		0.00	0.00	22.00	22.28	32.50	1,660,834,000	1,073,184	1,084,709	1,064,762	-2.47	-1.87	-7.12	-9.47	0.29	0.00	1.00	-0.02	2.99	3.60	1,375,747,584	-223,530,000	-6.16	13.34	103,116,000	24,847,000	8.97	-222,916,992	90,855,254	79,546,501	17,526,819	18,562,666	14.64	0.23	2.84	258,146,000	-88,009,128	-159,243,008	3.05	5.76	-83,033,000	-219.39	-216.78	-216.18	-114.35	3.82	0.11	0.00	-36.12	-79.25	-53.20	1.14	0.00	0.29	1.01
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	HTBX	Heat Biologics Inc.	249.08	819	8.76	4	2.0	9.09	26.96	6.05	0.00	1.40	30.10	6.62	7.87		0.00	0.00	9.95	11.14	20.00	183,366,000	5,485,292	1,688,321	8,047,759	-1.99	-1.07	-4.40	-6.44	0.10	0.00	0.52	1.56	30.91	31.33	41,322,696	-21,272,586	-1.94	9.51	4,343,893	1,940,134	1.61	-22,934,768	22,832,705	21,752,959	2,334,046	1,134,141	1.66	0.11	5.14	117,309,104	-9,578,329	-15,830,932	5.42	1.62	-9,964,500	-496.59	0.00	0.00	-177.03	7.43	1.69	0.00	-17.49	-33.73	13,096.60	0.38	0.00	3.01	12.27
HEALTH CARE	Biotechnology	Biotechnology	AMEX	IBIO	iBio Inc.	298.92	569	1.72	2	2.0	0.59	13.91	0.59	528.57	0.23	7.45	1.39	1.94		0.00	0.00	2.00	2.50	3.00	366,315,500	17,989,407	14,899,452	19,257,571	-0.42	-0.21	-4.08	-8.38	0.08	0.00	-0.53	1.53	16.62	16.84	269,779,232	-14,805,000	-18.22	139.06	1,940,000	32,834,000	41.02	-41,330,000	216,009,931	181,600,004	12,038,698	13,751,129	0.92	0.06	0.46	83,553,000	-12,476,500	-18,128,000	0.44	3.87	1,638,000	-880.00	0.00	0.00	100.00	2.03	2.03	0.00	-14.00	-49.97	279.60	0.02	0.00	0.91	8.10
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ICCC	ImmuCell Corporation	113.94	2,284	7.53	1	2.0	7.57	13.23	41.28	35.51	3.70	7.39	6.18	5.39		0.00	0.00	14.00	14.00	14.00	50,490,430	83,543	13,832	18,301	-0.21	-0.11	-35.69	-65.55	0.75	0.00	0.08	0.86	4.18	5.52	57,357,032	1,307,311	43.87	3.77	15,230,753	10,974,063	39.16	-1,521,398	7,212,920	5,157,237	4,073	3,398	0.54	0.00	0.82	5,910,695	-2,683,526	1,112,708	3.89	1.94	6,739,720	-6.49	8.58	-9.99	46.48	7.41	0.19	0.00	-1.57	-5.32	25.30	2.11	0.00	28.86	10.04
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ICPT	Intercept Pharmaceuticals Inc.	209.99	1,075	33.78	23	2.6	1.93	20.26	15.96	0.00	23.78	99.89	31.87	49.83		0.00	0.00	27.00	33.74	52.26	1,093,369,000	1,255,901	1,021,122	906,725	-9.75	-6.15	-3.46	-4.79	0.09	0.00	1.12	-0.71	3.26	3.44	1,046,025,152	-263,440,992	-3.97	3.48	300,921,984	564,648,000	0.00	-320,891,008	32,992,436	28,160,694	7,328,091	5,820,745	7.03	0.35	14.87	490,580,000	-94,288,752	-214,535,008	-3.95	-8.55	247,790,000	-88.58	-87.55	-106.64	97.66	2.18	0.26	0.00	-23.91	-143,254.91	28.40	9.14	0.00	15.70	88.73
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IDRA	Idera Pharmaceuticals Inc.	117.74	2,215	5.40	6	1.7	-9.70	0.00	80.00	236.16	0.81	6.14	4.34	2.66		0.00	0.00	5.00	7.83	10.00	210,799,700	683,145	468,732	331,948	-2.72	-0.74	-1.98	-8.04	0.03	0.00	0.95	1.65	4.26	4.59	181,758,192	-40,357,000	-4.50	0.00	0	995,000	0.00	-87,236,000	38,000,000	26,346,440	266,068	463,435	0.57	0.01	0.82	28,979,000	-21,525,876	-36,519,000	-0.92	-5.86	-24,091,000	0.00	0.00	0.00	0.00	10.51	0.85	0.00	-65.03	-2,280.60	0.00	0.00	0.00	27.74	25.17
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IDYA	IDEAYA Biosciences Inc.	274.92	665	17.61	9	1.4	-6.13	-9.41	33.11	109.09	2.95	20.75	14.60	11.94		0.00	0.00	20.00	25.00	30.00	545,347,900	112,241	240,396	219,562	-1.78	-1.27	-9.87	-14.49	0.34	0.00	0.88	1.15	5.14	5.19	238,029,344	-40,033,000	-5.95	26.55	8,967,000	7,086,000	3.63	-40,141,000	29,069,719	16,595,689	837,950	721,232	4.00	0.04	9.59	278,683,008	26,228,624	58,353,000	6.73	2.62	0	-461.50	0.00	0.00	79.16	6.53	0.42	0.00	-12.21	-26.25	0.00	0.40	0.00	13.64	59.18
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IGMS	IGM Biosciences Inc.	171.35	1,456	96.80	9	1.6	-1.22	-5.56	82.50	162.76	27.55	133.00	80.39	65.75		0.00	0.00	75.00	92.44	114.00	3,127,556,000	151,081	322,323	185,482	-26.20	-1.96	-3.69	-49.39	0.04	0.00	0.93	1.31	13.57	13.90	2,841,302,016	-73,584,000	-38.61	0.00	0	12,880,000	6.85	-71,548,000	25,490,610	7,762,644	2,557,193	2,314,599	5.06	0.31	5.87	180,236,000	-43,351,752	-56,606,000	8.35	11.59	-22,649,000	0.00	0.00	0.00	0.00	1.79	0.57	0.00	-19.33	-32.32	0.00	0.00	0.00	43.34	58.55
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IMGN	ImmunoGen Inc.	230.06	921	7.65	8	2.1	-1.04	-3.65	29.66	61.84	1.95	8.10	6.62	4.96		0.00	0.00	6.00	9.44	17.00	1,505,106,000	2,597,944	2,441,322	2,523,799	-0.43	-0.77	-17.96	-9.58	-0.22	0.00	1.30	1.01	2.12	2.20	1,220,404,736	-46,049,000	-26.50	13.36	91,365,000	24,667,000	0.00	-70,946,000	194,709,705	176,159,816	27,235,886	20,586,156	10.20	0.15	1.00	188,216,992	-30,088,750	-119,712,000	-0.25	-31.10	-32,251,000	-52.94	-50.40	-77.65	-10.62	1.30	0.27	0.00	-12.04	0.00	37.00	0.55	0.00	0.54	73.63
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IMMP	Immutep Limited	105.02	2,451	3.15	3	2.0	-1.56	-5.97	73.08	64.10	0.53	7.95	2.80	1.71		0.00	0.00	4.94	5.94	7.91	44,520	1,474,199	7,624,443	2,559,020	-0.43	-0.27	-7.37	-11.85	0.23	0.00	0.78	0.95	8.83	9.26	156,041,904	0	0.00	0.00	0	0	27.18	0	648,725,286	46,116,233	31,127	248,188	0.00	0.00	0.00	0	0	0	0.80	3.94	-6,656,699	0.00	-95.49	-98.03	-48.45	1.81	0.25	0.00	-21.62	-46.69	23.40	0.00	0.00	0.00	1.25
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IMUX	Immunic Inc.	130.49	2,002	17.28	6	1.5	-4.21	-7.30	13.16	108.07	4.19	23.39	17.82	15.37		0.00	0.00	19.36	22.92	45.00	373,758,900	126,175	244,075	409,057	-3.11	-2.70	-5.56	-6.40	0.42	0.00	0.94	1.25	16.72	17.13	241,575,856	-51,392,000	-4.70	0.00	0	1,000,000	0.61	-40,549,000	20,718,340	13,632,046	931,650	1,047,912	3.83	0.07	6.43	133,183,000	-30,019,876	-38,426,000	7.86	2.20	0	0.00	0.00	0.00	0.00	4.67	0.47	0.00	-26.89	-36.30	0.00	0.00	0.00	27.95	46.78
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INCY	Incyte Corporation	380.61	334	99.39	16	2.2	-1.10	5.78	17.00	28.68	62.48	110.37	87.03	93.47		0.00	0.00	89.00	105.69	133.00	22,009,110,000	931,311	1,096,744	1,315,760	-1.55	3.55	-64.04	27.57	0.19	0.00	0.66	0.84	3.45	3.56	19,773,589,504	-258,054,000	-76.63	8.05	2,456,581,888	70,863,000	2.96	-334,542,016	218,996,090	185,110,825	4,899,980	4,576,216	4.65	0.03	7.92	1,734,800,000	-89,489,624	-100,302,000	10.92	9.10	890,399,000	-12.65	-10.51	-13.62	7.17	1.23	0.13	0.00	-5.96	-13.90	12.50	11.31	0.00	1.34	94.48
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INFI	Infinity Pharmaceuticals Inc.	146.07	1,785	3.81	4	2.4	-3.54	9.48	252.78	176.22	0.60	4.38	2.38	1.37		0.00	0.00	2.00	4.13	7.00	253,616,700	2,003,237	1,592,880	802,555	-0.71	-0.53	-5.36	-7.19	0.21	0.00	0.75	1.58	4.20	4.42	223,395,648	-39,317,000	-5.68	140.41	1,591,000	2,075,000	0.00	-41,275,000	64,206,758	44,732,848	551,505	193,713	0.42	0.01	0.64	41,285,000	-24,043,250	-36,104,000	-0.22	-17.01	-31,375,000	-2,502.70	0.00	0.00	0.00	4.26	0.73	0.00	-46.92	-1,839.35	44.60	0.03	0.00	3.25	48.98
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INMB	INmune Bio Inc.	133.78	1,955	20.56	4	1.7	0.39	-23.43	154.14	329.88	2.20	29.99	13.66	9.46		0.00	0.00	15.00	20.00	26.00	275,414,000	562,259	278,021	473,184	-0.99	-1.39	-20.75	-14.91	-0.52	0.00	0.74	1.69	17.58	17.73	254,486,560	0	0.00	0.00	0	156,226	0.38	-11,213,092	13,447,900	6,688,202	564,266	537,918	2.61	0.06	1.81	24,311,152	-3,083,807	-6,984,303	3.06	6.71	0	0.00	0.00	0.00	0.00	1.29	1.29	0.00	-20.80	-34.02	0.00	0.00	0.00	45.07	12.61
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INO	Inovio Pharmaceuticals Inc.	243.39	849	10.58	7	2.9	8.85	4.75	3.52	69.17	3.14	33.79	10.48	13.80		0.00	0.00	8.00	12.29	20.00	1,983,782,000	17,794,201	11,868,244	24,162,185	-1.32	-0.59	-8.00	-15.25	0.14	0.00	-0.35	1.22	8.37	9.14	1,262,163,712	-119,411,312	-10.57	598.15	2,110,127	74,622,776	23.03	-179,734,816	186,851,493	166,361,311	56,138,707	55,370,514	4.77	0.34	1.99	337,236,192	-78,882,632	-140,499,904	1.93	5.47	-82,005,389	-5,841.53	0.00	0.00	0.00	8.46	0.42	0.00	-26.14	-100.68	-72.80	0.02	0.00	2.17	36.49
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	INSM	Insmed Inc.	205.63	1,112	42.25	10	1.8	-3.67	7.13	28.85	0.00	12.09	43.94	37.78	30.76		0.00	0.00	38.00	51.80	60.00	4,467,917,000	1,040,327	850,022	926,978	-2.60	-2.75	-16.27	-15.27	-2.76	0.00	1.31	1.31	7.20	7.95	4,089,341,696	-211,332,992	-19.35	24.24	168,706,000	399,651,008	111.93	-244,864,992	101,868,000	95,008,954	9,166,366	10,381,907	10.49	0.12	5.78	588,753,024	-121,169,128	-196,960,000	3.51	12.05	112,255,000	-129.09	-125.27	-145.14	75.07	4.12	0.47	0.00	-16.97	-74.08	12.20	1.79	0.00	1.03	1.08
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IONS	Ionis Pharmaceuticals Inc.	184.64	1,305	62.52	19	2.6	-1.98	2.44	33.02	4.50	39.32	63.79	54.69	54.32		0.00	0.00	19.00	65.37	120.00	8,917,920,000	856,951	1,135,957	935,456	0.49	-0.72	126.68	-85.76	-0.53	0.00	0.85	0.35	9.70	10.37	7,343,746,560	128,645,000	57.09	7.87	932,664,000	819,931,008	51.04	72,574,000	139,823,135	132,829,182	7,775,093	7,069,694	5.30	0.07	16.69	2,333,498,112	218,051,744	215,847,008	9.89	6.32	654,727,000	12.16	13.79	7.87	44.19	2.00	0.03	0.00	2.37	3.78	-4.70	6.67	0.00	4.97	86.69
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IOVA	Iovance Biotherapeutics Inc.	119.38	2,186	44.61	11	1.8	-4.09	-12.41	20.24	119.73	18.70	54.21	45.16	35.72		0.00	0.00	35.00	51.45	60.00	6,822,428,000	1,076,961	1,239,915	1,567,881	-1.91	-2.05	-23.32	-23.20	-3.26	0.00	1.12	1.28	11.09	11.24	6,271,745,536	-257,400,000	-24.37	0.00	0	10,907,000	1.53	-254,752,000	146,687,334	119,014,768	15,529,292	16,782,335	10.87	0.11	4.87	714,147,968	-124,335,624	-196,264,000	4.86	9.19	0	0.00	0.00	0.00	0.00	4.51	0.44	0.00	-27.43	-47.76	0.00	0.00	0.00	0.77	99.22
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	IRWD	Ironwood Pharmaceuticals Inc.	125.46	2,086	10.19	6	2.8	-2.40	-7.20	2.62	0.00	7.99	13.23	11.57	10.45		0.00	0.00	9.00	11.33	14.00	1,671,414,000	2,033,838	1,357,152	1,911,613	0.70	1.21	14.59	8.55	0.22	0.00	0.66	-0.11	12.79	13.17	1,796,267,136	147,359,008	12.19	4.50	399,144,000	448,417,984	7,595.16	110,830,000	160,097,114	141,721,167	18,339,405	20,447,648	13.96	0.18	1.92	307,555,008	77,172,128	144,903,008	0.04	275.41	293,024,000	35.91	36.92	27.77	72.04	2.33	0.07	61.50	21.68	0.00	-21.10	2.52	0.00	2.96	1.09
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	ISEE	IVERIC bio Inc.	306.02	537	5.50	3	1.7	-3.85	-4.01	-9.69	0.00	2.64	7.98	6.46	5.26		0.00	0.00	11.00	13.00	15.00	512,326,400	764,976	824,635	903,834	-1.23	-0.80	-4.46	-6.64	0.13	0.00	1.26	0.11	11.68	11.76	244,611,664	-80,936,000	-3.02	0.00	0	130,000	0.06	-76,593,000	89,567,544	58,801,093	6,814,646	3,656,491	6.67	0.09	2.58	231,122,000	-32,000,876	-56,937,000	2.40	2.30	-39,644,000	0.00	0.00	0.00	0.00	3.76	0.10	0.00	-30.40	-50.38	0.00	0.00	0.00	0.65	92.40
HEALTH CARE	Biotechnology	Biotechnology	AMEX	ISR	IsoRay Inc.	53.46	3,503	2.09	3	2.0	-5.00	-13.28	422.50	0.00	0.35	2.81	0.85	0.68		0.00	0.00	1.25	1.45	1.60	191,897,400	9,191,846	12,550,316	3,520,240	-0.05	-0.03	-42.65	-74.67	1.10	0.00	0.30	1.02	2.43	3.12	194,402,464	-3,152,000	-61.68	19.94	9,749,000	956,000	18.76	-3,354,000	87,226,074	86,062,478	822,729	714,027	0.45	0.01	0.02	1,940,000	-2,420,250	-3,326,000	0.07	28.24	5,124,000	-34.40	-32.33	-34.29	52.66	5.52	0.54	0.00	-23.10	-55.49	3.00	0.14	0.00	1.28	7.87
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	JNCE	Jounce Therapeutics Inc.	104.81	2,458	11.85	4	2.6	-9.82	23.05	68.80	94.45	2.85	13.19	7.54	6.73		0.00	0.00	5.50	9.88	15.00	523,847,700	527,700	507,362	641,160	-3.01	-1.53	-3.93	-7.75	0.08	0.00	1.38	1.07	6.40	6.60	437,242,624	-100,524,000	-4.35	0.00	0	17,642,000	16.79	-101,981,000	39,851,475	18,015,258	1,064,093	1,374,761	2.88	0.05	2.62	104,247,000	-46,912,752	-85,727,000	3.07	3.87	121,996,000	0.00	0.00	0.00	0.00	10.18	0.37	0.00	-36.32	-68.79	0.00	0.00	0.00	23.14	63.38
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KALV	KalVista Pharmaceuticals Inc.	358.44	381	16.35	7	1.6	-0.55	-3.71	-3.65	-2.60	5.61	20.21	17.89	13.90		0.00	0.00	21.00	29.86	39.00	294,969,200	106,027	110,440	107,941	-2.08	-3.32	-7.87	-4.86	-0.13	0.00	0.83	0.41	7.40	7.56	234,887,136	-48,381,000	-4.86	43.49	5,401,000	1,354,000	2.08	-37,116,000	17,942,166	10,854,472	382,360	339,735	3.41	0.03	3.11	55,874,000	-27,961,250	-37,267,000	3.63	4.51	-27,504,000	-905.50	0.00	0.00	0.00	0.54	0.01	0.00	-32.60	-45.61	0.00	0.30	0.00	9.06	96.23
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KDMN	Kadmon Holdings Inc.	706.58	57	5.27	6	1.7	2.13	6.04	48.87	11.06	2.30	5.50	4.27	4.24		0.00	0.00	7.96	8.00	12.83	885,006,800	4,804,431	2,776,430	2,464,848	-0.59	-0.40	-8.89	-12.05	0.27	0.00	0.99	0.63	5.68	5.77	739,121,216	-88,016,000	-8.40	61.21	12,075,000	23,831,000	16.86	-94,876,000	171,512,945	123,432,721	28,319,147	29,708,425	12.88	0.17	0.93	159,700,992	-42,372,752	-77,249,000	0.57	9.26	3,806,000	-739.60	0.00	0.00	83.72	2.05	0.09	0.00	-32.37	-83.78	209.50	0.08	0.00	0.14	96.54
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KIN	Kindred Biosciences Inc.	346.07	410	4.79	7	2.0	-1.44	5.51	27.73	-46.99	3.10	11.93	4.26	4.30		0.00	0.00	9.00	10.89	14.00	191,721,200	268,370	255,051	318,433	-0.68	-0.77	-7.04	-6.40	-0.53	0.00	1.21	-0.14	11.83	12.71	155,627,648	-56,566,000	-2.75	39.76	3,914,000	23,482,000	30.68	-26,632,000	39,492,134	30,434,759	760,024	691,979	3.17	0.03	1.58	62,337,000	-33,035,000	-16,992,000	1.94	2.46	3,669,000	-1,521.67	0.00	0.00	-13.24	1.25	0.20	0.00	-32.39	-31.01	-5.50	0.10	0.00	6.16	67.90
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KMDA	Kamada Ltd.	123.22	2,122	6.73	2	2.0	-1.18	-5.87	-7.68	2.28	4.40	13.33	6.67	7.88		0.00	0.00	11.00	11.00	11.00	0	74,214	166,160	260,401	0.48	0.11	14.02	61.18	0.81	0.00	0.40	0.37	5.69	7.53	215,588,992	25,889,000	8.33	1.61	133,775,000	4,997,000	2.83	20,873,000	44,730,854	28,785,830	765,045	551,400	4.25	0.03	2.19	99,717,000	3,123,625	15,017,000	3.88	1.74	49,737,000	16.50	19.35	15.60	36.98	1.19	0.02	7.10	7.60	13.60	6.80	3.08	0.00	16.92	41.94
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KNSA	Kiniksa Pharmaceuticals Ltd.	186.58	1,282	19.72	6	1.6	-0.25	-2.47	27.56	31.71	10.30	28.67	18.02	19.11		0.00	0.00	25.00	34.00	40.00	1,345,843,000	422,836	359,518	361,914	-2.38	-2.80	-8.28	-7.04	-0.47	0.00	0.91	0.79	14.64	15.20	880,882,880	-134,642,000	-6.54	0.00	0	1,547,000	0.43	-139,520,992	31,637,433	26,797,738	4,028,902	2,240,324	10.62	0.14	5.35	364,395,008	-72,863,752	-119,511,000	5.28	3.74	0	0.00	0.00	0.00	0.00	0.40	0.14	0.00	-25.71	-45.71	0.00	0.00	0.00	6.18	87.31
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KOD	Kodiak Sciences Inc	67.92	3,216	145.91	11	2.4	-6.40	-11.29	55.21	157.21	35.49	169.98	139.81	80.12		0.00	0.00	52.00	124.91	170.00	7,787,290,000	284,930	399,118	324,028	-2.34	-4.27	-62.30	-38.48	-0.76	0.00	1.09	1.47	16.91	16.96	6,719,322,624	-104,899,000	-64.06	0.00	0	77,324,000	27.44	-102,129,000	50,775,669	25,833,563	2,938,944	3,539,816	8.94	0.10	8.56	380,449,984	-28,585,000	-67,702,000	6.35	22.99	0	0.00	0.00	0.00	0.00	6.91	0.53	0.00	-23.96	-59.82	0.00	0.00	0.00	14.43	77.91
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KPTI	Karyopharm Therapeutics Inc.	235.36	892	15.74	9	1.7	0.19	4.38	10.53	-4.94	13.39	29.61	15.81	16.99		0.00	0.00	15.60	22.00	32.00	1,156,268,000	2,561,896	2,383,383	1,750,188	-2.90	-1.88	-5.44	-8.36	0.16	0.00	1.34	0.41	5.21	5.42	977,037,696	-177,091,008	-5.52	10.73	91,081,000	129,446,000	154.53	-201,499,008	73,600,777	55,410,345	15,427,495	15,001,548	5.36	0.22	3.57	263,044,000	-93,401,624	-169,088,992	1.14	13.82	-83,854,000	-195.49	-194.43	-221.23	-62.77	0.19	0.00	0.00	-35.03	-280.56	62.20	1.31	0.00	9.60	93.49
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KRTX	Karuna Therapeutics Inc.	79.47	2,981	99.42	11	1.5	-3.29	1.11	7.48	3.24	52.62	123.73	100.70	90.16		0.00	0.00	115.00	130.82	163.00	2,755,715,000	207,828	138,606	187,230	-1.90	-2.80	-52.30	-36.81	-1.11	0.00	1.02	0.32	67.38	70.57	2,347,490,816	-56,157,000	-41.80	0.00	0	2,885,000	0.81	-52,319,000	26,806,566	18,127,672	1,426,245	1,618,179	10.38	0.12	12.87	344,896,992	-36,686,876	-53,731,000	6.94	14.32	0	0.00	0.00	0.00	0.00	3.29	0.02	0.00	-13.31	-20.13	0.00	0.00	0.00	14.53	87.42
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KRYS	Krystal Biotech Inc.	105.24	2,444	71.17	9	1.8	-2.51	2.98	66.48	25.54	33.08	73.30	57.60	48.99		0.00	0.00	54.00	87.56	115.00	1,438,656,000	80,408	147,262	156,074	-1.49	-2.95	-47.70	-24.13	-0.49	0.00	1.27	0.66	39.78	39.96	1,155,388,288	-27,377,000	-42.20	0.00	0	3,097,000	1.03	-27,141,000	19,707,620	13,197,011	1,365,882	1,370,112	8.45	0.09	14.53	286,364,992	-19,956,124	-25,082,000	15.31	4.65	0	0.00	0.00	0.00	0.00	2.60	0.10	0.00	-6.83	-10.66	0.00	0.00	0.00	27.46	74.21
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KURA	Kura Oncology Inc.	145.19	1,796	32.80	9	1.8	-5.01	-8.30	-1.68	193.34	6.35	43.00	36.55	25.38		0.00	0.00	34.00	45.00	60.00	2,235,379,000	475,378	855,169	728,326	-1.64	-1.97	-20.05	-17.45	-0.98	0.00	0.93	1.63	14.99	15.15	1,632,832,128	-84,441,504	-19.34	0.00	0	15,426,000	5.03	-81,331,000	64,818,089	50,852,979	5,870,747	4,682,022	5.13	0.10	5.74	325,412,992	-39,602,248	-65,455,000	5.41	6.06	0	0.00	0.00	0.00	0.00	5.72	0.73	0.00	-17.78	-30.12	0.00	0.00	0.00	4.14	84.74
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	KZR	Kezar Life Sciences Inc.	150.08	1,724	5.50	3	1.6	-4.01	1.48	8.06	0.00	2.18	9.79	5.64	5.20		0.00	0.00	5.73	12.00	14.67	265,117,200	163,829	190,582	404,160	-1.11	-1.06	-4.94	-5.30	1.02	0.00	0.66	1.02	24.21	24.84	115,772,704	-40,363,000	-2.87	0.00	0	5,699,000	3.79	-40,380,000	46,268,275	31,604,933	1,887,060	1,711,195	9.28	0.05	3.24	149,954,000	-19,684,376	-34,852,000	3.25	1.69	0	0.00	0.00	0.00	0.00	4.34	0.35	0.00	-20.23	-34.10	0.00	0.00	0.00	31.66	54.59
HEALTH CARE	Biotechnology	Biotechnology	AMEX	LCTX	Lineage Cell Therapeutics Inc.	180.49	1,349	2.40	5	2.2	-7.34	-3.23	96.72	141.82	0.58	3.03	1.80	1.16		0.00	0.00	3.00	4.80	7.00	388,477,900	2,666,438	1,639,796	1,139,268	-0.37	-0.18	-6.43	-14.39	0.12	0.00	1.24	1.27	4.94	5.13	362,689,280	-23,600,000	-15.37	133.74	2,712,000	2,840,000	3.15	-27,163,000	149,991,454	107,680,365	5,565,257	7,158,998	4.36	0.05	0.25	38,046,000	14,562,500	-19,635,000	0.78	3.07	3,103,000	-960.07	0.00	0.00	85.47	7.80	0.50	0.00	-13.79	-26.53	0.70	0.02	0.00	5.05	35.77
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LGND	Ligand Pharmaceuticals Incorporated	273.40	672	156.86	6	2.2	0.55	20.02	81.74	75.62	57.24	167.32	101.25	103.31		0.00	0.00	146.00	185.83	229.00	2,508,847,000	1,143,978	363,777	332,950	-0.99	6.09	-159.25	25.76	0.22	0.00	1.07	1.25	19.57	20.28	2,175,258,624	41,642,000	52.24	15.17	143,432,000	459,921,984	65.91	-16,111,000	16,081,319	15,389,416	9,911,148	10,140,168	30.92	0.01	49.41	795,070,016	47,354,500	46,710,000	43.37	3.62	53,027,000	4.99	29.03	-11.23	46.49	0.32	0.32	0.00	0.32	-2.08	68.70	8.71	0.00	4.21	1.46
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LIFE	aTyr Pharma Inc.	121.42	2,152	3.94	3	1.7	-3.67	-3.67	22.74	-24.26	2.13	7.27	3.98	3.85		0.00	0.00	3.82	4.24	4.77	41,407,270	313,600	881,224	306,697	-2.32	-2.47	-1.70	-1.60	-0.26	0.00	0.77	-0.03	4.53	4.76	10,598,270	-16,335,000	-0.65	1.24	8,546,000	5,500,000	17.19	-17,265,000	10,185,458	8,265,863	67,757	41,038	0.05	0.01	3.57	36,146,000	-7,533,125	-14,816,000	3.22	1.22	-13,626,000	-198.14	-191.14	-202.02	-89.36	3.54	0.14	0.00	-24.79	-59.35	-19.60	1.15	0.00	5.25	64.57
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LJPC	La Jolla Pharmaceutical Company	124.26	2,104	6.46	3	2.3	14.13	19.63	77.47	0.00	3.36	9.38	4.67	4.81		0.00	0.00	4.75	6.37	10.92	154,977,600	1,168,798	1,057,193	676,345	-2.24	-0.63	-2.88	-8.75	0.04	0.00	0.92	0.32	1.69	2.25	253,671,392	-41,110,000	-6.17	8.54	29,718,000	126,655,000	0.00	-61,176,000	27,381,195	12,746,220	2,849,141	2,776,215	13.34	0.15	1.01	27,760,000	-28,324,250	-47,490,000	-3.27	-1.98	20,662,000	-145.93	-138.33	-205.86	87.84	14.18	0.10	0.00	-23.58	0.00	59.00	1.09	0.00	1.46	88.00
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LOGC	LogicBio Therapeutics Inc.	384.97	320	8.71	3	1.5	-4.08	2.47	55.26	0.00	3.05	11.60	7.63	7.16		0.00	0.00	20.00	21.33	24.00	288,621,300	104,183	134,965	118,916	-1.60	-1.39	-5.45	-6.12	0.42	0.00	1.63	0.56	5.98	6.21	254,196,128	-36,052,000	-7.05	87.29	2,912,000	16,296,000	73.11	-37,186,000	31,786,486	0	601,634	495,760	3.58	0.00	1.02	32,285,000	0	-33,138,000	0.94	9.26	0	-1,253.47	0.00	0.00	100.00	4.05	0.04	0.00	-41.90	-98.52	0.00	0.13	0.00	13.69	53.00
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LPTX	Leap Therapeutics Inc.	154.72	1,656	2.57	5	1.6	-1.15	6.20	33.85	46.07	1.15	3.18	1.97	2.03		0.00	0.00	2.50	2.55	5.10	155,110,100	766,953	965,161	724,978	-0.84	-0.42	-3.05	-6.12	0.06	0.00	0.88	0.84	8.67	8.70	97,783,128	-29,275,000	-3.34	86.92	1,125,000	648,000	1.22	-38,874,000	59,657,742	37,281,913	1,075,165	626,286	0.84	0.03	0.97	57,975,000	-16,063,875	-25,863,000	0.89	2.88	0	-2,605.42	0.00	0.00	100.00	1.31	0.17	0.00	-49.06	-98.13	0.00	0.02	0.00	12.04	59.02
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	LXRX	Lexicon Pharmaceuticals Inc.	110.81	2,349	8.24	3	2.3	-2.72	3.78	649.09	0.00	1.03	9.40	3.52	2.20		0.00	0.00	2.00	6.00	13.00	1,198,476,000	3,133,536	13,865,142	4,393,528	-0.98	-0.69	-8.44	-9.96	0.13	0.00	0.70	1.16	1.43	1.55	717,216,960	-211,452,000	-3.39	22.05	32,523,000	21,611,000	24.66	-104,217,000	141,496,541	0	11,992,934	9,492,401	0.82	0.00	0.95	111,446,000	0	-133,101,000	0.75	10.94	226,918,000	-655.77	0.00	0.00	0.00	3.32	0.61	-63.40	-42.76	-82.60	-97.70	0.31	0.00	0.90	91.96
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MACK	Merrimack Pharmaceuticals Inc.	27.08	3,932	7.45	1	3.5	-1.32	-2.61	94.01	0.00	1.49	8.86	6.38	4.32		0.00	0.00	4.00	4.00	4.00	101,020,800	53,017	1,848,914	487,486	0.10	-1.78	74.50	-4.22	-0.04	0.00	0.53	1.28	7.13	8.42	84,805,424	-4,666,000	-18.18	0.00	0	0	0.00	-2,594,000	13,380,243	0	560,853	655,121	0.14	0.00	1.18	15,814,000	0	-5,489,000	1.25	5.96	-9,100,000	0.00	0.00	0.00	0.00	1.80	0.48	0.00	-18.09	-14.08	0.00	0.00	0.00	3.24	60.31
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MBIO	Mustang Bio Inc.	275.62	659	4.49	4	1.7	-6.26	-4.67	62.09	30.96	1.78	5.22	3.71	3.32		0.00	0.00	7.00	10.75	13.00	314,192,600	3,051,579	3,737,367	1,793,210	-1.21	-0.86	-3.72	-5.57	0.13	0.00	1.40	0.62	9.87	9.91	262,112,992	-50,417,000	-5.20	0.00	0	2,293,000	3.00	-55,616,000	64,392,968	50,502,212	5,161,230	4,537,315	1.10	0.10	1.16	75,251,000	-30,352,124	-37,334,000	1.26	3.57	0	0.00	0.00	0.00	0.00	6.32	0.08	0.00	-38.25	-80.10	0.00	0.00	0.00	22.42	26.32
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MBRX	Moleculin Biotech Inc.	34.62	3,827	1.04	0	1.7	0.00	1.96	46.48	17.52	0.32	1.97	0.86	0.94		0.00	0.00	0.00	0.00	0.00	64,963,150	2,243,211	3,023,506	2,536,390	-0.34	-0.36	-3.04	-2.89	-0.58	0.00	0.94	0.67	3.72	4.44	53,721,436	-20,854,000	-2.58	0.00	0	304,000	2.10	-18,513,000	62,464,564	51,874,946	2,428,972	2,334,252	0.61	0.04	0.21	12,795,000	-18,641,500	-19,324,000	0.23	4.44	0	0.00	0.00	0.00	0.00	0.06	0.06	0.00	-45.75	-110.72	0.00	0.00	0.00	11.16	22.85
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MCRB	Seres Therapeutics Inc.	274.20	669	24.05	7	2.0	-3.18	-3.65	-20.76	628.79	2.52	38.50	26.98	18.00		0.00	0.00	24.00	37.50	49.00	2,266,606,000	592,868	1,124,337	1,462,078	-1.20	-0.64	-19.98	-37.58	0.43	0.00	0.99	1.18	6.58	6.73	2,010,513,280	-82,555,000	-24.35	86.39	23,273,000	41,821,000	22.24	-89,653,000	91,248,238	63,268,791	7,086,063	4,871,748	5.38	0.13	3.27	297,913,984	-44,074,876	-89,730,000	2.06	11.66	-45,636,000	-384.24	0.00	0.00	-272.69	5.74	2.57	0.00	-23.27	-115.06	-79.80	0.31	0.00	9.26	81.20
HEALTH CARE	Biotechnology	Biotechnology	NASDAQ	MDGL	Madrigal Pharmaceuticals Inc.	172.69	1,439	120.10	14	2.1	0.29	9.47	-6.17	46.91	56.82	137.28	116.35	111.65		0.00	0.00	123.00	170.00	230.00	1,852,108,000	224,308	160,408	155,744	-11.07	-15.74	-10.85	-7.63	-0.26	0.00	0.76	1.06	6.81	6.84	1,522,446,720	-176,688,992	-8.62	0.00	0	863,000	0.30	-170,860,992	15,466,451	6,677,950	2,743,496	2,497,066	16.48	0.35	21.72	335,936,992	-57,173,000	-114,896,000	18.73	6.41	0	0.00	0.00	0.00	0.00	0.21	0.21	0.00	-27.81	-46.81	0.00	0.00	0.00	19.47	93.86
HEALTH CARE